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Items: 1 to 20 of 568

2.

Rat PXR reporter-gene activity correlates with the induction of CYP3A in rat precision-cut liver slices.

Cui X, Thomas A, Montgomery D, Gu C, Morrison RA, White RE, Cheng KC.

Comb Chem High Throughput Screen. 2005 Jun;8(4):341-6.

PMID:
16101010
3.

Di-n-butyl phthalate activates constitutive androstane receptor and pregnane X receptor and enhances the expression of steroid-metabolizing enzymes in the liver of rat fetuses.

Wyde ME, Kirwan SE, Zhang F, Laughter A, Hoffman HB, Bartolucci-Page E, Gaido KW, Yan B, You L.

Toxicol Sci. 2005 Aug;86(2):281-90. Epub 2005 May 18.

4.

Sterol regulatory element binding protein 1 interacts with pregnane X receptor and constitutive androstane receptor and represses their target genes.

Roth A, Looser R, Kaufmann M, Meyer UA.

Pharmacogenet Genomics. 2008 Apr;18(4):325-37. doi: 10.1097/FPC.0b013e3282f706e0.

PMID:
18334917
5.

DHA down-regulates phenobarbital-induced cytochrome P450 2B1 gene expression in rat primary hepatocytes by attenuating CAR translocation.

Li CC, Lii CK, Liu KL, Yang JJ, Chen HW.

Toxicol Appl Pharmacol. 2007 Dec 15;225(3):329-36. Epub 2007 Aug 23.

PMID:
17904175
7.

CAR and PXR expression and inducibility of CYP2B and CYP3A activities in rat and rabbit lungs.

Chirulli V, Longo V, Marini S, Mazzaccaro A, Fiorio R, Gervasi PG.

Life Sci. 2005 Apr 15;76(22):2535-46.

PMID:
15769478
8.
9.

Induction of hepatic aromatase by p,p'-DDE in adult male rats.

You L, Sar M, Bartolucci E, Ploch S, Whitt M.

Mol Cell Endocrinol. 2001 Jun 10;178(1-2):207-14.

PMID:
11403911
10.

Effects of intrauterine undernutrition on the expression of CYP3A23/3A1, PXR, CAR and HNF4alpha in neonate rats.

Ni S, Wang X, Wang J, Lu S, Zeng S, Zhao Z, Yu L, Chen S.

Biopharm Drug Dispos. 2008 Dec;29(9):501-10. doi: 10.1002/bdd.635.

PMID:
19058292
11.

Modulation of testosterone-metabolizing hepatic cytochrome P-450 enzymes in developing Sprague-Dawley rats following in utero exposure to p,p'-DDE.

You L, Chan SK, Bruce JM, Archibeque-Engle S, Casanova M, Corton JC, Heck H.

Toxicol Appl Pharmacol. 1999 Jul 15;158(2):197-205.

PMID:
10406934
12.

The induction of cytochrome P450 3A5 (CYP3A5) in the human liver and intestine is mediated by the xenobiotic sensors pregnane X receptor (PXR) and constitutively activated receptor (CAR).

Burk O, Koch I, Raucy J, Hustert E, Eichelbaum M, Brockmöller J, Zanger UM, Wojnowski L.

J Biol Chem. 2004 Sep 10;279(37):38379-85. Epub 2004 Jul 12.

13.

Comparative pharmacodynamics of CYP2B induction by DDT, DDE, and DDD in male rat liver and cultured rat hepatocytes.

Nims RW, Lubet RA, Fox SD, Jones CR, Thomas PE, Reddy AB, Kocarek TA.

J Toxicol Environ Health A. 1998 Mar 27;53(6):455-77.

PMID:
9537282
14.

The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity.

Zhang J, Huang W, Qatanani M, Evans RM, Moore DD.

J Biol Chem. 2004 Nov 19;279(47):49517-22. Epub 2004 Sep 8.

15.

CYP3A induction by liver x receptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor.

Shenoy SD, Spencer TA, Mercer-Haines NA, Alipour M, Gargano MD, Runge-Morris M, Kocarek TA.

Drug Metab Dispos. 2004 Jan;32(1):66-71.

16.

Endocrine disruptors induce cytochrome P450 by affecting transcriptional regulation via pregnane X receptor.

Mikamo E, Harada S, Nishikawa J, Nishihara T.

Toxicol Appl Pharmacol. 2003 Nov 15;193(1):66-72.

PMID:
14613717
17.

Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation.

Zhang H, LeCulyse E, Liu L, Hu M, Matoney L, Zhu W, Yan B.

Arch Biochem Biophys. 1999 Aug 1;368(1):14-22.

PMID:
10415106
18.

Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity.

Guo GL, Lambert G, Negishi M, Ward JM, Brewer HB Jr, Kliewer SA, Gonzalez FJ, Sinal CJ.

J Biol Chem. 2003 Nov 14;278(46):45062-71. Epub 2003 Aug 15.

19.

Role of the nuclear xenobiotic receptors CAR and PXR in induction of cytochromes P450 by non-dioxinlike polychlorinated biphenyls in cultured rat hepatocytes.

Gährs M, Roos R, Andersson PL, Schrenk D.

Toxicol Appl Pharmacol. 2013 Oct 1;272(1):77-85. doi: 10.1016/j.taap.2013.05.034. Epub 2013 Jun 12.

PMID:
23770461
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