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Items: 1 to 20 of 96

1.

Enhanced mtDNA repair capacity protects pulmonary artery endothelial cells from oxidant-mediated death.

Dobson AW, Grishko V, LeDoux SP, Kelley MR, Wilson GL, Gillespie MN.

Am J Physiol Lung Cell Mol Physiol. 2002 Jul;283(1):L205-10.

2.

Oxygen radical-induced mitochondrial DNA damage and repair in pulmonary vascular endothelial cell phenotypes.

Grishko V, Solomon M, Wilson GL, LeDoux SP, Gillespie MN.

Am J Physiol Lung Cell Mol Physiol. 2001 Jun;280(6):L1300-8.

3.

Mitochondrial DNA damage triggers mitochondrial dysfunction and apoptosis in oxidant-challenged lung endothelial cells.

Ruchko M, Gorodnya O, LeDoux SP, Alexeyev MF, Al-Mehdi AB, Gillespie MN.

Am J Physiol Lung Cell Mol Physiol. 2005 Mar;288(3):L530-5. Epub 2004 Nov 24.

4.

The DNA glycosylase Ogg1 defends against oxidant-induced mtDNA damage and apoptosis in pulmonary artery endothelial cells.

Ruchko MV, Gorodnya OM, Zuleta A, Pastukh VM, Gillespie MN.

Free Radic Biol Med. 2011 May 1;50(9):1107-13. doi: 10.1016/j.freeradbiomed.2010.10.692. Epub 2010 Oct 20.

5.

Targeting human 8-oxoguanine glycosylase to mitochondria of oligodendrocytes protects against menadione-induced oxidative stress.

Druzhyna NM, Hollensworth SB, Kelley MR, Wilson GL, Ledoux SP.

Glia. 2003 Jun;42(4):370-8.

PMID:
12730957
6.
7.

Conditional targeting of the DNA repair enzyme hOGG1 into mitochondria.

Rachek LI, Grishko VI, Musiyenko SI, Kelley MR, LeDoux SP, Wilson GL.

J Biol Chem. 2002 Nov 22;277(47):44932-7. Epub 2002 Sep 19.

8.
9.

Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice.

de Souza-Pinto NC, Eide L, Hogue BA, Thybo T, Stevnsner T, Seeberg E, Klungland A, Bohr VA.

Cancer Res. 2001 Jul 15;61(14):5378-81.

10.

Mitochondrial DNA integrity may be a determinant of endothelial barrier properties in oxidant-challenged rat lungs.

Chouteau JM, Obiako B, Gorodnya OM, Pastukh VM, Ruchko MV, Wright AJ, Wilson GL, Gillespie MN.

Am J Physiol Lung Cell Mol Physiol. 2011 Dec;301(6):L892-8. doi: 10.1152/ajplung.00210.2011. Epub 2011 Sep 2.

11.

Mitochondria-targeted Ogg1 and aconitase-2 prevent oxidant-induced mitochondrial DNA damage in alveolar epithelial cells.

Kim SJ, Cheresh P, Williams D, Cheng Y, Ridge K, Schumacker PT, Weitzman S, Bohr VA, Kamp DW.

J Biol Chem. 2014 Feb 28;289(9):6165-76. doi: 10.1074/jbc.M113.515130. Epub 2014 Jan 15.

13.

Protection of INS-1 cells from free fatty acid-induced apoptosis by targeting hOGG1 to mitochondria.

Rachek LI, Thornley NP, Grishko VI, LeDoux SP, Wilson GL.

Diabetes. 2006 Apr;55(4):1022-8.

14.

Role of nitric oxide-induced mtDNA damage in mitochondrial dysfunction and apoptosis.

Rachek LI, Grishko VI, Ledoux SP, Wilson GL.

Free Radic Biol Med. 2006 Mar 1;40(5):754-62. Epub 2005 Oct 18.

PMID:
16520228
15.

Repair of oxidative damage in mitochondrial DNA of Saccharomyces cerevisiae: involvement of the MSH1-dependent pathway.

Dzierzbicki P, Koprowski P, Fikus MU, Malc E, Ciesla Z.

DNA Repair (Amst). 2004 Apr 1;3(4):403-11.

PMID:
15010316
16.

Homogenous repair of singlet oxygen-induced DNA damage in differentially transcribed regions and strands of human mitochondrial DNA.

Anson RM, Croteau DL, Stierum RH, Filburn C, Parsell R, Bohr VA.

Nucleic Acids Res. 1998 Jan 15;26(2):662-8.

17.

Quantification of oxidative DNA modifications in mitochondria.

Hegler J, Bittner D, Boiteux S, Epe B.

Carcinogenesis. 1993 Nov;14(11):2309-12.

PMID:
8242860
18.

Mitochondrial targeting of human 8-oxoguanine DNA glycosylase hOGG1 is impaired by a somatic mutation found in kidney cancer.

Audebert M, Charbonnier JB, Boiteux S, Radicella JP.

DNA Repair (Amst). 2002 Jul 17;1(7):497-505.

PMID:
12509224
19.

Mitochondrial targeting of human O6-methylguanine DNA methyltransferase protects against cell killing by chemotherapeutic alkylating agents.

Cai S, Xu Y, Cooper RJ, Ferkowicz MJ, Hartwell JR, Pollok KE, Kelley MR.

Cancer Res. 2005 Apr 15;65(8):3319-27.

20.

Increased mitochondrial DNA damage and decreased base excision repair in the auditory cortex of D-galactose-induced aging rats.

Chen B, Zhong Y, Peng W, Sun Y, Hu YJ, Yang Y, Kong WJ.

Mol Biol Rep. 2011 Aug;38(6):3635-42. doi: 10.1007/s11033-010-0476-5. Epub 2010 Nov 21.

PMID:
21104133
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