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Results: 1 to 20 of 138

1.

Prediction of drug transport through the blood-brain barrier in vivo: a comparison between two in vitro cell models.

Lundquist S, Renftel M, Brillault J, Fenart L, Cecchelli R, Dehouck MP.

Pharm Res. 2002 Jul;19(7):976-81.

PMID:
12180550
[PubMed - indexed for MEDLINE]
2.

In vitro models for the blood-brain barrier.

Garberg P, Ball M, Borg N, Cecchelli R, Fenart L, Hurst RD, Lindmark T, Mabondzo A, Nilsson JE, Raub TJ, Stanimirovic D, Terasaki T, Oberg JO, Osterberg T.

Toxicol In Vitro. 2005 Apr;19(3):299-334.

PMID:
15713540
[PubMed - indexed for MEDLINE]
3.

Relationship between permeability status of the blood-brain barrier and in vitro permeability coefficient of a drug.

Gaillard PJ, de Boer AG.

Eur J Pharm Sci. 2000 Dec;12(2):95-102.

PMID:
11102736
[PubMed - indexed for MEDLINE]
4.

Comparison of brain capillary endothelial cell-based and epithelial (MDCK-MDR1, Caco-2, and VB-Caco-2) cell-based surrogate blood-brain barrier penetration models.

Hellinger E, Veszelka S, Tóth AE, Walter F, Kittel A, Bakk ML, Tihanyi K, Háda V, Nakagawa S, Duy TD, Niwa M, Deli MA, Vastag M.

Eur J Pharm Biopharm. 2012 Oct;82(2):340-51. doi: 10.1016/j.ejpb.2012.07.020. Epub 2012 Aug 11.

PMID:
22906709
[PubMed - indexed for MEDLINE]
5.

Evaluation of drug penetration into the brain: a double study by in vivo imaging with positron emission tomography and using an in vitro model of the human blood-brain barrier.

Josserand V, Pélerin H, de Bruin B, Jego B, Kuhnast B, Hinnen F, Ducongé F, Boisgard R, Beuvon F, Chassoux F, Daumas-Duport C, Ezan E, Dollé F, Mabondzo A, Tavitian B.

J Pharmacol Exp Ther. 2006 Jan;316(1):79-86. Epub 2005 Oct 6.

PMID:
16210395
[PubMed - indexed for MEDLINE]
Free Article
6.

Validation of in vitro cell-based human blood-brain barrier model using clinical positron emission tomography radioligands to predict in vivo human brain penetration.

Mabondzo A, Bottlaender M, Guyot AC, Tsaouin K, Deverre JR, Balimane PV.

Mol Pharm. 2010 Oct 4;7(5):1805-15. doi: 10.1021/mp1002366. Epub 2010 Sep 15.

PMID:
20795735
[PubMed - indexed for MEDLINE]
7.

How well can in vitro brain microcapillary endothelial cell models predict rodent in vivo blood-brain barrier permeability?

Avdeef A.

Eur J Pharm Sci. 2011 Jun 14;43(3):109-24. doi: 10.1016/j.ejps.2011.04.001. Epub 2011 Apr 14.

PMID:
21514381
[PubMed - indexed for MEDLINE]
8.

In vitro blood-brain barrier permeability and cerebral endothelial cell uptake of the neuroprotective nitrone compound NXY-059 in normoxic, hypoxic and ischemic conditions.

Dehouck MP, Cecchelli R, Richard Green A, Renftel M, Lundquist S.

Brain Res. 2002 Nov 15;955(1-2):229-35.

PMID:
12419541
[PubMed - indexed for MEDLINE]
9.

Predicting blood-brain barrier permeability of drugs: evaluation of different in vitro assays.

Lohmann C, Hüwel S, Galla HJ.

J Drug Target. 2002 Jun;10(4):263-76.

PMID:
12164375
[PubMed - indexed for MEDLINE]
10.

A co-culture-based model of human blood-brain barrier: application to active transport of indinavir and in vivo-in vitro correlation.

