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Results: 1 to 20 of 124

1.

Regulation of WNK1 by an autoinhibitory domain and autophosphorylation.

Xu BE, Min X, Stippec S, Lee BH, Goldsmith EJ, Cobb MH.

J Biol Chem. 2002 Dec 13;277(50):48456-62. Epub 2002 Oct 8.

PMID:
12374799
[PubMed - indexed for MEDLINE]
Free Article
2.

Properties of WNK1 and implications for other family members.

Lenertz LY, Lee BH, Min X, Xu BE, Wedin K, Earnest S, Goldsmith EJ, Cobb MH.

J Biol Chem. 2005 Jul 22;280(29):26653-8. Epub 2005 May 9.

PMID:
15883153
[PubMed - indexed for MEDLINE]
Free Article
3.

WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II.

Xu B, English JM, Wilsbacher JL, Stippec S, Goldsmith EJ, Cobb MH.

J Biol Chem. 2000 Jun 2;275(22):16795-801.

PMID:
10828064
[PubMed - indexed for MEDLINE]
Free Article
4.

The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases.

Vitari AC, Deak M, Morrice NA, Alessi DR.

Biochem J. 2005 Oct 1;391(Pt 1):17-24.

PMID:
16083423
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Mass spectrometry and site-directed mutagenesis identify several autophosphorylated residues required for the activity of PrkC, a Ser/Thr kinase from Bacillus subtilis.

Madec E, Stensballe A, Kjellström S, Cladière L, Obuchowski M, Jensen ON, Séror SJ.

J Mol Biol. 2003 Jul 11;330(3):459-72.

PMID:
12842463
[PubMed - indexed for MEDLINE]
6.

Mutational analysis of the regulatory mechanism of PKN: the regulatory region of PKN contains an arachidonic acid-sensitive autoinhibitory domain.

Yoshinaga C, Mukai H, Toshimori M, Miyamoto M, Ono Y.

J Biochem. 1999 Sep;126(3):475-84.

PMID:
10467162
[PubMed - indexed for MEDLINE]
Free Article
7.

Identification of an autoinhibitory domain of p21-activated protein kinase 5.

Ching YP, Leong VY, Wong CM, Kung HF.

J Biol Chem. 2003 Sep 5;278(36):33621-4. Epub 2003 Jul 14.

PMID:
12860998
[PubMed - indexed for MEDLINE]
Free Article
8.

Comparison of WNK4 and WNK1 kinase and inhibiting activities.

Wang Z, Yang CL, Ellison DH.

Biochem Biophys Res Commun. 2004 May 7;317(3):939-44.

PMID:
15081430
[PubMed - indexed for MEDLINE]
9.
10.

Biochemical properties of the autophosphorylation of RLK5, a receptor-like protein kinase from Arabidopsis thaliana.

Horn MA, Walker JC.

Biochim Biophys Acta. 1994 Sep 21;1208(1):65-74.

PMID:
8086440
[PubMed - indexed for MEDLINE]
11.

Molecular characterization of functional domains in the protein kinase SOS2 that is required for plant salt tolerance.

Guo Y, Halfter U, Ishitani M, Zhu JK.

Plant Cell. 2001 Jun;13(6):1383-400.

PMID:
11402167
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Characterization of an autoinhibitory domain in human mitogen-activated protein kinase-activated protein kinase 2.

Zu YL, Ai Y, Huang CK.

J Biol Chem. 1995 Jan 6;270(1):202-6.

PMID:
7814374
[PubMed - indexed for MEDLINE]
Free Article
13.

WNK lies upstream of kinases involved in regulation of ion transporters.

Gamba G.

Biochem J. 2005 Oct 1;391(Pt 1):e1-3.

PMID:
16173916
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Regulation of the interaction of Pak2 with Cdc42 via autophosphorylation of serine 141.

Jung JH, Traugh JA.

J Biol Chem. 2005 Dec 2;280(48):40025-31. Epub 2005 Oct 4.

PMID:
16204230
[PubMed - indexed for MEDLINE]
Free Article
15.

Solution structure of the WNK1 autoinhibitory domain, a WNK-specific PF2 domain.

Moon TM, Correa F, Kinch LN, Piala AT, Gardner KH, Goldsmith EJ.

J Mol Biol. 2013 Apr 26;425(8):1245-52. doi: 10.1016/j.jmb.2013.01.031. Epub 2013 Jan 30.

PMID:
23376100
[PubMed - indexed for MEDLINE]
16.

Intersectin links WNK kinases to endocytosis of ROMK1.

He G, Wang HR, Huang SK, Huang CL.

J Clin Invest. 2007 Apr;117(4):1078-87. Epub 2007 Mar 22.

PMID:
17380208
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop trans-autophosphorylation.

Thastrup JO, Rafiqi FH, Vitari AC, Pozo-Guisado E, Deak M, Mehellou Y, Alessi DR.

Biochem J. 2012 Jan 1;441(1):325-37. doi: 10.1042/BJ20111879.

PMID:
22032326
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Substrates enhance autophosphorylation and activation of p21-activated protein kinase gamma-PAK in the absence of activation loop phosphorylation.

Jakobi R, Huang Z, Walter BN, Tuazon PT, Traugh JA.

Eur J Biochem. 2000 Jul;267(14):4414-21.

PMID:
10880965
[PubMed - indexed for MEDLINE]
Free Article
19.

Lack of constitutive activity of the free kinase domain of protein kinase C zeta. Dependence on transphosphorylation of the activation loop.

Smith L, Smith JB.

J Biol Chem. 2002 Nov 29;277(48):45866-73. Epub 2002 Sep 19.

PMID:
12244101
[PubMed - indexed for MEDLINE]
Free Article
20.

A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases.

Pirruccello M, Sondermann H, Pelton JG, Pellicena P, Hoelz A, Chernoff J, Wemmer DE, Kuriyan J.

J Mol Biol. 2006 Aug 11;361(2):312-26. Epub 2006 Jun 27.

PMID:
16837009
[PubMed - indexed for MEDLINE]

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