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Long-lasting occupancy of central nicotinic acetylcholine receptors after smoking: a PET study in monkeys.

Valette H, Bottlaender M, Dollé F, Coulon C, Ottaviani M, Syrota A.

J Neurochem. 2003 Jan;84(1):105-11.


In vivo imaging of human cerebral nicotinic acetylcholine receptors with 2-18F-fluoro-A-85380 and PET.

Gallezot JD, Bottlaender M, Grégoire MC, Roumenov D, Deverre JR, Coulon C, Ottaviani M, Dollé F, Syrota A, Valette H.

J Nucl Med. 2005 Feb;46(2):240-7.


Brain nicotinic acetylcholine receptor occupancy: effect of smoking a denicotinized cigarette.

Brody AL, Mandelkern MA, Costello MR, Abrams AL, Scheibal D, Farahi J, London ED, Olmstead RE, Rose JE, Mukhin AG.

Int J Neuropsychopharmacol. 2009 Apr;12(3):305-16. doi: 10.1017/S146114570800922X. Epub 2008 Aug 18.


Imaging nicotinic acetylcholine receptors with fluorine-18-FPH, an epibatidine analog.

Villemagne VL, Horti A, Scheffel U, Ravert HT, Finley P, Clough DJ, London ED, Wagner HN Jr, Dannals RF.

J Nucl Med. 1997 Nov;38(11):1737-41.


Acute inhibition of cardiac monoamine oxidase A after tobacco smoke inhalation: validation study of [11C]befloxatone in rats followed by a positron emission tomography application in baboons.

Valette H, Bottlaender M, Dollé F, Coulon C, Ottaviani M, Syrota A.

J Pharmacol Exp Ther. 2005 Jul;314(1):431-6. Epub 2005 Apr 15.


Evaluation of 5-(11)C-methyl-A-85380 as an imaging agent for PET investigations of brain nicotinic acetylcholine receptors.

Iida Y, Ogawa M, Ueda M, Tominaga A, Kawashima H, Magata Y, Nishiyama S, Tsukada H, Mukai T, Saji H.

J Nucl Med. 2004 May;45(5):878-84.


Characterization of the nicotinic ligand 2-[18F]fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine in vivo.

Valette H, Bottlaender M, Dollé F, Guenther I, Coulon C, Hinnen F, Fuseau C, Ottaviani M, Crouzel C.

Life Sci. 1999;64(5):PL93-7.


Imaging central nicotinic acetylcholine receptors in baboons with [18F]fluoro-A-85380.

Valette H, Bottlaender M, Dollé F, Guenther I, Fuseau C, Coulon C, Ottaviani M, Crouzel C.

J Nucl Med. 1999 Aug;40(8):1374-80.


Cigarette smoking saturates brain alpha 4 beta 2 nicotinic acetylcholine receptors.

Brody AL, Mandelkern MA, London ED, Olmstead RE, Farahi J, Scheibal D, Jou J, Allen V, Tiongson E, Chefer SI, Koren AO, Mukhin AG.

Arch Gen Psychiatry. 2006 Aug;63(8):907-15.


Quantification of smoking-induced occupancy of beta2-nicotinic acetylcholine receptors: estimation of nondisplaceable binding.

Esterlis I, Cosgrove KP, Batis JC, Bois F, Stiklus SM, Perkins E, Seibyl JP, Carson RE, Staley JK.

J Nucl Med. 2010 Aug;51(8):1226-33. doi: 10.2967/jnumed.109.072447. Epub 2010 Jul 21.


Comparative studies of epibatidine derivatives [18F]NFEP and [18F]N-methyl-NFEP: kinetics, nicotine effect, and toxicity.

Ding YS, Molina PE, Fowler JS, Logan J, Volkow ND, Kuhar MJ, Carroll FI.

Nucl Med Biol. 1999 Jan;26(1):139-48.


PET Imaging of nicotinic acetylcholine receptors in baboons with 18F-AZAN, a radioligand with improved brain kinetics.

Kuwabara H, Wong DF, Gao Y, Valentine H, Holt DP, Ravert HT, Dannals RF, Horti AG.

J Nucl Med. 2012 Jan;53(1):121-9. doi: 10.2967/jnumed.111.092338. Epub 2011 Dec 15.


Synthesis of a fluorine-18 labeled derivative of epibatidine for in vivo nicotinic acetylcholine receptor PET imaging.

Dolci L, Dolle F, Valette H, Vaufrey F, Fuseau C, Bottlaender M, Crouzel C.

Bioorg Med Chem. 1999 Mar;7(3):467-79.


PET studies of the uptake of (S)- and (R)-[11C]nicotine in the human brain: difficulties in visualizing specific receptor binding in vivo.

Nybäck H, Halldin C, Ahlin A, Curvall M, Eriksson L.

Psychopharmacology (Berl). 1994 Jun;115(1-2):31-6.


Pharmacological evaluation of a Br-76 analog of epibatidine: a potent ligand for studying brain nicotinic acetylcholine receptors.

Kassiou M, Bottlaender M, Loc'h C, Dolle F, Musachio JL, Coulon C, Ottaviani M, Dannals RF, Maziere B.

Synapse. 2002 Aug;45(2):95-104.


In vivo imaging of nicotinic receptor upregulation following chronic (-)-nicotine treatment in baboon using SPECT.

Kassiou M, Eberl S, Meikle SR, Birrell A, Constable C, Fulham MJ, Wong DF, Musachio JL.

Nucl Med Biol. 2001 Feb;28(2):165-75.


Human tobacco smokers in early abstinence have higher levels of beta2* nicotinic acetylcholine receptors than nonsmokers.

Staley JK, Krishnan-Sarin S, Cosgrove KP, Krantzler E, Frohlich E, Perry E, Dubin JA, Estok K, Brenner E, Baldwin RM, Tamagnan GD, Seibyl JP, Jatlow P, Picciotto MR, London ED, O'Malley S, van Dyck CH.

J Neurosci. 2006 Aug 23;26(34):8707-14.

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