Megard I, Garrigues A, Orlowski S, Jorajuria S, Clayette P, Ezan E, Mabondzo A.

Brain Res. 2002 Feb 15;927(2):153-67.

PMID:
11821009
[PubMed - indexed for MEDLINE]
11.

Primary porcine brain microvascular endothelial cells: biochemical and functional characterisation as a model for drug transport and targeting.

Smith M, Omidi Y, Gumbleton M.

J Drug Target. 2007 May;15(4):253-68. Erratum in: J Drug Target. 2007 Jul;15(6):454.

PMID:
17487694
[PubMed - indexed for MEDLINE]
12.

Establishment and functional characterization of an in vitro model of the blood-brain barrier, comprising a co-culture of brain capillary endothelial cells and astrocytes.

Gaillard PJ, Voorwinden LH, Nielsen JL, Ivanov A, Atsumi R, Engman H, Ringbom C, de Boer AG, Breimer DD.

Eur J Pharm Sci. 2001 Jan;12(3):215-22.

PMID:
11113640
[PubMed - indexed for MEDLINE]
13.

Astrocytes increase the functional expression of P-glycoprotein in an in vitro model of the blood-brain barrier.

Gaillard PJ, van der Sandt IC, Voorwinden LH, Vu D, Nielsen JL, de Boer AG, Breimer DD.

Pharm Res. 2000 Oct;17(10):1198-205.

PMID:
11145224
[PubMed - indexed for MEDLINE]
14.

Blood-brain barrier biology and methodology.

Pardridge WM.

J Neurovirol. 1999 Dec;5(6):556-69. Review.

PMID:
10602397
[PubMed - indexed for MEDLINE]
15.

Porcine brain microvessel endothelial cells as an in vitro model to predict in vivo blood-brain barrier permeability.

Zhang Y, Li CS, Ye Y, Johnson K, Poe J, Johnson S, Bobrowski W, Garrido R, Madhu C.

Drug Metab Dispos. 2006 Nov;34(11):1935-43. Epub 2006 Aug 8.

PMID:
16896068
[PubMed - indexed for MEDLINE]
Free Article
16.

Similar molecular descriptors determine the in vitro drug permeability in endothelial and epithelial cells.

Hakkarainen JJ, Pajander J, Laitinen R, Suhonen M, Forsberg MM.

Int J Pharm. 2012 Oct 15;436(1-2):426-43. doi: 10.1016/j.ijpharm.2012.06.049. Epub 2012 Jun 29.

PMID:
22750947
[PubMed - indexed for MEDLINE]
17.

Astrocytic contributions to blood-brain barrier (BBB) formation by endothelial cells: a possible use of aortic endothelial cell for in vitro BBB model.

Isobe I, Watanabe T, Yotsuyanagi T, Hazemoto N, Yamagata K, Ueki T, Nakanishi K, Asai K, Kato T.

Neurochem Int. 1996 May-Jun;28(5-6):523-33.

PMID:
8792333
[PubMed - indexed for MEDLINE]
18.

Rat brain endothelial cell lines for the study of blood-brain barrier permeability and transport functions.

Roux F, Couraud PO.

Cell Mol Neurobiol. 2005 Feb;25(1):41-58. Review.

PMID:
15962508
[PubMed - indexed for MEDLINE]
19.

Functional role of adenosine receptor subtypes in the regulation of blood-brain barrier permeability: possible implications for the design of synthetic adenosine derivatives.

Schaddelee MP, Voorwinden HL, van Tilburg EW, Pateman TJ, Ijzerman AP, Danhof M, de Boer AG.

Eur J Pharm Sci. 2003 May;19(1):13-22.

PMID:
12729857
[PubMed - indexed for MEDLINE]
20.

Development of a humanized in vitro blood-brain barrier model to screen for brain penetration of antiepileptic drugs.

Cucullo L, Hossain M, Rapp E, Manders T, Marchi N, Janigro D.

Epilepsia. 2007 Mar;48(3):505-16. Epub 2007 Feb 22.

PMID:
17326793
[PubMed - indexed for MEDLINE]

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