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Results: 1 to 20 of 104

1.

The severe form of hypertension caused by the activating S810L mutation in the mineralocorticoid receptor is cortisone related.

Rafestin-Oblin ME, Souque A, Bocchi B, Pinon G, Fagart J, Vandewalle A.

Endocrinology. 2003 Feb;144(2):528-33.

PMID:
12538613
[PubMed - indexed for MEDLINE]
2.

Activating mineralocorticoid receptor mutation in hypertension exacerbated by pregnancy.

Geller DS, Farhi A, Pinkerton N, Fradley M, Moritz M, Spitzer A, Meinke G, Tsai FT, Sigler PB, Lifton RP.

Science. 2000 Jul 7;289(5476):119-23.

PMID:
10884226
[PubMed - indexed for MEDLINE]
Free Article
3.

Identification of steroid ligands able to inactivate the mineralocorticoid receptor harboring the S810L mutation responsible for a severe form of hypertension.

Pinon GM, Fagart J, Souque A, Auzou G, Vandewalle A, Rafestin-Oblin ME.

Mol Cell Endocrinol. 2004 Mar 31;217(1-2):181-8.

PMID:
15134816
[PubMed - indexed for MEDLINE]
4.

The role of 11β-hydroxysteroid dehydrogenase type 2 in human hypertension.

Ferrari P.

Biochim Biophys Acta. 2010 Dec;1802(12):1178-87. doi: 10.1016/j.bbadis.2009.10.017. Epub 2009 Nov 10. Review.

PMID:
19909806
[PubMed - indexed for MEDLINE]
Free Article
5.

Juvenile hypertension, the role of genetically altered steroid metabolism.

Ferrari P, Bianchetti M, Frey FJ.

Horm Res. 2001;55(5):213-23. Review.

PMID:
11740142
[PubMed - indexed for MEDLINE]
6.

The ligand-dependent interaction of mineralocorticoid receptor with coactivator and corepressor peptides suggests multiple activation mechanisms.

Hultman ML, Krasnoperova NV, Li S, Du S, Xia C, Dietz JD, Lala DS, Welsch DJ, Hu X.

Mol Endocrinol. 2005 Jun;19(6):1460-73. Epub 2005 Mar 10.

PMID:
15761029
[PubMed - indexed for MEDLINE]
7.

A mutation in the cofactor-binding domain of 11beta-hydroxysteroid dehydrogenase type 2 associated with mineralocorticoid hypertension.

Odermatt A, Dick B, Arnold P, Zaehner T, Plueschke V, Deregibus MN, Repetto H, Frey BM, Frey FJ, Ferrari P.

J Clin Endocrinol Metab. 2001 Mar;86(3):1247-52.

PMID:
11238516
[PubMed - indexed for MEDLINE]
8.

Crystal structure of a mutant mineralocorticoid receptor responsible for hypertension.

Fagart J, Huyet J, Pinon GM, Rochel M, Mayer C, Rafestin-Oblin ME.

Nat Struct Mol Biol. 2005 Jun;12(6):554-5. Epub 2005 May 22.

PMID:
15908963
[PubMed - indexed for MEDLINE]
9.

LLC-PK1 cells model 11 beta-hydroxysteroid dehydrogenase type 2 regulation of glucocorticoid access to renal mineralocorticoid receptors.

Leckie C, Chapman KE, Edwards CR, Seckl JR.

Endocrinology. 1995 Dec;136(12):5561-9.

PMID:
7588309
[PubMed - indexed for MEDLINE]
10.

The intracellular localization of the mineralocorticoid receptor is regulated by 11beta-hydroxysteroid dehydrogenase type 2.

Odermatt A, Arnold P, Frey FJ.

J Biol Chem. 2001 Jul 27;276(30):28484-92. Epub 2001 May 11.

PMID:
11350956
[PubMed - indexed for MEDLINE]
Free Article
11.

[Genetic disorders caused by gain or loss of function of the mineralocorticoid receptor].

Arai K, Shibasaki T.

Nihon Rinsho. 2002 Feb;60(2):361-6. Review. Japanese.

PMID:
11857927
[PubMed - indexed for MEDLINE]
12.

Stimulation of testosterone production in rat Leydig cells by aldosterone is mineralocorticoid receptor mediated.

Ge RS, Dong Q, Sottas CM, Latif SA, Morris DJ, Hardy MP.

Mol Cell Endocrinol. 2005 Nov 24;243(1-2):35-42. Epub 2005 Sep 26.

PMID:
16188378
[PubMed - indexed for MEDLINE]
13.

Analysis of the S810L point mutation of the mineralocorticoid receptor in patients with pregnancy-induced hypertension.

Schmider-Ross A, Wirsing M, Büscher U, Neitzel H, Krause M, Henrich W, Reles A, Dudenhausen JW.

Hypertens Pregnancy. 2004;23(1):113-9.

PMID:
15117605
[PubMed - indexed for MEDLINE]
14.

Interrelations between binding affinity and metabolic clearance rate for the main corticosteroids in the rabbit.

Daniel JY, Leboulenger F, Vaudry H, Floch HH, Assenmacher I.

J Steroid Biochem. 1982 Mar;16(3):379-84.

PMID:
7087466
[PubMed - indexed for MEDLINE]
15.

A novel missense mutation, F826Y, in the mineralocorticoid receptor gene in Japanese hypertensives: its implications for clinical phenotypes.

Kamide K, Yang J, Kokubo Y, Takiuchi S, Miwa Y, Horio T, Tanaka C, Banno M, Nagura J, Okayama A, Tomoike H, Kawano Y, Miyata T.

Hypertens Res. 2005 Sep;28(9):703-9.

PMID:
16419642
[PubMed - indexed for MEDLINE]
16.

Mineralocorticoid versus glucocorticoid receptor occupancy mediating aldosterone-stimulated sodium transport in a novel renal cell line.

Gaeggeler HP, Gonzalez-Rodriguez E, Jaeger NF, Loffing-Cueni D, Norregaard R, Loffing J, Horisberger JD, Rossier BC.

J Am Soc Nephrol. 2005 Apr;16(4):878-91. Epub 2005 Mar 2.

PMID:
15743993
[PubMed - indexed for MEDLINE]
Free Article
17.

Translational research goes both ways: lessons from clinical studies.

Funder JW.

Clin Exp Pharmacol Physiol. 2008 Apr;35(4):526-9. doi: 10.1111/j.1440-1681.2008.04910.x.

PMID:
18307755
[PubMed - indexed for MEDLINE]
18.

Characterization of steroid receptors in the gut and kidney of the frog (Rana catesbeiana) and in the gut of the turtle (Chrysemys picta).

Mehi AZ, DiBattista JA, Sandor T.

J Steroid Biochem. 1987 May;26(5):627-39.

PMID:
3035288
[PubMed - indexed for MEDLINE]
19.

19-nor analogs of adrenal steroids: mineralocorticoid and glucocorticoid receptor activity.

Wynne KN, Mercer J, Stockigt JR, Funder JW.

Endocrinology. 1980 Nov;107(5):1278-80.

PMID:
6253261
[PubMed - indexed for MEDLINE]
20.

Binding characteristics of mineralocorticoid and glucocorticoid receptors in dog brain and pituitary.

Reul JM, de Kloet ER, van Sluijs FJ, Rijnberk A, Rothuizen J.

Endocrinology. 1990 Aug;127(2):907-15.

PMID:
2164924
[PubMed - indexed for MEDLINE]
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