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Results: 1 to 20 of 109

1.

AlphaB-crystallin modulates protein aggregation of abnormal desmin.

Wang X, Klevitsky R, Huang W, Glasford J, Li F, Robbins J.

Circ Res. 2003 Nov 14;93(10):998-1005. Epub 2003 Oct 23.

PMID:
14576194
[PubMed - indexed for MEDLINE]
Free Article
2.

Expression of R120G-alphaB-crystallin causes aberrant desmin and alphaB-crystallin aggregation and cardiomyopathy in mice.

Wang X, Osinska H, Klevitsky R, Gerdes AM, Nieman M, Lorenz J, Hewett T, Robbins J.

Circ Res. 2001 Jul 6;89(1):84-91.

PMID:
11440982
[PubMed - indexed for MEDLINE]
Free Article
3.

Exercise reverses preamyloid oligomer and prolongs survival in alphaB-crystallin-based desmin-related cardiomyopathy.

Maloyan A, Gulick J, Glabe CG, Kayed R, Robbins J.

Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):5995-6000. Epub 2007 Mar 26.

PMID:
17389375
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The specificity of the interaction between αB-crystallin and desmin filaments and its impact on filament aggregation and cell viability.

Elliott JL, Der Perng M, Prescott AR, Jansen KA, Koenderink GH, Quinlan RA.

Philos Trans R Soc Lond B Biol Sci. 2013 Mar 25;368(1617):20120375. doi: 10.1098/rstb.2012.0375. Print 2013 May 5.

PMID:
23530264
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Manipulation of death pathways in desmin-related cardiomyopathy.

Maloyan A, Sayegh J, Osinska H, Chua BH, Robbins J.

Circ Res. 2010 May 14;106(9):1524-32. doi: 10.1161/CIRCRESAHA.109.212639. Epub 2010 Apr 1.

PMID:
20360253
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Doxycycline attenuates protein aggregation in cardiomyocytes and improves survival of a mouse model of cardiac proteinopathy.

Zheng H, Tang M, Zheng Q, Kumarapeli AR, Horak KM, Tian Z, Wang X.

J Am Coll Cardiol. 2010 Oct 19;56(17):1418-26. doi: 10.1016/j.jacc.2010.01.075.

PMID:
20947000
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Desmin filaments and cardiac disease: establishing causality.

Wang X, Osinska H, Gerdes AM, Robbins J.

J Card Fail. 2002 Dec;8(6 Suppl):S287-92. Review.

PMID:
12555134
[PubMed - indexed for MEDLINE]
8.

Biochemical and mechanical dysfunction in a mouse model of desmin-related myopathy.

Maloyan A, Osinska H, Lammerding J, Lee RT, Cingolani OH, Kass DA, Lorenz JN, Robbins J.

Circ Res. 2009 Apr 24;104(8):1021-8. doi: 10.1161/CIRCRESAHA.108.193516. Epub 2009 Mar 19.

PMID:
19299643
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Autophagy and p62 in cardiac proteinopathy.

Zheng Q, Su H, Ranek MJ, Wang X.

Circ Res. 2011 Jul 22;109(3):296-308. doi: 10.1161/CIRCRESAHA.111.244707. Epub 2011 Jun 9.

PMID:
21659648
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Genetic modification of the heart: chaperones and the cytoskeleton.

Kumarapeli AR, Wang X.

J Mol Cell Cardiol. 2004 Dec;37(6):1097-109. Review.

PMID:
15572040
[PubMed - indexed for MEDLINE]
11.

Desmin-related cardiomyopathy in transgenic mice: a cardiac amyloidosis.

Sanbe A, Osinska H, Saffitz JE, Glabe CG, Kayed R, Maloyan A, Robbins J.

Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):10132-6. Epub 2004 Jun 25.

PMID:
15220483
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Autophagy is an adaptive response in desmin-related cardiomyopathy.

Tannous P, Zhu H, Johnstone JL, Shelton JM, Rajasekaran NS, Benjamin IJ, Nguyen L, Gerard RD, Levine B, Rothermel BA, Hill JA.

Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9745-50. doi: 10.1073/pnas.0706802105. Epub 2008 Jul 9.

PMID:
18621691
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Reversal of amyloid-induced heart disease in desmin-related cardiomyopathy.

Sanbe A, Osinska H, Villa C, Gulick J, Klevitsky R, Glabe CG, Kayed R, Robbins J.

Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13592-7. Epub 2005 Sep 9.

PMID:
16155124
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Molecular mechanisms of α-crystallinopathy and its therapeutic strategy.

Sanbe A.

Biol Pharm Bull. 2011;34(11):1653-8. Review.

PMID:
22040875
[PubMed - indexed for MEDLINE]
Free Article
15.

Desmin aggregate formation by R120G alphaB-crystallin is caused by altered filament interactions and is dependent upon network status in cells.

Perng MD, Wen SF, van den IJssel P, Prescott AR, Quinlan RA.

Mol Biol Cell. 2004 May;15(5):2335-46. Epub 2004 Mar 5.

PMID:
15004226
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Mitochondrial dysfunction and apoptosis underlie the pathogenic process in alpha-B-crystallin desmin-related cardiomyopathy.

Maloyan A, Sanbe A, Osinska H, Westfall M, Robinson D, Imahashi K, Murphy E, Robbins J.

Circulation. 2005 Nov 29;112(22):3451-61.

PMID:
16316967
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Intermediate filament diseases: desminopathy.

Goldfarb LG, Olivé M, Vicart P, Goebel HH.

Adv Exp Med Biol. 2008;642:131-64.

PMID:
19181099
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Mouse model of desmin-related cardiomyopathy.

Wang X, Osinska H, Dorn GW 2nd, Nieman M, Lorenz JN, Gerdes AM, Witt S, Kimball T, Gulick J, Robbins J.

Circulation. 2001 May 15;103(19):2402-7.

PMID:
11352891
[PubMed - indexed for MEDLINE]
Free Article
19.

Atg7 induces basal autophagy and rescues autophagic deficiency in CryABR120G cardiomyocytes.

Pattison JS, Osinska H, Robbins J.

Circ Res. 2011 Jul 8;109(2):151-60. doi: 10.1161/CIRCRESAHA.110.237339. Epub 2011 May 26.

PMID:
21617129
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Aberrant protein aggregation is essential for a mutant desmin to impair the proteolytic function of the ubiquitin-proteasome system in cardiomyocytes.

Liu J, Tang M, Mestril R, Wang X.

J Mol Cell Cardiol. 2006 Apr;40(4):451-4. Epub 2006 Feb 14.

PMID:
16481005
[PubMed - indexed for MEDLINE]

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