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Items: 1 to 20 of 92

1.

A prion protein epitope selective for the pathologically misfolded conformation.

Paramithiotis E, Pinard M, Lawton T, LaBoissiere S, Leathers VL, Zou WQ, Estey LA, Lamontagne J, Lehto MT, Kondejewski LH, Francoeur GP, Papadopoulos M, Haghighat A, Spatz SJ, Head M, Will R, Ironside J, O'Rourke K, Tonelli Q, Ledebur HC, Chakrabartty A, Cashman NR.

Nat Med. 2003 Jul;9(7):893-9.

PMID:
12778138
2.

Immunological mimicry of PrPC-PrPSc interactions: antibody-induced PrP misfolding.

Li L, Guest W, Huang A, Plotkin SS, Cashman NR.

Protein Eng Des Sel. 2009 Aug;22(8):523-9. doi: 10.1093/protein/gzp038. Epub 2009 Jul 14.

3.

Probing for prions: recognizing misfolded PrP.

Caughey B.

Nat Med. 2003 Jul;9(7):819-20. No abstract available.

PMID:
12835691
4.
5.

Antigenic features of prion proteins of sheep and of other mammalian species.

Groschup MH, Harmeyer S, Pfaff E.

J Immunol Methods. 1997 Aug 22;207(1):89-101.

PMID:
9328590
6.

Antigenic characterization of an abnormal isoform of prion protein using a new diverse panel of monoclonal antibodies.

Kim CL, Umetani A, Matsui T, Ishiguro N, Shinagawa M, Horiuchi M.

Virology. 2004 Mar 1;320(1):40-51.

7.

Antibodies to a nonconjugated prion protein peptide 95-123 interfere with PrP( Sc ) propagation in prion-infected cells.

Oboznaya MB, Gilch S, Titova MA, Koroev DO, Volkova TD, Volpina OM, Schätzl HM.

Cell Mol Neurobiol. 2007 May;27(3):271-84. Epub 2007 Jan 5.

PMID:
17205391
8.

Modification of blood cell PrP epitope exposure during prion disease.

Thackray AM, Ryder SJ, Bujdoso R.

Biochem J. 2005 Sep 1;390(Pt 2):563-71.

9.

Pathologic prion protein is specifically recognized in situ by a novel PrP conformational antibody.

Moroncini G, Mangieri M, Morbin M, Mazzoleni G, Ghetti B, Gabrielli A, Williamson RA, Giaccone G, Tagliavini F.

Neurobiol Dis. 2006 Sep;23(3):717-24. Epub 2006 Jul 28.

PMID:
16876426
10.

Detection of prion epitopes on PrP and PrP of transmissible spongiform encephalopathies using specific monoclonal antibodies to PrP.

Yuan FF, Biffin S, Brazier MW, Suarez M, Cappai R, Hill AF, Collins SJ, Sullivan JS, Middleton D, Multhaup G, Geczy AF, Masters CL.

Immunol Cell Biol. 2005 Dec;83(6):632-7.

PMID:
16266315
11.

Concealment of epitope by reduction and alkylation in prion protein.

Yuan J, Kinter M, McGeehan J, Perry G, Kneale G, Gambetti P, Zou WQ.

Biochem Biophys Res Commun. 2005 Jan 21;326(3):652-9.

PMID:
15596149
12.

[Unfolding chaperone as a prion protein relating molecule].

Hachiya NS, Sakasegawa Y, Kaneko K.

Rinsho Shinkeigaku. 2003 Nov;43(11):817-9. Review. Japanese.

PMID:
15152473
13.

Curative properties of antibodies against prion protein: a comparative in vitro study of monovalent fragments and divalent antibodies.

Alexandrenne C, Hanoux V, Dkhissi F, Boquet D, Couraud JY, Wijkhuisen A.

J Neuroimmunol. 2009 Apr 30;209(1-2):50-6. doi: 10.1016/j.jneuroim.2009.01.025. Epub 2009 Feb 20.

PMID:
19232746
14.

Molecular architecture of human prion protein amyloid: a parallel, in-register beta-structure.

Cobb NJ, Sönnichsen FD, McHaourab H, Surewicz WK.

Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):18946-51. Epub 2007 Nov 19.

15.

The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes.

Polymenidou M, Moos R, Scott M, Sigurdson C, Shi YZ, Yajima B, Hafner-Bratkovic I, Jerala R, Hornemann S, Wuthrich K, Bellon A, Vey M, Garen G, James MN, Kav N, Aguzzi A.

PLoS One. 2008;3(12):e3872. doi: 10.1371/journal.pone.0003872. Epub 2008 Dec 8.

16.

Chicken antibody against a restrictive epitope of prion protein distinguishes normal and abnormal prion proteins.

Miyamoto K, Kimura S, Nakamura N, Yokoyama T, Horiuchi H, Furusawa S, Matsuda H.

Biologicals. 2007 Oct;35(4):303-8. Epub 2007 Mar 23.

PMID:
17363268
17.

Conversion efficiency of bank vole prion protein in vitro is determined by residues 155 and 170, but does not correlate with the high susceptibility of bank voles to sheep scrapie in vivo.

Piening N, Nonno R, Di Bari M, Walter S, Windl O, Agrimi U, Kretzschmar HA, Bertsch U.

J Biol Chem. 2006 Apr 7;281(14):9373-84. Epub 2006 Feb 2.

18.

Generation of monoclonal antibody that distinguishes PrPSc from PrPC and neutralizes prion infectivity.

Horiuchi M, Karino A, Furuoka H, Ishiguro N, Kimura K, Shinagawa M.

Virology. 2009 Nov 25;394(2):200-7. doi: 10.1016/j.virol.2009.08.025. Epub 2009 Sep 18.

19.

Motif-grafted antibodies containing the replicative interface of cellular PrP are specific for PrPSc.

Moroncini G, Kanu N, Solforosi L, Abalos G, Telling GC, Head M, Ironside J, Brockes JP, Burton DR, Williamson RA.

Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10404-9. Epub 2004 Jul 6.

20.

The deletion of amino acids 114-121 in the TM1 domain of mouse prion protein stabilizes its conformation but does not affect the overall structure.

Thaa B, Zahn R, Matthey U, Kroneck PM, Bürkle A, Fritz G.

Biochim Biophys Acta. 2008 Jun;1783(6):1076-84. Epub 2007 Nov 29.

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