Similar articles for PMID: 12414812

Year	Number of Results
1997	2
1998	4
1999	9
2000	12
2001	21
2002	18
2003	23
2004	17
2005	4
2006	9
2007	11
2008	10
2009	12
2010	8
2011	10
2012	8
2013	7
2014	12
2015	5
2016	2
2017	3
2018	3
2019	3
2020	6
2021	9
2022	14
2023	6
2024	2

1

Aplidin induces apoptosis in human cancer cells via glutathione depletion and sustained activation of the epidermal growth factor receptor, Src, JNK, and p38 MAPK.

Cuadrado A, Garcia-Fernandez LF, Gonzalez L, Suarez Y, Losada A, Alcaide V, Martinez T, Fernandez-Sousa JM, Sanchez-Puelles JM, Munoz A. Cuadrado A, et al. J Biol Chem. 2003 Jan 3;278(1):241-50. doi: 10.1074/jbc.M201010200. Epub 2002 Oct 31. J Biol Chem. 2003. PMID: 12414812 Free article.

2

Aplidin induces the mitochondrial apoptotic pathway via oxidative stress-mediated JNK and p38 activation and protein kinase C delta.

García-Fernández LF, Losada A, Alcaide V, Alvarez AM, Cuadrado A, González L, Nakayama K, Nakayama KI, Fernández-Sousa JM, Muñoz A, Sánchez-Puelles JM. García-Fernández LF, et al. Oncogene. 2002 Oct 24;21(49):7533-44. doi: 10.1038/sj.onc.1205972. Oncogene. 2002. PMID: 12386816

3

JNK activation is critical for Aplidin-induced apoptosis.

Cuadrado A, González L, Suárez Y, Martínez T, Muñoz A. Cuadrado A, et al. Oncogene. 2004 Jun 10;23(27):4673-80. doi: 10.1038/sj.onc.1207636. Oncogene. 2004. PMID: 15122339

4

Aplidin induces JNK-dependent apoptosis in human breast cancer cells via alteration of glutathione homeostasis, Rac1 GTPase activation, and MKP-1 phosphatase downregulation.

González-Santiago L, Suárez Y, Zarich N, Muñoz-Alonso MJ, Cuadrado A, Martínez T, Goya L, Iradi A, Sáez-Tormo G, Maier JV, Moorthy A, Cato AC, Rojas JM, Muñoz A. González-Santiago L, et al. Cell Death Differ. 2006 Nov;13(11):1968-81. doi: 10.1038/sj.cdd.4401898. Epub 2006 Mar 17. Cell Death Differ. 2006. PMID: 16543941

5

Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU145 cells: possible role in antiproliferation and apoptosis.

Tyagi A, Agarwal R, Agarwal C. Tyagi A, et al. Oncogene. 2003 Mar 6;22(9):1302-16. doi: 10.1038/sj.onc.1206265. Oncogene. 2003. PMID: 12618755

6

Sustained mitogen-activated protein kinase activation is induced by transforming erbB receptor complexes.

Wu CJ, Qian X, O'Rourke DM. Wu CJ, et al. DNA Cell Biol. 1999 Oct;18(10):731-41. doi: 10.1089/104454999314872. DNA Cell Biol. 1999. PMID: 10541432

7

Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death.

Dent P, Reardon DB, Park JS, Bowers G, Logsdon C, Valerie K, Schmidt-Ullrich R. Dent P, et al. Mol Biol Cell. 1999 Aug;10(8):2493-506. doi: 10.1091/mbc.10.8.2493. Mol Biol Cell. 1999. PMID: 10436007 Free PMC article.

8

JNK (c-Jun N-terminal kinase) and p38 activation in receptor-mediated and chemically-induced apoptosis of T-cells: differential requirements for caspase activation.

MacFarlane M, Cohen GM, Dickens M. MacFarlane M, et al. Biochem J. 2000 May 15;348 Pt 1(Pt 1):93-101. Biochem J. 2000. PMID: 10794718 Free PMC article.

9

Relevance of mitogen activated protein kinase (MAPK) and phosphotidylinositol-3-kinase/protein kinase B (PI3K/PKB) pathways to induction of apoptosis by curcumin in breast cells.

Squires MS, Hudson EA, Howells L, Sale S, Houghton CE, Jones JL, Fox LH, Dickens M, Prigent SA, Manson MM. Squires MS, et al. Biochem Pharmacol. 2003 Feb 1;65(3):361-76. doi: 10.1016/s0006-2952(02)01517-4. Biochem Pharmacol. 2003. PMID: 12527329

10

[The role of mitogen-activated protein kinase cascades in inhibition of proliferation in human prostate carcinoma cells by raloxifene: an in vitro experiment].

Zhang YX, Kong CZ. Zhang YX, et al. Zhonghua Yi Xue Za Zhi. 2008 Jan 22;88(4):271-5. Zhonghua Yi Xue Za Zhi. 2008. PMID: 18361842 Chinese.

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