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Results: 1 to 20 of 400

1.

Phase II trial of carmustine plus O(6)-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma.

Quinn JA, Pluda J, Dolan ME, Delaney S, Kaplan R, Rich JN, Friedman AH, Reardon DA, Sampson JH, Colvin OM, Haglund MM, Pegg AE, Moschel RC, McLendon RE, Provenzale JM, Gururangan S, Tourt-Uhlig S, Herndon JE 2nd, Bigner DD, Friedman HS.

J Clin Oncol. 2002 May 1;20(9):2277-83.

PMID:
11980998
[PubMed - indexed for MEDLINE]
2.

Phase I trial of carmustine plus O6-benzylguanine for patients with recurrent or progressive malignant glioma.

Friedman HS, Pluda J, Quinn JA, Ewesuedo RB, Long L, Friedman AH, Cokgor I, Colvin OM, Haglund MM, Ashley DM, Rich JN, Sampson J, Pegg AE, Moschel RC, McLendon RE, Provenzale JM, Stewart ES, Tourt-Uhlig S, Garcia-Turner AM, Herndon JE 2nd, Bigner DD, Dolan ME.

J Clin Oncol. 2000 Oct 15;18(20):3522-8.

PMID:
11032594
[PubMed - indexed for MEDLINE]
3.

Phase I clinical and pharmacological study of O6-benzylguanine followed by carmustine in patients with advanced cancer.

Schilsky RL, Dolan ME, Bertucci D, Ewesuedo RB, Vogelzang NJ, Mani S, Wilson LR, Ratain MJ.

Clin Cancer Res. 2000 Aug;6(8):3025-31.

PMID:
10955780
[PubMed - indexed for MEDLINE]
Free Article
4.

Phase 1 trial of O6-benzylguanine and BCNU in children with CNS tumors: a Children's Oncology Group study.

Adams DM, Zhou T, Berg SL, Bernstein M, Neville K, Blaney SM; Children's Oncology Group.

Pediatr Blood Cancer. 2008 Mar;50(3):549-53.

PMID:
17941066
[PubMed - indexed for MEDLINE]
5.

Phase I trial of temozolomide plus O6-benzylguanine for patients with recurrent or progressive malignant glioma.

Quinn JA, Desjardins A, Weingart J, Brem H, Dolan ME, Delaney SM, Vredenburgh J, Rich J, Friedman AH, Reardon DA, Sampson JH, Pegg AE, Moschel RC, Birch R, McLendon RE, Provenzale JM, Gururangan S, Dancey JE, Maxwell J, Tourt-Uhlig S, Herndon JE 2nd, Bigner DD, Friedman HS.

J Clin Oncol. 2005 Oct 1;23(28):7178-87.

PMID:
16192602
[PubMed - indexed for MEDLINE]
6.

Phase II trial of the O6-alkylguanine DNA alkyltransferase inhibitor O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea in advanced melanoma.

Gajewski TF, Sosman J, Gerson SL, Liu L, Dolan E, Lin S, Vokes EE.

Clin Cancer Res. 2005 Nov 1;11(21):7861-5.

PMID:
16278409
[PubMed - indexed for MEDLINE]
Free Article
7.

O6-benzylguanine potentiates the antitumor effect of locally delivered carmustine against an intracranial rat glioma.

Rhines LD, Sampath P, Dolan ME, Tyler BM, Brem H, Weingart J.

Cancer Res. 2000 Nov 15;60(22):6307-10.

PMID:
11103789
[PubMed - indexed for MEDLINE]
Free Article
8.

Phase I trial of polifeprosan 20 with carmustine implant plus continuous infusion of intravenous O6-benzylguanine in adults with recurrent malignant glioma: new approaches to brain tumor therapy CNS consortium trial.

Weingart J, Grossman SA, Carson KA, Fisher JD, Delaney SM, Rosenblum ML, Olivi A, Judy K, Tatter SB, Dolan ME.

J Clin Oncol. 2007 Feb 1;25(4):399-404.

PMID:
17264335
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Phase II study of neoadjuvant 1, 3-bis (2-chloroethyl)-1-nitrosourea and temozolomide for newly diagnosed anaplastic glioma: a North American Brain Tumor Consortium Trial.

Chang SM, Prados MD, Yung WK, Fine H, Junck L, Greenberg H, Robins HI, Mehta M, Fink KL, Jaeckle KA, Kuhn J, Hess K, Schold C.

Cancer. 2004 Apr 15;100(8):1712-6.

PMID:
15073861
[PubMed - indexed for MEDLINE]
Free Article
10.

Phase II trial of temozolomide plus o6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma.

