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Items: 1 to 20 of 129

1.

A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system.

Miranda KM, Paolocci N, Katori T, Thomas DD, Ford E, Bartberger MD, Espey MG, Kass DA, Feelisch M, Fukuto JM, Wink DA.

Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9196-201. Epub 2003 Jul 15.

PMID:
12865500
2.

The nitroxyl anion (HNO) is a potent dilator of rat coronary vasculature.

Favaloro JL, Kemp-Harper BK.

Cardiovasc Res. 2007 Feb 1;73(3):587-96. Epub 2006 Nov 18.

PMID:
17189622
3.

Comparison of the NO and HNO donating properties of diazeniumdiolates: primary amine adducts release HNO in Vivo.

Miranda KM, Katori T, Torres de Holding CL, Thomas L, Ridnour LA, McLendon WJ, Cologna SM, Dutton AS, Champion HC, Mancardi D, Tocchetti CG, Saavedra JE, Keefer LK, Houk KN, Fukuto JM, Kass DA, Paolocci N, Wink DA.

J Med Chem. 2005 Dec 29;48(26):8220-8.

PMID:
16366603
4.

Effect of nitroxyl on the hamster retinal nitridergic pathway.

Sáenz DA, Bari SE, Salido E, Chianelli M, Rosenstein RE.

Neurochem Int. 2007 Nov-Dec;51(6-7):424-32. Epub 2007 May 3.

PMID:
17543420
5.

Redox variants of NO (NO{middle dot} and HNO) elicit vasorelaxation of resistance arteries via distinct mechanisms.

Favaloro JL, Kemp-Harper BK.

Am J Physiol Heart Circ Physiol. 2009 May;296(5):H1274-80. doi: 10.1152/ajpheart.00008.2009. Epub 2009 Feb 27.

PMID:
19252101
6.

Quantitative detection of nitroxyl upon trapping with glutathione and labeling with a specific fluorogenic reagent.

Johnson GM, Chozinski TJ, Salmon DJ, Moghaddam AD, Chen HC, Miranda KM.

Free Radic Biol Med. 2013 Oct;63:476-84. doi: 10.1016/j.freeradbiomed.2013.05.011. Epub 2013 May 16. Erratum in: Free Radic Biol Med. 2014 Dec;77:390.

PMID:
23685286
7.

Xanthine oxidase converts nitric oxide to nitroxyl that inactivates the enzyme.

Saleem M, Ohshima H.

Biochem Biophys Res Commun. 2004 Mar 5;315(2):455-62.

PMID:
14766230
8.

Chronic administration of the HNO donor Angeli's salt does not lead to tolerance, cross-tolerance, or endothelial dysfunction: comparison with GTN and DEA/NO.

Irvine JC, Kemp-Harper BK, Widdop RE.

Antioxid Redox Signal. 2011 May 1;14(9):1615-24. doi: 10.1089/ars.2010.3269. Epub 2011 Mar 3.

PMID:
20849324
9.

Ingress and reactive chemistry of nitroxyl-derived species within human cells.

Espey MG, Miranda KM, Thomas DD, Wink DA.

Free Radic Biol Med. 2002 Sep 15;33(6):827-34.

PMID:
12208370
10.

Mechanistic studies of oxidative decomposition of Angeli's salt and PAPA NONOate.

Bobko AA, Khramtsov VV.

Nitric Oxide. 2014 Aug 31;40:92-8. doi: 10.1016/j.niox.2014.05.013. Epub 2014 Jun 16.

PMID:
24947085
11.

Reactions of HNO with metal porphyrins: underscoring the biological relevance of HNO.

Doctorovich F, Bikiel DE, Pellegrino J, Suárez SA, Martí MA.

Acc Chem Res. 2014 Oct 21;47(10):2907-16. doi: 10.1021/ar500153c. Epub 2014 Sep 19. Review.

PMID:
25238532
12.

Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling.

Paolocci N, Saavedra WF, Miranda KM, Martignani C, Isoda T, Hare JM, Espey MG, Fukuto JM, Feelisch M, Wink DA, Kass DA.

Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10463-8. Epub 2001 Aug 21.

PMID:
11517312
13.

The effects of nitroxyl (HNO) on soluble guanylate cyclase activity: interactions at ferrous heme and cysteine thiols.

Miller TW, Cherney MM, Lee AJ, Francoleon NE, Farmer PJ, King SB, Hobbs AJ, Miranda KM, Burstyn JN, Fukuto JM.

J Biol Chem. 2009 Aug 14;284(33):21788-96. doi: 10.1074/jbc.M109.014282. Epub 2009 Jun 15.

PMID:
19531488
14.

Angeli's salt (Na2N2O3) is a precursor of HNO and NO: a voltammetric study of the reactive intermediates released by Angeli's salt decomposition.

Amatore C, Arbault S, Ducrocq C, Hu S, Tapsoba I.

ChemMedChem. 2007 Jun;2(6):898-903.

PMID:
17436261
15.

Nitroxyl triggers Ca2+ release from skeletal and cardiac sarcoplasmic reticulum by oxidizing ryanodine receptors.

Cheong E, Tumbev V, Abramson J, Salama G, Stoyanovsky DA.

Cell Calcium. 2005 Jan;37(1):87-96.

PMID:
15541467
16.

Comparison of the reactivity of nitric oxide and nitroxyl with heme proteins. A chemical discussion of the differential biological effects of these redox related products of NOS.

Miranda KM, Nims RW, Thomas DD, Espey MG, Citrin D, Bartberger MD, Paolocci N, Fukuto JM, Feelisch M, Wink DA.

J Inorg Biochem. 2003 Jan 1;93(1-2):52-60.

PMID:
12538052
17.

Nitroxyl (HNO) reacts with molecular oxygen and forms peroxynitrite at physiological pH. Biological Implications.

Smulik R, Dębski D, Zielonka J, Michałowski B, Adamus J, Marcinek A, Kalyanaraman B, Sikora A.

J Biol Chem. 2014 Dec 19;289(51):35570-81. doi: 10.1074/jbc.M114.597740. Epub 2014 Nov 5.

PMID:
25378389
18.

A comparison of the chemistry associated with the biological signaling and actions of nitroxyl (HNO) and nitric oxide (NO).

Fukuto JM, Cisneros CJ, Kinkade RL.

J Inorg Biochem. 2013 Jan;118:201-8. doi: 10.1016/j.jinorgbio.2012.08.027. Epub 2012 Oct 5. Review.

PMID:
23102503
19.

Nitroxyl and its anion in aqueous solutions: spin states, protic equilibria, and reactivities toward oxygen and nitric oxide.

Shafirovich V, Lymar SV.

Proc Natl Acad Sci U S A. 2002 May 28;99(11):7340-5.

PMID:
12032284
20.

On the distinction between nitroxyl and nitric oxide using nitronyl nitroxides.

Samuni U, Samuni Y, Goldstein S.

J Am Chem Soc. 2010 Jun 23;132(24):8428-32. doi: 10.1021/ja101945j.

PMID:
20504018
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