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Items: 1 to 20 of 546

1.

Unique CYP2D6 activity distribution and genotype-phenotype discordance in black Americans.

Gaedigk A, Bradford LD, Marcucci KA, Leeder JS.

Clin Pharmacol Ther. 2002 Jul;72(1):76-89.

PMID:
12152006
2.

The African-specific CYP2D617 allele encodes an enzyme with changed substrate specificity.

Wennerholm A, Dandara C, Sayi J, Svensson JO, Abdi YA, Ingelman-Sundberg M, Bertilsson L, Hasler J, Gustafsson LL.

Clin Pharmacol Ther. 2002 Jan;71(1):77-88.

PMID:
11823760
3.

CYP2D6 polymorphism in a Mexican American population.

Mendoza R, Wan YJ, Poland RE, Smith M, Zheng Y, Berman N, Lin KM.

Clin Pharmacol Ther. 2001 Dec;70(6):552-60.

PMID:
11753272
4.

CYP2D6 phenotype-genotype relationships in African-Americans and Caucasians in Los Angeles.

Leathart JB, London SJ, Steward A, Adams JD, Idle JR, Daly AK.

Pharmacogenetics. 1998 Dec;8(6):529-41.

PMID:
9918137
5.

Low frequency of defective alleles of cytochrome P450 enzymes 2C19 and 2D6 in the Turkish population.

Aynacioglu AS, Sachse C, Bozkurt A, Kortunay S, Nacak M, Schröder T, Kayaalp SO, Roots I, Brockmöller J.

Clin Pharmacol Ther. 1999 Aug;66(2):185-92.

PMID:
10460072
6.

Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences.

Sachse C, Brockmöller J, Bauer S, Roots I.

Am J Hum Genet. 1997 Feb;60(2):284-95.

7.

Analysis of the CYP2D6 gene polymorphism and enzyme activity in African-Americans in southern California.

Wan YJ, Poland RE, Han G, Konishi T, Zheng YP, Berman N, Lin KM.

Pharmacogenetics. 2001 Aug;11(6):489-99.

PMID:
11505219
9.

Comparison of three CYP2D6 probe substrates and genotype in Ghanaians, Chinese and Caucasians.

Droll K, Bruce-Mensah K, Otton SV, Gaedigk A, Sellers EM, Tyndale RF.

Pharmacogenetics. 1998 Aug;8(4):325-33.

PMID:
9731719
10.

CYP2D6 genotype and phenotype relationship in South Indians.

Naveen AT, Prasanna T, Farzana BL, Rajan S, Adithan C.

J Postgrad Med. 2006 Oct-Dec;52(4):253-6.

11.

Assessment of the predictive power of genotypes for the in-vivo catalytic function of CYP2D6 in a German population.

Griese EU, Zanger UM, Brudermanns U, Gaedigk A, Mikus G, Mörike K, Stüven T, Eichelbaum M.

Pharmacogenetics. 1998 Feb;8(1):15-26.

PMID:
9511177
12.

Analysis of the CYP2D6 gene mutations and their consequences for enzyme function in a West African population.

Griese EU, Asante-Poku S, Ofori-Adjei D, Mikus G, Eichelbaum M.

Pharmacogenetics. 1999 Dec;9(6):715-23.

PMID:
10634134
13.

Dose dependency of dextromethorphan for cytochrome P450 2D6 (CYP2D6) phenotyping.

Streetman DS, Ellis RE, Nafziger AN, Leeder JS, Gaedigk A, Gotschall R, Kearns GL, Bertino JS Jr.

Clin Pharmacol Ther. 1999 Nov;66(5):535-41.

PMID:
10579482
14.

CYP2D6*36 gene arrangements within the cyp2d6 locus: association of CYP2D6*36 with poor metabolizer status.

Gaedigk A, Bradford LD, Alander SW, Leeder JS.

Drug Metab Dispos. 2006 Apr;34(4):563-9. Epub 2006 Jan 13.

15.

Decreased capacity for debrisoquine metabolism among black Tanzanians: analyses of the CYP2D6 genotype and phenotype.

Wennerholm A, Johansson I, Massele AY, Lande M, Alm C, Aden-Abdi Y, Dahl ML, Ingelman-Sundberg M, Bertilsson L, Gustafsson LL.

Pharmacogenetics. 1999 Dec;9(6):707-14.

PMID:
10634133
16.

CYP2D6 genotype and phenotype determination in a Mexican Mestizo population.

López M, Guerrero J, Jung-Cook H, Alonso ME.

Eur J Clin Pharmacol. 2005 Nov;61(10):749-54. Epub 2005 Oct 26.

PMID:
16249913
17.

The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype.

Gaedigk A, Simon SD, Pearce RE, Bradford LD, Kennedy MJ, Leeder JS.

Clin Pharmacol Ther. 2008 Feb;83(2):234-42. Epub 2007 Oct 31.

PMID:
17971818
18.

The CYP2D6 gene locus in South African Coloureds: unique allele distributions, novel alleles and gene arrangements.

Gaedigk A, Coetsee C.

Eur J Clin Pharmacol. 2008 May;64(5):465-75. doi: 10.1007/s00228-007-0445-7. Epub 2008 Jan 17.

PMID:
18202841
19.
20.

Determination of cytochrome P450 3A4/5 activity in vivo with dextromethorphan N-demethylation.

Jones DR, Gorski JC, Haehner BD, O'Mara EM Jr, Hall SD.

Clin Pharmacol Ther. 1996 Oct;60(4):374-84.

PMID:
8873685
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