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Results: 1 to 20 of 120

1.

Molecular and pharmacological characterization of genes encoding urotensin-II peptides and their cognate G-protein-coupled receptors from the mouse and monkey.

Elshourbagy NA, Douglas SA, Shabon U, Harrison S, Duddy G, Sechler JL, Ao Z, Maleeff BE, Naselsky D, Disa J, Aiyar NV.

Br J Pharmacol. 2002 May;136(1):9-22.

PMID:
11976263
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Identification and pharmacological characterization of native, functional human urotensin-II receptors in rhabdomyosarcoma cell lines.

Douglas SA, Naselsky D, Ao Z, Disa J, Herold CL, Lynch F, Aiyar NV.

Br J Pharmacol. 2004 Jul;142(6):921-32. Epub 2004 Jun 21.

PMID:
15210573
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Cloning and pharmacological characterization of the cat urotensin-II receptor (UT).

Aiyar N, Johns DG, Ao Z, Disa J, Behm DJ, Foley JJ, Buckley PT, Sarau HM, van-der-Keyl HK, Elshourbagy NA, Douglas SA.

Biochem Pharmacol. 2005 Apr 1;69(7):1069-79.

PMID:
15763543
[PubMed - indexed for MEDLINE]
4.

Palosuran inhibits binding to primate UT receptors in cell membranes but demonstrates differential activity in intact cells and vascular tissues.

Behm DJ, McAtee JJ, Dodson JW, Neeb MJ, Fries HE, Evans CA, Hernandez RR, Hoffman KD, Harrison SM, Lai JM, Wu C, Aiyar NV, Ohlstein EH, Douglas SA.

Br J Pharmacol. 2008 Oct;155(3):374-86. doi: 10.1038/bjp.2008.266. Epub 2008 Jun 30.

PMID:
18587423
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Nonpeptidic urotensin-II receptor antagonists I: in vitro pharmacological characterization of SB-706375.

Douglas SA, Behm DJ, Aiyar NV, Naselsky D, Disa J, Brooks DP, Ohlstein EH, Gleason JG, Sarau HM, Foley JJ, Buckley PT, Schmidt DB, Wixted WE, Widdowson K, Riley G, Jin J, Gallagher TF, Schmidt SJ, Ridgers L, Christmann LT, Keenan RM, Knight SD, Dhanak D.

Br J Pharmacol. 2005 Jul;145(5):620-35.

PMID:
15852036
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

GSK1562590, a slowly dissociating urotensin-II receptor antagonist, exhibits prolonged pharmacodynamic activity ex vivo.

Behm DJ, Aiyar NV, Olzinski AR, McAtee JJ, Hilfiker MA, Dodson JW, Dowdell SE, Wang GZ, Goodman KB, Sehon CA, Harpel MR, Willette RN, Neeb MJ, Leach CA, Douglas SA.

Br J Pharmacol. 2010 Sep;161(1):207-28. doi: 10.1111/j.1476-5381.2010.00889.x.

PMID:
20718751
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Urotensin II is a new chemotactic factor for UT receptor-expressing monocytes.

Segain JP, Rolli-Derkinderen M, Gervois N, Raingeard de la Blétière D, Loirand G, Pacaud P.

J Immunol. 2007 Jul 15;179(2):901-9.

PMID:
17617581
[PubMed - indexed for MEDLINE]
Free Article
8.

Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14.

Ames RS, Sarau HM, Chambers JK, Willette RN, Aiyar NV, Romanic AM, Louden CS, Foley JJ, Sauermelch CF, Coatney RW, Ao Z, Disa J, Holmes SD, Stadel JM, Martin JD, Liu WS, Glover GI, Wilson S, McNulty DE, Ellis CE, Elshourbagy NA, Shabon U, Trill JJ, Hay DW, Ohlstein EH, Bergsma DJ, Douglas SA.

Nature. 1999 Sep 16;401(6750):282-6. Erratum in: Nature 1999 Dec 23-30;402(6764):898.

PMID:
10499587
[PubMed - indexed for MEDLINE]
9.

The peptidic urotensin-II receptor ligand GSK248451 possesses less intrinsic activity than the low-efficacy partial agonists SB-710411 and urantide in native mammalian tissues and recombinant cell systems.

Behm DJ, Stankus G, Doe CP, Willette RN, Sarau HM, Foley JJ, Schmidt DB, Nuthulaganti P, Fornwald JA, Ames RS, Lambert DG, Calo' G, Camarda V, Aiyar NV, Douglas SA.

