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Items: 1 to 20 of 222

1.

Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain.

McGill MA, McGlade CJ.

J Biol Chem. 2003 Jun 20;278(25):23196-203. Epub 2003 Apr 7.

2.

Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor.

Gupta-Rossi N, Le Bail O, Gonen H, Brou C, Logeat F, Six E, Ciechanover A, Israël A.

J Biol Chem. 2001 Sep 14;276(37):34371-8. Epub 2001 Jun 25.

3.

A novel PTB-PDZ domain interaction mediates isoform-specific ubiquitylation of mammalian Numb.

Nie J, Li SS, McGlade CJ.

J Biol Chem. 2004 May 14;279(20):20807-15. Epub 2004 Feb 27.

4.

c-Cbl binding and ubiquitin-dependent lysosomal degradation of membrane-associated Notch1.

Jehn BM, Dittert I, Beyer S, von der Mark K, Bielke W.

J Biol Chem. 2002 Mar 8;277(10):8033-40. Epub 2002 Jan 2.

5.

Numb regulates Notch1, but not Notch3, during myogenesis.

Beres BJ, George R, Lougher EJ, Barton M, Verrelli BC, McGlade CJ, Rawls JA, Wilson-Rawls J.

Mech Dev. 2011 May-Jun;128(5-6):247-57. doi: 10.1016/j.mod.2011.02.002. Epub 2011 Feb 26.

6.

Repression of activator protein-1-mediated transcriptional activation by the Notch-1 intracellular domain.

Chu J, Jeffries S, Norton JE, Capobianco AJ, Bresnick EH.

J Biol Chem. 2002 Mar 1;277(9):7587-97. Epub 2001 Dec 5.

7.

Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin.

Shenoy SK, McDonald PH, Kohout TA, Lefkowitz RJ.

Science. 2001 Nov 9;294(5545):1307-13. Epub 2001 Oct 4.

9.

LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation.

Nie J, McGill MA, Dermer M, Dho SE, Wolting CD, McGlade CJ.

EMBO J. 2002 Jan 15;21(1-2):93-102.

10.

Differential expression of mammalian Numb, Numblike and Notch1 suggests distinct roles during mouse cortical neurogenesis.

Zhong W, Jiang MM, Weinmaster G, Jan LY, Jan YN.

Development. 1997 May;124(10):1887-97.

11.

Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H).

Tamura K, Taniguchi Y, Minoguchi S, Sakai T, Tun T, Furukawa T, Honjo T.

Curr Biol. 1995 Dec 1;5(12):1416-23.

12.

Notch signaling induces rapid degradation of achaete-scute homolog 1.

Sriuranpong V, Borges MW, Strock CL, Nakakura EK, Watkins DN, Blaumueller CM, Nelkin BD, Ball DW.

Mol Cell Biol. 2002 May;22(9):3129-39.

13.

Numb regulates post-endocytic trafficking and degradation of Notch1.

McGill MA, Dho SE, Weinmaster G, McGlade CJ.

J Biol Chem. 2009 Sep 25;284(39):26427-38. doi: 10.1074/jbc.M109.014845. Epub 2009 Jun 30.

14.

Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase.

Qiu L, Joazeiro C, Fang N, Wang HY, Elly C, Altman Y, Fang D, Hunter T, Liu YC.

J Biol Chem. 2000 Nov 17;275(46):35734-7.

15.
16.

The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor.

Vecchione A, Marchese A, Henry P, Rotin D, Morrione A.

Mol Cell Biol. 2003 May;23(9):3363-72.

17.

SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation.

Wu G, Lyapina S, Das I, Li J, Gurney M, Pauley A, Chui I, Deshaies RJ, Kitajewski J.

Mol Cell Biol. 2001 Nov;21(21):7403-15.

18.

The intracellular region of Notch ligands Dll1 and Dll3 regulates their trafficking and signaling activity.

Heuss SF, Ndiaye-Lobry D, Six EM, Israël A, Logeat F.

Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11212-7. doi: 10.1073/pnas.0800695105. Epub 2008 Aug 1.

19.

Beta-catenin modulates the level and transcriptional activity of Notch1/NICD through its direct interaction.

Jin YH, Kim H, Ki H, Yang I, Yang N, Lee KY, Kim N, Park HS, Kim K.

Biochim Biophys Acta. 2009 Feb;1793(2):290-9. doi: 10.1016/j.bbamcr.2008.10.002. Epub 2008 Oct 22.

20.
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