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Results: 1 to 20 of 175

1.

Concanamycin A, the specific inhibitor of V-ATPases, binds to the V(o) subunit c.

Huss M, Ingenhorst G, König S, Gassel M, Dröse S, Zeeck A, Altendorf K, Wieczorek H.

J Biol Chem. 2002 Oct 25;277(43):40544-8. Epub 2002 Aug 16.

PMID:
12186879
[PubMed - indexed for MEDLINE]
Free Article
2.

Archazolid and apicularen: novel specific V-ATPase inhibitors.

Huss M, Sasse F, Kunze B, Jansen R, Steinmetz H, Ingenhorst G, Zeeck A, Wieczorek H.

BMC Biochem. 2005 Aug 4;6:13.

PMID:
16080788
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Mutations in subunit C of the vacuolar ATPase confer resistance to bafilomycin and identify a conserved antibiotic binding site.

Bowman BJ, Bowman EJ.

J Biol Chem. 2002 Feb 8;277(6):3965-72. Epub 2001 Nov 27.

PMID:
11724795
[PubMed - indexed for MEDLINE]
Free Article
4.

Semisynthetic derivatives of concanamycin A and C, as inhibitors of V- and P-type ATPases: structure-activity investigations and developments of photoaffinity probes.

Dröse S, Boddien C, Gassel M, Ingenhorst G, Zeeck A, Altendorf K.

Biochemistry. 2001 Mar 6;40(9):2816-25.

PMID:
11258892
[PubMed - indexed for MEDLINE]
5.

Concanamycin and indolyl pentadieneamide inhibitors of the vacuolar H+-ATPase bind with high affinity to the purified proteolipid subunit of the membrane domain.

Whyteside G, Meek PJ, Ball SK, Dixon N, Finbow ME, Kee TP, Findlay JB, Harrison MA.

Biochemistry. 2005 Nov 15;44(45):15024-31.

PMID:
16274249
[PubMed - indexed for MEDLINE]
6.

The binding site of the V-ATPase inhibitor apicularen is in the vicinity of those for bafilomycin and archazolid.

Osteresch C, Bender T, Grond S, von Zezschwitz P, Kunze B, Jansen R, Huss M, Wieczorek H.

J Biol Chem. 2012 Sep 14;287(38):31866-76. doi: 10.1074/jbc.M112.372169. Epub 2012 Jul 19.

PMID:
22815478
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Interaction of inhibitors of the vacuolar H(+)-ATPase with the transmembrane Vo-sector.

Páli T, Whyteside G, Dixon N, Kee TP, Ball S, Harrison MA, Findlay JB, Finbow ME, Marsh D.

Biochemistry. 2004 Sep 28;43(38):12297-305.

PMID:
15379568
[PubMed - indexed for MEDLINE]
8.

Salicylihalamide A inhibits the V0 sector of the V-ATPase through a mechanism distinct from bafilomycin A1.

Xie XS, Padron D, Liao X, Wang J, Roth MG, De Brabander JK.

J Biol Chem. 2004 May 7;279(19):19755-63. Epub 2004 Mar 3.

PMID:
14998996
[PubMed - indexed for MEDLINE]
Free Article
9.

Cellular role of the V-ATPase in Neurospora crassa: analysis of mutants resistant to concanamycin or lacking the catalytic subunit A.

Bowman EJ, Bowman BJ.

J Exp Biol. 2000 Jan;203(Pt 1):97-106. Review.

PMID:
10600678
[PubMed - indexed for MEDLINE]
Free Article
10.

Archazolid A binds to the equatorial region of the c-ring of the vacuolar H+-ATPase.

Bockelmann S, Menche D, Rudolph S, Bender T, Grond S, von Zezschwitz P, Muench SP, Wieczorek H, Huss M.

J Biol Chem. 2010 Dec 3;285(49):38304-14. doi: 10.1074/jbc.M110.137539. Epub 2010 Sep 30.

