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Results: 1 to 20 of 245

1.

4-1BB co-stimulation enhances human CD8(+) T cell priming by augmenting the proliferation and survival of effector CD8(+) T cells.

Laderach D, Movassagh M, Johnson A, Mittler RS, Galy A.

Int Immunol. 2002 Oct;14(10):1155-67.

PMID:
12356681
[PubMed - indexed for MEDLINE]
Free Article
2.
3.

4-1BB ligand induces cell division, sustains survival, and enhances effector function of CD4 and CD8 T cells with similar efficacy.

Cannons JL, Lau P, Ghumman B, DeBenedette MA, Yagita H, Okumura K, Watts TH.

J Immunol. 2001 Aug 1;167(3):1313-24.

PMID:
11466348
[PubMed - indexed for MEDLINE]
Free Article
4.

During viral infection of the respiratory tract, CD27, 4-1BB, and OX40 collectively determine formation of CD8+ memory T cells and their capacity for secondary expansion.

Hendriks J, Xiao Y, Rossen JW, van der Sluijs KF, Sugamura K, Ishii N, Borst J.

J Immunol. 2005 Aug 1;175(3):1665-76.

PMID:
16034107
[PubMed - indexed for MEDLINE]
Free Article
5.

IL-15-dependent induction of 4-1BB promotes antigen-independent CD8 memory T cell survival.

Pulle G, Vidric M, Watts TH.

J Immunol. 2006 Mar 1;176(5):2739-48.

PMID:
16493029
[PubMed - indexed for MEDLINE]
Free Article
6.

New insights into the role of 4-1BB in immune responses: beyond CD8+ T cells.

Kwon B, Lee HW, Kwon BS.

Trends Immunol. 2002 Aug;23(8):378-80.

PMID:
12133793
[PubMed - indexed for MEDLINE]
7.

Modulation of cord blood CD8+ T-cell effector differentiation by TGF-beta1 and 4-1BB costimulation.

Kim YJ, Stringfield TM, Chen Y, Broxmeyer HE.

Blood. 2005 Jan 1;105(1):274-81. Epub 2004 Sep 7.

PMID:
15353478
[PubMed - indexed for MEDLINE]
Free Article
8.

Analysis of expression and function of the costimulatory molecule 4-1BB in alloimmune responses.

Tan JT, Ha J, Cho HR, Tucker-Burden C, Hendrix RC, Mittler RS, Pearson TC, Larsen CP.

Transplantation. 2000 Jul 15;70(1):175-83.

PMID:
10919597
[PubMed - indexed for MEDLINE]
9.

4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses.

Shuford WW, Klussman K, Tritchler DD, Loo DT, Chalupny J, Siadak AW, Brown TJ, Emswiler J, Raecho H, Larsen CP, Pearson TC, Ledbetter JA, Aruffo A, Mittler RS.

J Exp Med. 1997 Jul 7;186(1):47-55.

PMID:
9206996
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Role of 4-1BB (CD137) in the functional activation of cord blood CD28(-)CD8(+) T cells.

Kim YJ, Brutkiewicz RR, Broxmeyer HE.

Blood. 2002 Nov 1;100(9):3253-60.

PMID:
12384425
[PubMed - indexed for MEDLINE]
Free Article
11.

A switch in costimulation from CD28 to 4-1BB during primary versus secondary CD8 T cell response to influenza in vivo.

Bertram EM, Dawicki W, Sedgmen B, Bramson JL, Lynch DH, Watts TH.

J Immunol. 2004 Jan 15;172(2):981-8.

PMID:
14707071
[PubMed - indexed for MEDLINE]
Free Article
12.

Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells.

Futagawa T, Akiba H, Kodama T, Takeda K, Hosoda Y, Yagita H, Okumura K.

Int Immunol. 2002 Mar;14(3):275-86.

PMID:
11867564
[PubMed - indexed for MEDLINE]
Free Article
13.

4-1BB and OX40 act independently to facilitate robust CD8 and CD4 recall responses.

Dawicki W, Bertram EM, Sharpe AH, Watts TH.

J Immunol. 2004 Nov 15;173(10):5944-51.

PMID:
15528328
[PubMed - indexed for MEDLINE]
Free Article
14.

4-1BB (CD137) controls the clonal expansion and survival of CD8 T cells in vivo but does not contribute to the development of cytotoxicity.

Cooper D, Bansal-Pakala P, Croft M.

Eur J Immunol. 2002 Feb;32(2):521-9.

PMID:
11828369
[PubMed - indexed for MEDLINE]
15.

In vivo triggering through 4-1BB enables Th-independent priming of CTL in the presence of an intact CD28 costimulatory pathway.

Diehl L, van Mierlo GJ, den Boer AT, van der Voort E, Fransen M, van Bostelen L, Krimpenfort P, Melief CJ, Mittler R, Toes RE, Offringa R.

J Immunol. 2002 Apr 15;168(8):3755-62.

PMID:
11937526
[PubMed - indexed for MEDLINE]
Free Article
17.

A novel adenovirus expressing human 4-1BB ligand enhances antitumor immunity.

Yoshida H, Katayose Y, Unno M, Suzuki M, Kodama H, Takemura S, Asano R, Hayashi H, Yamamoto K, Matsuno S, Kudo T.

Cancer Immunol Immunother. 2003 Feb;52(2):97-106. Epub 2003 Jan 18.

PMID:
12594573
[PubMed - indexed for MEDLINE]
18.

Differential clonal expansion of CD4 and CD8 T cells in response to 4-1BB ligation: contribution of 4-1BB during inflammatory responses.

Takahashi C, Mittler RS, Vella AT.

Immunol Lett. 2001 Apr 2;76(3):183-91.

PMID:
11306146
[PubMed - indexed for MEDLINE]
19.

Anti-4-1BB monoclonal antibody enhances rejection of large tumor burden by promoting survival but not clonal expansion of tumor-specific CD8+ T cells.

May KF Jr, Chen L, Zheng P, Liu Y.

Cancer Res. 2002 Jun 15;62(12):3459-65.

PMID:
12067989
[PubMed - indexed for MEDLINE]
Free Article
20.

Anti-CD137 antibodies in the treatment of autoimmune disease and cancer.

Mittler RS, Foell J, McCausland M, Strahotin S, Niu L, Bapat A, Hewes LB.

Immunol Res. 2004;29(1-3):197-208. Review.

PMID:
15181282
[PubMed - indexed for MEDLINE]

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