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Results: 1 to 20 of 439

1.

CpG content affects gene silencing in mice: evidence from novel transgenes.

Chevalier-Mariette C, Henry I, Montfort L, Capgras S, Forlani S, Muschler J, Nicolas JF.

Genome Biol. 2003;4(9):R53. Epub 2003 Aug 14.

PMID:
12952532
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Silencing of episomal transgene expression in liver by plasmid bacterial backbone DNA is independent of CpG methylation.

Chen ZY, Riu E, He CY, Xu H, Kay MA.

Mol Ther. 2008 Mar;16(3):548-56. doi: 10.1038/sj.mt.6300399. Epub 2008 Feb 5.

PMID:
18253155
[PubMed - indexed for MEDLINE]
3.

Distal transgene insertion affects CpG island maintenance during differentiation.

Strathdee D, Whitelaw CB, Clark AJ.

J Biol Chem. 2008 Apr 25;283(17):11509-15. doi: 10.1074/jbc.M709805200. Epub 2008 Feb 28.

PMID:
18308728
[PubMed - indexed for MEDLINE]
Free Article
4.

lacZ sequences prevent regulated expression of housekeeping genes.

Cohen-Tannoudji M, Vandormael-Pournin S, Drezen J, Mercier P, Babinet C, Morello D.

Mech Dev. 2000 Jan;90(1):29-39.

PMID:
10585560
[PubMed - indexed for MEDLINE]
5.

An HF-1a/HF-1b/MEF-2 combinatorial element confers cardiac ventricular specificity and established an anterior-posterior gradient of expression.

Ross RS, Navankasattusas S, Harvey RP, Chien KR.

Development. 1996 Jun;122(6):1799-809.

PMID:
8674419
[PubMed - indexed for MEDLINE]
Free Article
6.

DNA methylation of Sleeping Beauty with transposition into the mouse genome.

Park CW, Kren BT, Largaespada DA, Steer CJ.

Genes Cells. 2005 Aug;10(8):763-76.

PMID:
16098140
[PubMed - indexed for MEDLINE]
7.

Transgene methylation in mice reflects copy number but not expression level.

Pena RN, Webster J, Kwan S, Korbel J, Whitelaw BA.

Mol Biotechnol. 2004 Mar;26(3):215-20.

PMID:
15004290
[PubMed - indexed for MEDLINE]
8.

Predicting aberrant CpG island methylation.

Feltus FA, Lee EK, Costello JF, Plass C, Vertino PM.

Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12253-8. Epub 2003 Sep 30.

PMID:
14519846
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The undermethylated state of a CpG island region in igf2 transgenes is dependent on the H19 enhancers.

Wise TL, Pravtcheva DD.

Genomics. 1999 Sep 15;60(3):258-71.

PMID:
10493826
[PubMed - indexed for MEDLINE]
10.

Methylation of CpG dinucleotides in the open reading frame of a testicular germ cell-specific intronless gene, Tact1/Actl7b, represses its expression in somatic cells.

Hisano M, Ohta H, Nishimune Y, Nozaki M.

Nucleic Acids Res. 2003 Aug 15;31(16):4797-804.

PMID:
12907721
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

A globin enhancer acts by increasing the proportion of erythrocytes expressing a linked transgene.

Sutherland HG, Martin DI, Whitelaw E.

Mol Cell Biol. 1997 Mar;17(3):1607-14.

PMID:
9032288
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

DNA methylation pattern of a tandemly repeated LacZ transgene indicates that most copies are silent.

Lau S, Jardine K, McBurney MW.

Dev Dyn. 1999 Jun;215(2):126-38.

PMID:
10373017
[PubMed - indexed for MEDLINE]
Free Article
13.

Inherent promoter bidirectionality facilitates maintenance of sequence integrity and transcription of parasitic DNA in mammalian genomes.

Kalitsis P, Saffery R.

BMC Genomics. 2009 Oct 27;10:498. doi: 10.1186/1471-2164-10-498.

PMID:
19860919
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Effect of the content of unmethylated CpG dinucleotides in plasmid DNA on the sustainability of transgene expression.

Mitsui M, Nishikawa M, Zang L, Ando M, Hattori K, Takahashi Y, Watanabe Y, Takakura Y.

J Gene Med. 2009 May;11(5):435-43. doi: 10.1002/jgm.1317.

PMID:
19291673
[PubMed - indexed for MEDLINE]
15.

cis-acting DNA regulatory elements, including the retinoic acid response element, are required for tissue specific laminin B1 promoter/lacZ expression in transgenic mice.

Sharif KA, Li C, Gudas LJ.

Mech Dev. 2001 May;103(1-2):13-25. Erratum in: Mech Dev 2001 Sep;107(1-2):207.

PMID:
11335108
[PubMed - indexed for MEDLINE]
16.

Silencing of caspase-8 in murine hepatocellular carcinomas is mediated via methylation of an essential promoter element.

Liedtke C, Zschemisch NH, Cohrs A, Roskams T, Borlak J, Manns MP, Trautwein C.

Gastroenterology. 2005 Nov;129(5):1602-15.

PMID:
16285959
[PubMed - indexed for MEDLINE]
17.

Paradoxical methylation of the tyrosine hydroxylase gene in mouse preimplantation embryos.

Arányi T, Kerjean A, Tóth S, Mallet J, Meloni R, Páldi A.

Genomics. 2002 Dec;80(6):558-63.

PMID:
12504847
[PubMed - indexed for MEDLINE]
18.

A gene-specific promoter in transgenic mice directs testis-specific demethylation prior to transcriptional activation In vivo.

Zhang LP, Stroud JC, Walter CA, Adrian GS, McCarrey JR.

Biol Reprod. 1998 Aug;59(2):284-92.

PMID:
9687297
[PubMed - indexed for MEDLINE]
Free Article
19.

DNA methylation represses transcription in vivo.

Siegfried Z, Eden S, Mendelsohn M, Feng X, Tsuberi BZ, Cedar H.

Nat Genet. 1999 Jun;22(2):203-6.

PMID:
10369268
[PubMed - indexed for MEDLINE]
20.

Retinoblastoma gene promoter directs transgene expression exclusively to the nervous system.

Jiang Z, Guo Z, Saad FA, Ellis J, Zacksenhaus E.

J Biol Chem. 2001 Jan 5;276(1):593-600.

PMID:
11016928
[PubMed - indexed for MEDLINE]
Free Article
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