PMID:
20884613
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The amino-terminal domain of the E subunit of vacuolar H(+)-ATPase (V-ATPase) interacts with the H subunit and is required for V-ATPase function.

Lu M, Vergara S, Zhang L, Holliday LS, Aris J, Gluck SL.

J Biol Chem. 2002 Oct 11;277(41):38409-15. Epub 2002 Aug 5.

PMID:
12163484
[PubMed - indexed for MEDLINE]
Free Article
12.

The bafilomycin/concanamycin binding site in subunit c of the V-ATPases from Neurospora crassa and Saccharomyces cerevisiae.

Bowman EJ, Graham LA, Stevens TH, Bowman BJ.

J Biol Chem. 2004 Aug 6;279(32):33131-8. Epub 2004 Jun 4.

PMID:
15180988
[PubMed - indexed for MEDLINE]
Free Article
13.

Identification of a new chondropsin class of antitumor compound that selectively inhibits V-ATPases.

Bowman EJ, Gustafson KR, Bowman BJ, Boyd MR.

J Biol Chem. 2003 Nov 7;278(45):44147-52. Epub 2003 Aug 27.

PMID:
12944415
[PubMed - indexed for MEDLINE]
Free Article
14.

Binding assays of inhibitors towards selected V-ATPase domains.

Fernandes F, Loura LM, Fedorov A, Dixon N, Kee TP, Prieto M, Hemminga MA.

Biochim Biophys Acta. 2006 Nov;1758(11):1777-86. Epub 2006 Jul 21.

PMID:
16996024
[PubMed - indexed for MEDLINE]
Free Article
15.

Expression, purification, and characterization of subunit E, an essential subunit of the vacuolar ATPase.

Grüber G, Godovac-Zimmermann J, Link TA, Coskun U, Rizzo VF, Betz C, Bailer SM.

Biochem Biophys Res Commun. 2002 Nov 1;298(3):383-91.

PMID:
12413952
[PubMed - indexed for MEDLINE]
16.

The V-ATPase subunit C binds to polymeric F-actin as well as to monomeric G-actin and induces cross-linking of actin filaments.

Vitavska O, Merzendorfer H, Wieczorek H.

J Biol Chem. 2005 Jan 14;280(2):1070-6. Epub 2004 Nov 3.

PMID:
15525650
[PubMed - indexed for MEDLINE]
Free Article
17.

[3H]Bafilomycin as a probe for the transmembrane proton channel of the osteoclast vacuolar H(+)-ATPase.

Mattsson JP, Keeling DJ.

Biochim Biophys Acta. 1996 Apr 3;1280(1):98-106.

PMID:
8634321
[PubMed - indexed for MEDLINE]
Free Article
18.

A novel role for subunit C in mediating binding of the H+-V-ATPase to the actin cytoskeleton.

Vitavska O, Wieczorek H, Merzendorfer H.

J Biol Chem. 2003 May 16;278(20):18499-505. Epub 2003 Feb 25.

PMID:
12606563
[PubMed - indexed for MEDLINE]
Free Article
19.

Nitric oxide production by the vacuolar-type (H+)-ATPase inhibitors bafilomycin A1 and concanamycin A and its possible role in apoptosis in RAW 264.7 cells.

Hong J, Nakano Y, Yokomakura A, Ishihara K, Kim S, Kang YS, Ohuchi K.

J Pharmacol Exp Ther. 2006 Nov;319(2):672-81. Epub 2006 Aug 8.

PMID:
16895977
[PubMed - indexed for MEDLINE]
Free Article
20.

A model for the proteolipid ring and bafilomycin/concanamycin-binding site in the vacuolar ATPase of Neurospora crassa.

Bowman BJ, McCall ME, Baertsch R, Bowman EJ.

J Biol Chem. 2006 Oct 20;281(42):31885-93. Epub 2006 Aug 15.

PMID:
16912037
[PubMed - indexed for MEDLINE]
Free Article

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