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Items: 1 to 20 of 102


Yersinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression.

Sing A, Rost D, Tvardovskaia N, Roggenkamp A, Wiedemann A, Kirschning CJ, Aepfelbacher M, Heesemann J.

J Exp Med. 2002 Oct 21;196(8):1017-24.


Contribution of toll-like receptors 2 and 4 in an oral Yersinia enterocolitica mouse infection model.

Sing A, Tvardovskaia N, Rost D, Kirschning CJ, Wagner H, Heesemann J.

Int J Med Microbiol. 2003 Nov;293(5):341-8.


A hypervariable N-terminal region of Yersinia LcrV determines Toll-like receptor 2-mediated IL-10 induction and mouse virulence.

Sing A, Reithmeier-Rost D, Granfors K, Hill J, Roggenkamp A, Heesemann J.

Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):16049-54. Epub 2005 Oct 20.


Yersinia V antigen induces both TLR homo- and heterotolerance in an IL-10-involving manner.

Reithmeier-Rost D, Bierschenk S, Filippova N, Schröder-Braunstein J, Sing A.

Cell Immunol. 2004 Sep-Oct;231(1-2):63-74. Epub 2005 Jan 7.


Attachment of LcrV from Yersinia pestis at dual binding sites to human TLR-2 and human IFN-gamma receptor.

Abramov VM, Khlebnikov VS, Vasiliev AM, Kosarev IV, Vasilenko RN, Kulikova NL, Khodyakova AV, Evstigneev VI, Uversky VN, Motin VL, Smirnov GB, Brubaker RR.

J Proteome Res. 2007 Jun;6(6):2222-31. Epub 2007 Apr 19.


The weak interaction of LcrV and TLR2 does not contribute to the virulence of Yersinia pestis.

Reithmeier-Rost D, Hill J, Elvin SJ, Williamson D, Dittmann S, Schmid A, Wilharm G, Sing A.

Microbes Infect. 2007 Jul;9(8):997-1002. Epub 2007 Apr 12.


Evaluation of the role of LcrV-Toll-like receptor 2-mediated immunomodulation in the virulence of Yersinia pestis.

Pouliot K, Pan N, Wang S, Lu S, Lien E, Goguen JD.

Infect Immun. 2007 Jul;75(7):3571-80. Epub 2007 Apr 16.


Passive immunity to infection with Yersinia spp. mediated by anti-recombinant V antigen is dependent on polymorphism of V antigen.

Roggenkamp A, Geiger AM, Leitritz L, Kessler A, Heesemann J.

Infect Immun. 1997 Feb;65(2):446-51.


A dominant role of Toll-like receptor 4 in the signaling of apoptosis in bacteria-faced macrophages.

Haase R, Kirschning CJ, Sing A, Schröttner P, Fukase K, Kusumoto S, Wagner H, Heesemann J, Ruckdeschel K.

J Immunol. 2003 Oct 15;171(8):4294-303.


Amino acid substitutions in LcrV at putative sites of interaction with Toll-like receptor 2 do not affect the virulence of Yersinia pestis.

Sun W, Curtiss R 3rd.

Microb Pathog. 2012 Nov-Dec;53(5-6):198-206. doi: 10.1016/j.micpath.2012.07.003. Epub 2012 Jul 24.


Prevention and treatment of colitis with Lactococcus lactis secreting the immunomodulatory Yersinia LcrV protein.

Foligne B, Dessein R, Marceau M, Poiret S, Chamaillard M, Pot B, Simonet M, Daniel C.

Gastroenterology. 2007 Sep;133(3):862-74. Epub 2007 Jun 20.


The CD14 ligands lipoarabinomannan and lipopolysaccharide differ in their requirement for Toll-like receptors.

Means TK, Lien E, Yoshimura A, Wang S, Golenbock DT, Fenton MJ.

J Immunol. 1999 Dec 15;163(12):6748-55.


Mycoplasma fermentans lipoprotein M161Ag-induced cell activation is mediated by Toll-like receptor 2: role of N-terminal hydrophobic portion in its multiple functions.

Nishiguchi M, Matsumoto M, Takao T, Hoshino M, Shimonishi Y, Tsuji S, Begum NA, Takeuchi O, Akira S, Toyoshima K, Seya T.

J Immunol. 2001 Feb 15;166(4):2610-6.


Involvement of lipopolysaccharide binding protein, CD14, and Toll-like receptors in the initiation of innate immune responses by Treponema glycolipids.

Schröder NW, Opitz B, Lamping N, Michelsen KS, Zähringer U, Göbel UB, Schumann RR.

J Immunol. 2000 Sep 1;165(5):2683-93.


Mechanisms of Yersinia enterocolitica evasion of the host innate immune response by V antigen.

Sing A, Rost D, Tvardovskaia N, Roggenkamp A, Geiger AM, Kirschning CJ, Wiedemann A, Aepfelbacher M, Heesemann J.

Adv Exp Med Biol. 2003;529:165-7. No abstract available.


Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.

Takeuchi O, Hoshino K, Kawai T, Sanjo H, Takada H, Ogawa T, Takeda K, Akira S.

Immunity. 1999 Oct;11(4):443-51.

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