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Items: 1 to 20 of 227

1.

Granzyme B: a natural born killer.

Lord SJ, Rajotte RV, Korbutt GS, Bleackley RC.

Immunol Rev. 2003 Jun;193:31-8. Review.

PMID:
12752668
2.

Cytotoxic T lymphocyte-assisted suicide. Caspase 3 activation is primarily the result of the direct action of granzyme B.

Atkinson EA, Barry M, Darmon AJ, Shostak I, Turner PC, Moyer RW, Bleackley RC.

J Biol Chem. 1998 Aug 14;273(33):21261-6.

3.

Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.

Barry M, Heibein JA, Pinkoski MJ, Lee SF, Moyer RW, Green DR, Bleackley RC.

Mol Cell Biol. 2000 Jun;20(11):3781-94.

4.

Granzyme B-mediated death of pancreatic beta-cells requires the proapoptotic BH3-only molecule bid.

Estella E, McKenzie MD, Catterall T, Sutton VR, Bird PI, Trapani JA, Kay TW, Thomas HE.

Diabetes. 2006 Aug;55(8):2212-9.

5.

Cleavage of FLICE (caspase-8) by granzyme B during cytotoxic T lymphocyte-induced apoptosis.

Medema JP, Toes RE, Scaffidi C, Zheng TS, Flavell RA, Melief CJ, Peter ME, Offringa R, Krammer PH.

Eur J Immunol. 1997 Dec;27(12):3492-8.

PMID:
9464839
6.
7.

Cleavage of CPP32 by granzyme B represents a critical role for granzyme B in the induction of target cell DNA fragmentation.

Darmon AJ, Ley TJ, Nicholson DW, Bleackley RC.

J Biol Chem. 1996 Sep 6;271(36):21709-12.

9.
10.

Nuclear translocation of granzyme B in target cell apoptosis.

Pinkoski MJ, Heibein JA, Barry M, Bleackley RC.

Cell Death Differ. 2000 Jan;7(1):17-24.

12.

Possible key role of granzyme B in keratoacanthoma regression.

Batinac T, Zamolo G, Coklo M, Hadzisejdic I.

Med Hypotheses. 2006;66(6):1129-32. Epub 2006 Feb 23.

PMID:
16497444
13.

Cytotoxic T-cell-derived granzyme B activates the apoptotic protease ICE-LAP3.

Chinnaiyan AM, Hanna WL, Orth K, Duan H, Poirier GG, Froelich CJ, Dixit VM.

Curr Biol. 1996 Jul 1;6(7):897-9.

14.

Hepatic natural killer cells exclusively kill splenic/blood natural killer-resistant tumor cells by the perforin/granzyme pathway.

Vermijlen D, Luo D, Froelich CJ, Medema JP, Kummer JA, Willems E, Braet F, Wisse E.

J Leukoc Biol. 2002 Oct;72(4):668-76.

15.
16.

Granzyme B-mediated apoptosis proceeds predominantly through a Bcl-2-inhibitable mitochondrial pathway.

Pinkoski MJ, Waterhouse NJ, Heibein JA, Wolf BB, Kuwana T, Goldstein JC, Newmeyer DD, Bleackley RC, Green DR.

J Biol Chem. 2001 Apr 13;276(15):12060-7. Epub 2001 Jan 12.

17.

Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

Darmon AJ, Nicholson DW, Bleackley RC.

Nature. 1995 Oct 5;377(6548):446-8.

PMID:
7566124
19.

Perforin and granzyme B induce apoptosis in FasL-resistant colon carcinoma cells.

Vermijlen D, Froelich CJ, Luo D, Suarez-Huerta N, Robaye B, Wisse E.

Cancer Immunol Immunother. 2001 Jun;50(4):212-7.

PMID:
11459173
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