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Results: 1 to 20 of 101

1.

Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity.

Ntambi JM, Miyazaki M, Stoehr JP, Lan H, Kendziorski CM, Yandell BS, Song Y, Cohen P, Friedman JM, Attie AD.

Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11482-6. Epub 2002 Aug 12.

PMID:
12177411
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Reduced adiposity and liver steatosis by stearoyl-CoA desaturase deficiency are independent of peroxisome proliferator-activated receptor-alpha.

Miyazaki M, Dobrzyn A, Sampath H, Lee SH, Man WC, Chu K, Peters JM, Gonzalez FJ, Ntambi JM.

J Biol Chem. 2004 Aug 13;279(33):35017-24. Epub 2004 Jun 4.

PMID:
15180999
[PubMed - indexed for MEDLINE]
Free Article
3.

Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase-1.

Jiang G, Li Z, Liu F, Ellsworth K, Dallas-Yang Q, Wu M, Ronan J, Esau C, Murphy C, Szalkowski D, Bergeron R, Doebber T, Zhang BB.

J Clin Invest. 2005 Apr;115(4):1030-8. Epub 2005 Mar 10. Erratum in: J Clin Invest. 2005 Aug;115(8):2297.

PMID:
15761499
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The role of stearoyl-CoA desaturase in body weight regulation.

Dobrzyn A, Ntambi JM.

Trends Cardiovasc Med. 2004 Feb;14(2):77-81. Review.

PMID:
15030794
[PubMed - indexed for MEDLINE]
5.

Recent insights into stearoyl-CoA desaturase-1.

Ntambi JM, Miyazaki M.

Curr Opin Lipidol. 2003 Jun;14(3):255-61. Review.

PMID:
12840656
[PubMed - indexed for MEDLINE]
6.

Loss of stearoyl-CoA desaturase-1 improves insulin sensitivity in lean mice but worsens diabetes in leptin-deficient obese mice.

Flowers JB, Rabaglia ME, Schueler KL, Flowers MT, Lan H, Keller MP, Ntambi JM, Attie AD.

Diabetes. 2007 May;56(5):1228-39. Epub 2007 Mar 16.

PMID:
17369521
[PubMed - indexed for MEDLINE]
Free Article
7.

The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1.

Miyazaki M, Kim YC, Gray-Keller MP, Attie AD, Ntambi JM.

J Biol Chem. 2000 Sep 29;275(39):30132-8.

PMID:
10899171
[PubMed - indexed for MEDLINE]
Free Article
8.
9.

Stearoyl-CoA desaturase--a new player in skeletal muscle metabolism regulation.

Dobrzyń A, Dobrzyń P.

J Physiol Pharmacol. 2006 Nov;57 Suppl 10:31-42. Review.

PMID:
17242489
[PubMed - indexed for MEDLINE]
Free Article
11.

Regulation of stearoyl-CoA desaturase expression.

Ntambi JM, Miyazaki M, Dobrzyn A.

Lipids. 2004 Nov;39(11):1061-5. Review.

PMID:
15726820
[PubMed - indexed for MEDLINE]
12.

Lack of stearoyl-CoA desaturase 1 upregulates basal thermogenesis but causes hypothermia in a cold environment.

Lee SH, Dobrzyn A, Dobrzyn P, Rahman SM, Miyazaki M, Ntambi JM.

J Lipid Res. 2004 Sep;45(9):1674-82. Epub 2004 Jun 21.

PMID:
15210843
[PubMed - indexed for MEDLINE]
Free Article
13.

Loss of stearoyl-CoA desaturase 1 rescues cardiac function in obese leptin-deficient mice.

Dobrzyn P, Dobrzyn A, Miyazaki M, Ntambi JM.

J Lipid Res. 2010 Aug;51(8):2202-10. doi: 10.1194/jlr.M003780. Epub 2010 Apr 2.

PMID:
20363835
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Stearoyl-CoA desaturase 1 deficiency increases insulin signaling and glycogen accumulation in brown adipose tissue.

Rahman SM, Dobrzyn A, Lee SH, Dobrzyn P, Miyazaki M, Ntambi JM.

Am J Physiol Endocrinol Metab. 2005 Feb;288(2):E381-7. Epub 2004 Oct 19.

PMID:
15494611
[PubMed - indexed for MEDLINE]
Free Article
15.

Skin-specific deletion of stearoyl-CoA desaturase-1 alters skin lipid composition and protects mice from high fat diet-induced obesity.

Sampath H, Flowers MT, Liu X, Paton CM, Sullivan R, Chu K, Zhao M, Ntambi JM.

J Biol Chem. 2009 Jul 24;284(30):19961-73. doi: 10.1074/jbc.M109.014225. Epub 2009 May 8.

PMID:
19429677
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Regulation of stearoyl-CoA desaturases and role in metabolism.

Ntambi JM, Miyazaki M.

Prog Lipid Res. 2004 Mar;43(2):91-104. Review.

PMID:
14654089
[PubMed - indexed for MEDLINE]
17.

Stearoyl-CoA desaturase-1 deficiency attenuates obesity and insulin resistance in leptin-resistant obese mice.

Miyazaki M, Sampath H, Liu X, Flowers MT, Chu K, Dobrzyn A, Ntambi JM.

Biochem Biophys Res Commun. 2009 Mar 20;380(4):818-22. doi: 10.1016/j.bbrc.2009.01.183. Epub 2009 Feb 5.

PMID:
19338759
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Loss of stearoyl-CoA desaturase 1 inhibits fatty acid oxidation and increases glucose utilization in the heart.

Dobrzyn P, Sampath H, Dobrzyn A, Miyazaki M, Ntambi JM.

Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E357-64. Epub 2007 Nov 27.

PMID:
18042664
[PubMed - indexed for MEDLINE]
Free Article
19.

Dietary cholesterol opposes PUFA-mediated repression of the stearoyl-CoA desaturase-1 gene by SREBP-1 independent mechanism.

Kim HJ, Miyazaki M, Ntambi JM.

J Lipid Res. 2002 Oct;43(10):1750-7.

PMID:
12364560
[PubMed - indexed for MEDLINE]
Free Article
20.

Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet.

Cedernaes J, Alsiö J, Västermark A, Risérus U, Schiöth HB.

Lipids Health Dis. 2013 Jan 8;12:2. doi: 10.1186/1476-511X-12-2.

PMID:
23298201
[PubMed - indexed for MEDLINE]
Free PMC Article

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