Br J Pharmacol. 2006 May;148(2):173-90.

PMID:
16547525
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Elevated expression of urotensin II and its receptor in skeletal muscle of diabetic mouse.

Wang HX, Zeng XJ, Liu Y, Wang J, Lu LQ, Hao G, Zhang LK, Tang CS.

Regul Pept. 2009 Apr 10;154(1-3):85-90. doi: 10.1016/j.regpep.2009.01.004. Epub 2009 Jan 27.

PMID:
19323985
[PubMed - indexed for MEDLINE]
11.

Characterization of functional urotensin II receptors in human skeletal muscle myoblasts: comparison with angiotensin II receptors.

Qi JS, Minor LK, Smith C, Hu B, Yang J, Andrade-Gordon P, Damiano B.

Peptides. 2005 Apr;26(4):683-90. Epub 2005 Jan 1.

PMID:
15752584
[PubMed - indexed for MEDLINE]
12.

Biochemical and pharmacological characterization of nuclear urotensin-II binding sites in rat heart.

Doan ND, Nguyen TT, Létourneau M, Turcotte K, Fournier A, Chatenet D.

Br J Pharmacol. 2012 May;166(1):243-57. doi: 10.1111/j.1476-5381.2011.01710.x.

PMID:
22044114
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Urotensin II: a novel target in human corpus cavernosum.

d'Emmanuele di Villa Bianca R, Cirino G, Mitidieri E, Coletta C, Grassia G, Roviezzo F, Grieco P, Novellino E, Imbimbo C, Mirone V, Sorrentino R.

J Sex Med. 2010 May;7(5):1778-86. doi: 10.1111/j.1743-6109.2009.01450.x. Epub 2009 Sep 25.

PMID:
19788716
[PubMed - indexed for MEDLINE]
14.

Congestive heart failure and expression of myocardial urotensin II.

Douglas SA, Tayara L, Ohlstein EH, Halawa N, Giaid A.

Lancet. 2002 Jun 8;359(9322):1990-7.

PMID:
12076554
[PubMed - indexed for MEDLINE]
15.

Identification and characterization of binding sites for human urotensin-II in Sprague-Dawley rat renal medulla using quantitative receptor autoradiography.

Disa J, Floyd LE, Edwards RM, Douglas SA, Aiyar NV.

Peptides. 2006 Jun;27(6):1532-7. Epub 2005 Nov 14.

PMID:
16290260
[PubMed - indexed for MEDLINE]
16.

Photolabelling the urotensin II receptor reveals distinct agonist- and partial-agonist-binding sites.

Holleran BJ, Beaulieu ME, Proulx CD, Lavigne P, Escher E, Leduc R.

Biochem J. 2007 Feb 15;402(1):51-61.

PMID:
17064254
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Differential agonistic and antagonistic effects of the urotensin-II ligand SB-710411 at rodent and primate UT receptors.

Behm DJ, Herold CL, Camarda V, Aiyar NV, Douglas SA.

Eur J Pharmacol. 2004 May 25;492(2-3):113-6.

PMID:
15178353
[PubMed - indexed for MEDLINE]
18.

Photolabelling the rat urotensin II/GPR14 receptor identifies a ligand-binding site in the fourth transmembrane domain.

Boucard AA, Sauvé SS, Guillemette G, Escher E, Leduc R.

Biochem J. 2003 Mar 15;370(Pt 3):829-38.

PMID:
12495432
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Urotensin II is the endogenous ligand of a G-protein-coupled orphan receptor, SENR (GPR14).

Mori M, Sugo T, Abe M, Shimomura Y, Kurihara M, Kitada C, Kikuchi K, Shintani Y, Kurokawa T, Onda H, Nishimura O, Fujino M.

Biochem Biophys Res Commun. 1999 Nov;265(1):123-9.

PMID:
10548501
[PubMed - indexed for MEDLINE]
20.

Desensitisation of native and recombinant human urotensin-II receptors.

Batuwangala MS, Calo G, Guerrini R, Ng LL, McDonald J, Lambert DG.

Naunyn Schmiedebergs Arch Pharmacol. 2009 Nov;380(5):451-7. doi: 10.1007/s00210-009-0441-9. Epub 2009 Aug 13.

PMID:
19680632
[PubMed - indexed for MEDLINE]

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