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Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma.

Liyanage UK, Moore TT, Joo HG, Tanaka Y, Herrmann V, Doherty G, Drebin JA, Strasberg SM, Eberlein TJ, Goedegebuure PS, Linehan DC.

J Immunol. 2002 Sep 1;169(5):2756-61.


Depletion of CD4+CD25+ regulatory T cells promotes a tumor-specific immune response in pancreas cancer-bearing mice.

Viehl CT, Moore TT, Liyanage UK, Frey DM, Ehlers JP, Eberlein TJ, Goedegebuure PS, Linehan DC.

Ann Surg Oncol. 2006 Sep;13(9):1252-8. Epub 2006 Sep 3.


Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphoma.

Yang ZZ, Novak AJ, Stenson MJ, Witzig TE, Ansell SM.

Blood. 2006 May 1;107(9):3639-46. Epub 2006 Jan 10.


CD4+/CD25+ regulatory cells inhibit activation of tumor-primed CD4+ T cells with IFN-gamma-dependent antiangiogenic activity, as well as long-lasting tumor immunity elicited by peptide vaccination.

Casares N, Arribillaga L, Sarobe P, Dotor J, Lopez-Diaz de Cerio A, Melero I, Prieto J, Borrás-Cuesta F, Lasarte JJ.

J Immunol. 2003 Dec 1;171(11):5931-9.


Human CD25+ regulatory T cells maintain immune tolerance to nickel in healthy, nonallergic individuals.

Cavani A, Nasorri F, Ottaviani C, Sebastiani S, De Pità O, Girolomoni G.

J Immunol. 2003 Dec 1;171(11):5760-8.


Increased populations of regulatory T cells in peripheral blood and tumor-infiltrating lymphocytes in patients with gastric and esophageal cancers.

Ichihara F, Kono K, Takahashi A, Kawaida H, Sugai H, Fujii H.

Clin Cancer Res. 2003 Oct 1;9(12):4404-8.


Compromised lymphocytes infiltrate hepatocellular carcinoma: the role of T-regulatory cells.

Unitt E, Rushbrook SM, Marshall A, Davies S, Gibbs P, Morris LS, Coleman N, Alexander GJ.

Hepatology. 2005 Apr;41(4):722-30.


CD4+CD25high regulatory cells in human peripheral blood.

Baecher-Allan C, Brown JA, Freeman GJ, Hafler DA.

J Immunol. 2001 Aug 1;167(3):1245-53.


Early events in peripheral regulatory T cell induction via the nasal mucosa.

Unger WW, Hauet-Broere F, Jansen W, van Berkel LA, Kraal G, Samsom JN.

J Immunol. 2003 Nov 1;171(9):4592-603.


Activated but not resting regulatory T cells accumulated in tumor microenvironment and correlated with tumor progression in patients with colorectal cancer.

Lin YC, Mahalingam J, Chiang JM, Su PJ, Chu YY, Lai HY, Fang JH, Huang CT, Chiu CT, Lin CY.

Int J Cancer. 2013 Mar 15;132(6):1341-50. doi: 10.1002/ijc.27784. Epub 2012 Sep 18.


Tumor specific cytolysis by tumor infiltrating lymphocytes in breast cancer.

Baxevanis CN, Dedoussis GV, Papadopoulos NG, Missitzis I, Stathopoulos GP, Papamichail M.

Cancer. 1994 Aug 15;74(4):1275-82.


Activated self-MHC-reactive T cells have the cytokine phenotype of Th3/T regulatory cell 1 T cells.

Kitani A, Chua K, Nakamura K, Strober W.

J Immunol. 2000 Jul 15;165(2):691-702.


CTLA-4 blockade following relapse of malignancy after allogeneic stem cell transplantation is associated with T cell activation but not with increased levels of T regulatory cells.

Zhou J, Bashey A, Zhong R, Corringham S, Messer K, Pu M, Ma W, Chut T, Soiffer R, Mitrovich RC, Lowy I, Ball ED.

Biol Blood Marrow Transplant. 2011 May;17(5):682-92. doi: 10.1016/j.bbmt.2010.08.005. Epub 2010 Aug 14.


Identification of CD8+CD25+Foxp3+ suppressive T cells in colorectal cancer tissue.

Chaput N, Louafi S, Bardier A, Charlotte F, Vaillant JC, Ménégaux F, Rosenzwajg M, Lemoine F, Klatzmann D, Taieb J.

Gut. 2009 Apr;58(4):520-9. doi: 10.1136/gut.2008.158824. Epub 2008 Nov 20.


Increased prevalence of regulatory T cells (Treg) is induced by pancreas adenocarcinoma.

Liyanage UK, Goedegebuure PS, Moore TT, Viehl CT, Moo-Young TA, Larson JW, Frey DM, Ehlers JP, Eberlein TJ, Linehan DC.

J Immunother. 2006 Jul-Aug;29(4):416-24.


Increased number of regulatory T cells (T-regs) in the peripheral blood of patients with Her-2/neu-positive early breast cancer.

Decker T, Fischer G, Bücke W, Bücke P, Stotz F, Grüneberger A, Gropp-Meier M, Wiedemann G, Pfeiffer C, Peschel C, Götze K.

J Cancer Res Clin Oncol. 2012 Nov;138(11):1945-50. doi: 10.1007/s00432-012-1258-3. Epub 2012 Jul 4.

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