Quinn JA, Jiang SX, Reardon DA, Desjardins A, Vredenburgh JJ, Rich JN, Gururangan S, Friedman AH, Bigner DD, Sampson JH, McLendon RE, Herndon JE 2nd, Walker A, Friedman HS.

J Clin Oncol. 2009 Mar 10;27(8):1262-7. doi: 10.1200/JCO.2008.18.8417. Epub 2009 Feb 9.

PMID:
19204199
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.

Raizer JJ, Malkin MG, Kleber M, Abrey LE.

Neuro Oncol. 2004 Jul;6(3):247-52.

PMID:
15279717
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

A phase III study of radiation therapy plus carmustine with or without recombinant interferon-alpha in the treatment of patients with newly diagnosed high-grade glioma.

Buckner JC, Schomberg PJ, McGinnis WL, Cascino TL, Scheithauer BW, O'Fallon JR, Morton RF, Kuross SA, Mailliard JA, Hatfield AK, Cole JT, Steen PD, Bernath AM.

Cancer. 2001 Jul 15;92(2):420-33.

PMID:
11466698
[PubMed - indexed for MEDLINE]
13.

Treatment of subcutaneous and intracranial brain tumor xenografts with O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea.

Felker GM, Friedman HS, Dolan ME, Moschel RC, Schold C.

Cancer Chemother Pharmacol. 1993;32(6):471-6.

PMID:
8258196
[PubMed - indexed for MEDLINE]
14.

Enhancement of nitrosourea activity in medulloblastoma and glioblastoma multiforme.

Friedman HS, Dolan ME, Moschel RC, Pegg AE, Felker GM, Rich J, Bigner DD, Schold SC Jr.

J Natl Cancer Inst. 1992 Dec 16;84(24):1926-31. Erratum in: J Natl Cancer Inst 1994 Jul 6;86(13):1027.

PMID:
1334154
[PubMed - indexed for MEDLINE]
15.

Phase 1 trial of temozolomide plus irinotecan plus O6-benzylguanine in adults with recurrent malignant glioma.

Quinn JA, Jiang SX, Reardon DA, Desjardins A, Vredenburgh JJ, Gururangan S, Sampson JH, McLendon RE, Herndon JE 2nd, Friedman HS.

Cancer. 2009 Jul 1;115(13):2964-70. doi: 10.1002/cncr.24336.

PMID:
19402172
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Phase II study of irinotecan (CPT-11) in children with high-risk malignant brain tumors: the Duke experience.

Turner CD, Gururangan S, Eastwood J, Bottom K, Watral M, Beason R, McLendon RE, Friedman AH, Tourt-Uhlig S, Miller LL, Friedman HS.

Neuro Oncol. 2002 Apr;4(2):102-8.

PMID:
11916501
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

A phase II trial of O6-benzylguanine and carmustine in patients with advanced soft tissue sarcoma.

Ryan CW, Dolan ME, Brockstein BB, McLendon R, Delaney SM, Samuels BL, Agamah ES, Vokes EE.

Cancer Chemother Pharmacol. 2006 Nov;58(5):634-9. Epub 2006 Mar 7.

PMID:
16520986
[PubMed - indexed for MEDLINE]
18.

Second-line chemotherapy with irinotecan plus carmustine in glioblastoma recurrent or progressive after first-line temozolomide chemotherapy: a phase II study of the Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO).

Brandes AA, Tosoni A, Basso U, Reni M, Valduga F, Monfardini S, Amistà P, Nicolardi L, Sotti G, Ermani M.

J Clin Oncol. 2004 Dec 1;22(23):4779-86. Erratum in: J Clin Oncol. 2005 Jan 1;23(1):248.

PMID:
15570079
[PubMed - indexed for MEDLINE]
19.

O6-benzylguanine and BCNU in multiple myeloma: a phase II trial.

Batts ED, Maisel C, Kane D, Liu L, Fu P, O'Brien T, Remick S, Bahlis N, Gerson SL.

Cancer Chemother Pharmacol. 2007 Aug;60(3):415-21. Epub 2007 Mar 13.

PMID:
17354015
[PubMed - indexed for MEDLINE]
20.

Phase I trial of O6-benzylguanine for patients undergoing surgery for malignant glioma.

Friedman HS, Kokkinakis DM, Pluda J, Friedman AH, Cokgor I, Haglund MM, Ashley DM, Rich J, Dolan ME, Pegg AE, Moschel RC, McLendon RE, Kerby T, Herndon JE, Bigner DD, Schold SC Jr.

J Clin Oncol. 1998 Nov;16(11):3570-5.

PMID:
9817277
[PubMed - indexed for MEDLINE]

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