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Items: 1 to 20 of 92

1.
2.

p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells.

Balasenthil S, Sahin AA, Barnes CJ, Wang RA, Pestell RG, Vadlamudi RK, Kumar R.

J Biol Chem. 2004 Jan 9;279(2):1422-8. Epub 2003 Oct 6.

3.

Estrogen regulation of Pak1 and FKHR pathways in breast cancer cells.

Mazumdar A, Kumar R.

FEBS Lett. 2003 Jan 30;535(1-3):6-10.

4.

P21-activated kinase 1 regulation of estrogen receptor-alpha activation involves serine 305 activation linked with serine 118 phosphorylation.

Rayala SK, Talukder AH, Balasenthil S, Tharakan R, Barnes CJ, Wang RA, Aldaz CM, Khan S, Kumar R.

Cancer Res. 2006 Feb 1;66(3):1694-701.

5.

PAK1 hyperactivation is sufficient for mammary gland tumor formation.

Wang RA, Zhang H, Balasenthil S, Medina D, Kumar R.

Oncogene. 2006 May 11;25(20):2931-6.

PMID:
16331248
6.

Estrogen receptor activation at serine 305 is sufficient to upregulate cyclin D1 in breast cancer cells.

Balasenthil S, Barnes CJ, Rayala SK, Kumar R.

FEBS Lett. 2004 Jun 4;567(2-3):243-7.

7.

Essential functions of p21-activated kinase 1 in morphogenesis and differentiation of mammary glands.

Wang RA, Vadlamudi RK, Bagheri-Yarmand R, Beuvink I, Hynes NE, Kumar R.

J Cell Biol. 2003 May 12;161(3):583-92. Epub 2003 May 5.

8.

CRIPak, a novel endogenous Pak1 inhibitor.

Talukder AH, Meng Q, Kumar R.

Oncogene. 2006 Mar 2;25(9):1311-9.

PMID:
16278681
9.

MICoA, a novel metastasis-associated protein 1 (MTA1) interacting protein coactivator, regulates estrogen receptor-alpha transactivation functions.

Mishra SK, Mazumdar A, Vadlamudi RK, Li F, Wang RA, Yu W, Jordan VC, Santen RJ, Kumar R.

J Biol Chem. 2003 May 23;278(21):19209-19. Epub 2003 Mar 14.

10.

Sliding p21-activated kinase 1 to nucleus impacts tamoxifen sensitivity.

Rayala SK, Kumar R.

Biomed Pharmacother. 2007 Aug;61(7):408-11. Epub 2007 Jun 12. Review.

PMID:
17604944
11.

Estrogen receptor-alpha phosphorylation at serine 305, nuclear p21-activated kinase 1 expression, and response to tamoxifen in postmenopausal breast cancer.

Bostner J, Skoog L, Fornander T, Nordenskjöld B, Stål O.

Clin Cancer Res. 2010 Mar 1;16(5):1624-33. doi: 10.1158/1078-0432.CCR-09-1733. Epub 2010 Feb 23.

12.

Serine 28 phosphorylation of NRIF3 confers its co-activator function for estrogen receptor-alpha transactivation.

Talukder AH, Li DQ, Manavathi B, Kumar R.

Oncogene. 2008 Sep 4;27(39):5233-42. doi: 10.1038/onc.2008.151. Epub 2008 Jun 2.

13.

Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1.

Vadlamudi RK, Li F, Adam L, Nguyen D, Ohta Y, Stossel TP, Kumar R.

Nat Cell Biol. 2002 Sep;4(9):681-90.

PMID:
12198493
14.
15.

Targeted expression of activated Rac3 in mammary epithelium leads to defective postlactational involution and benign mammary gland lesions.

Leung K, Nagy A, Gonzalez-Gomez I, Groffen J, Heisterkamp N, Kaartinen V.

Cells Tissues Organs. 2003;175(2):72-83.

PMID:
14605486
16.

Angiotensin II-induced activation of p21-activated kinase 1 requires Ca2+ and protein kinase C{delta} in vascular smooth muscle cells.

Woolfolk EA, Eguchi S, Ohtsu H, Nakashima H, Ueno H, Gerthoffer WT, Motley ED.

Am J Physiol Cell Physiol. 2005 Nov;289(5):C1286-94. Epub 2005 Jul 20.

17.

Etk/Bmx tyrosine kinase activates Pak1 and regulates tumorigenicity of breast cancer cells.

Bagheri-Yarmand R, Mandal M, Taludker AH, Wang RA, Vadlamudi RK, Kung HJ, Kumar R.

J Biol Chem. 2001 Aug 3;276(31):29403-9. Epub 2001 May 29.

18.

Mechanistic differences in the activation of estrogen receptor-alpha (ER alpha)- and ER beta-dependent gene expression by cAMP signaling pathway(s).

Coleman KM, Dutertre M, El-Gharbawy A, Rowan BG, Weigel NL, Smith CL.

J Biol Chem. 2003 Apr 11;278(15):12834-45. Epub 2003 Jan 31.

19.

Cell cycle-regulated phosphorylation of p21-activated kinase 1.

Thiel DA, Reeder MK, Pfaff A, Coleman TR, Sells MA, Chernoff J.

Curr Biol. 2002 Jul 23;12(14):1227-32.

20.
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