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Results: 1 to 20 of 235

1.

Induction of medulloblastomas in mice by sonic hedgehog, independent of Gli1.

Weiner HL, Bakst R, Hurlbert MS, Ruggiero J, Ahn E, Lee WS, Stephen D, Zagzag D, Joyner AL, Turnbull DH.

Cancer Res. 2002 Nov 15;62(22):6385-9.

PMID:
12438220
[PubMed - indexed for MEDLINE]
Free Article
2.

The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas.

Hallahan AR, Pritchard JI, Hansen S, Benson M, Stoeck J, Hatton BA, Russell TL, Ellenbogen RG, Bernstein ID, Beachy PA, Olson JM.

Cancer Res. 2004 Nov 1;64(21):7794-800.

PMID:
15520185
[PubMed - indexed for MEDLINE]
Free Article
3.

Interferon-gamma induced medulloblastoma in the developing cerebellum.

Lin W, Kemper A, McCarthy KD, Pytel P, Wang JP, Campbell IL, Utset MF, Popko B.

J Neurosci. 2004 Nov 10;24(45):10074-83.

PMID:
15537876
[PubMed - indexed for MEDLINE]
Free Article
4.

Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas.

Leung C, Lingbeek M, Shakhova O, Liu J, Tanger E, Saremaslani P, Van Lohuizen M, Marino S.

Nature. 2004 Mar 18;428(6980):337-41.

PMID:
15029199
[PubMed - indexed for MEDLINE]
5.

Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation.

Park HL, Bai C, Platt KA, Matise MP, Beeghly A, Hui CC, Nakashima M, Joyner AL.

Development. 2000 Apr;127(8):1593-605.

PMID:
10725236
[PubMed - indexed for MEDLINE]
Free Article
6.

Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors.

Kenney AM, Cole MD, Rowitch DH.

Development. 2003 Jan;130(1):15-28.

PMID:
12441288
[PubMed - indexed for MEDLINE]
Free Article
7.

N-myc can substitute for insulin-like growth factor signaling in a mouse model of sonic hedgehog-induced medulloblastoma.

Browd SR, Kenney AM, Gottfried ON, Yoon JW, Walterhouse D, Pedone CA, Fults DW.

Cancer Res. 2006 Mar 1;66(5):2666-72.

PMID:
16510586
[PubMed - indexed for MEDLINE]
Free Article
8.

Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling.

Lipinski RJ, Gipp JJ, Zhang J, Doles JD, Bushman W.

Exp Cell Res. 2006 Jul 1;312(11):1925-38. Epub 2006 Mar 29.

PMID:
16571352
[PubMed - indexed for MEDLINE]
9.

Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice.

Rao G, Pedone CA, Del Valle L, Reiss K, Holland EC, Fults DW.

Oncogene. 2004 Aug 12;23(36):6156-62.

PMID:
15195141
[PubMed - indexed for MEDLINE]
10.

c-Myc enhances sonic hedgehog-induced medulloblastoma formation from nestin-expressing neural progenitors in mice.

Rao G, Pedone CA, Coffin CM, Holland EC, Fults DW.

Neoplasia. 2003 May-Jun;5(3):198-204.

PMID:
12869303
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Gli1 is important for medulloblastoma formation in Ptc1+/- mice.

Kimura H, Stephen D, Joyner A, Curran T.

Oncogene. 2005 Jun 9;24(25):4026-36.

PMID:
15806168
[PubMed - indexed for MEDLINE]
12.

Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation.

Lamm ML, Catbagan WS, Laciak RJ, Barnett DH, Hebner CM, Gaffield W, Walterhouse D, Iannaccone P, Bushman W.

Dev Biol. 2002 Sep 15;249(2):349-66.

PMID:
12221011
[PubMed - indexed for MEDLINE]
Free Article
13.

Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors.

Oliver TG, Grasfeder LL, Carroll AL, Kaiser C, Gillingham CL, Lin SM, Wickramasinghe R, Scott MP, Wechsler-Reya RJ.

Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7331-6. Epub 2003 May 30.

PMID:
12777630
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Apoptosis suppression by somatic cell transfer of Bcl-2 promotes Sonic hedgehog-dependent medulloblastoma formation in mice.

McCall TD, Pedone CA, Fults DW.

Cancer Res. 2007 Jun 1;67(11):5179-85.

PMID:
17545597
[PubMed - indexed for MEDLINE]
Free Article
15.

YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation.

Fernandez-L A, Northcott PA, Dalton J, Fraga C, Ellison D, Angers S, Taylor MD, Kenney AM.

Genes Dev. 2009 Dec 1;23(23):2729-41. doi: 10.1101/gad.1824509.

PMID:
19952108
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours.

Dahmane N, Lee J, Robins P, Heller P, Ruiz i Altaba A.

Nature. 1997 Oct 23;389(6653):876-81. Erratum in: Nature 1997 Dec 4;390(6659):536.

PMID:
9349822
[PubMed - indexed for MEDLINE]
17.

Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3.

Dai P, Akimaru H, Tanaka Y, Maekawa T, Nakafuku M, Ishii S.

J Biol Chem. 1999 Mar 19;274(12):8143-52.

PMID:
10075717
[PubMed - indexed for MEDLINE]
Free Article
18.

The normal patched allele is expressed in medulloblastomas from mice with heterozygous germ-line mutation of patched.

Wetmore C, Eberhart DE, Curran T.

Cancer Res. 2000 Apr 15;60(8):2239-46.

PMID:
10786690
[PubMed - indexed for MEDLINE]
Free Article
19.

Sonic Hedgehog-dependent proliferation in a series of patients with colorectal cancer.

Douard R, Moutereau S, Pernet P, Chimingqi M, Allory Y, Manivet P, Conti M, Vaubourdolle M, Cugnenc PH, Loric S.

Surgery. 2006 May;139(5):665-70.

PMID:
16701100
[PubMed - indexed for MEDLINE]
20.

Expression of sonic hedgehog, patched, and Gli1 in developing taste papillae of the mouse.

Hall JM, Hooper JE, Finger TE.

J Comp Neurol. 1999 Apr 5;406(2):143-55.

PMID:
10096602
[PubMed - indexed for MEDLINE]

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