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Items: 1 to 20 of 90

2.

DNA-PKcs dependence of Artemis endonucleolytic activity, differences between hairpins and 5' or 3' overhangs.

Niewolik D, Pannicke U, Lu H, Ma Y, Wang LC, Kulesza P, Zandi E, Lieber MR, Schwarz K.

J Biol Chem. 2006 Nov 10;281(45):33900-9. Epub 2006 Aug 16.

3.

Functional and biochemical dissection of the structure-specific nuclease ARTEMIS.

Pannicke U, Ma Y, Hopfner KP, Niewolik D, Lieber MR, Schwarz K.

EMBO J. 2004 May 5;23(9):1987-97. Epub 2004 Apr 8.

4.

Artemis-independent functions of DNA-dependent protein kinase in Ig heavy chain class switch recombination and development.

Rooney S, Alt FW, Sekiguchi J, Manis JP.

Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2471-5. Epub 2005 Feb 7.

5.

The Artemis:DNA-PKcs endonuclease cleaves DNA loops, flaps, and gaps.

Ma Y, Schwarz K, Lieber MR.

DNA Repair (Amst). 2005 Jul 12;4(7):845-51.

PMID:
15936993
6.

Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice.

Rooney S, Sekiguchi J, Zhu C, Cheng HL, Manis J, Whitlow S, DeVido J, Foy D, Chaudhuri J, Lombard D, Alt FW.

Mol Cell. 2002 Dec;10(6):1379-90.

7.
8.
9.

Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination.

Lee BS, Gapud EJ, Zhang S, Dorsett Y, Bredemeyer A, George R, Callen E, Daniel JA, Osipovich O, Oltz EM, Bassing CH, Nussenzweig A, Lees-Miller S, Hammel M, Chen BP, Sleckman BP.

Mol Cell Biol. 2013 Sep;33(18):3568-79. doi: 10.1128/MCB.00308-13. Epub 2013 Jul 8.

10.

The DNA-dependent protein kinase catalytic subunit phosphorylation sites in human Artemis.

Ma Y, Pannicke U, Lu H, Niewolik D, Schwarz K, Lieber MR.

J Biol Chem. 2005 Oct 7;280(40):33839-46. Epub 2005 Aug 10.

11.

DNA-PK autophosphorylation facilitates Artemis endonuclease activity.

Goodarzi AA, Yu Y, Riballo E, Douglas P, Walker SA, Ye R, Härer C, Marchetti C, Morrice N, Jeggo PA, Lees-Miller SP.

EMBO J. 2006 Aug 23;25(16):3880-9. Epub 2006 Jul 27.

12.

Unifying the DNA end-processing roles of the artemis nuclease: Ku-dependent artemis resection at blunt DNA ends.

Chang HH, Watanabe G, Lieber MR.

J Biol Chem. 2015 Oct 2;290(40):24036-50. doi: 10.1074/jbc.M115.680900. Epub 2015 Aug 14.

PMID:
26276388
13.

Defective DNA repair and increased genomic instability in Artemis-deficient murine cells.

Rooney S, Alt FW, Lombard D, Whitlow S, Eckersdorff M, Fleming J, Fugmann S, Ferguson DO, Schatz DG, Sekiguchi J.

J Exp Med. 2003 Mar 3;197(5):553-65.

14.

Interplay between Ku, Artemis, and the DNA-dependent protein kinase catalytic subunit at DNA ends.

Drouet J, Frit P, Delteil C, de Villartay JP, Salles B, Calsou P.

J Biol Chem. 2006 Sep 22;281(38):27784-93. Epub 2006 Jul 19.

15.

The DNA-dependent protein kinase interacts with DNA to form a protein-DNA complex that is disrupted by phosphorylation.

Merkle D, Douglas P, Moorhead GB, Leonenko Z, Yu Y, Cramb D, Bazett-Jones DP, Lees-Miller SP.

Biochemistry. 2002 Oct 22;41(42):12706-14.

PMID:
12379113
16.

A DNA-PKcs mutation in a radiosensitive T-B- SCID patient inhibits Artemis activation and nonhomologous end-joining.

van der Burg M, Ijspeert H, Verkaik NS, Turul T, Wiegant WW, Morotomi-Yano K, Mari PO, Tezcan I, Chen DJ, Zdzienicka MZ, van Dongen JJ, van Gent DC.

J Clin Invest. 2009 Jan;119(1):91-8. doi: 10.1172/JCI37141. Epub 2008 Dec 15.

17.

DNA-PKcs and Artemis function in the end-joining phase of immunoglobulin heavy chain class switch recombination.

Franco S, Murphy MM, Li G, Borjeson T, Boboila C, Alt FW.

J Exp Med. 2008 Mar 17;205(3):557-64. doi: 10.1084/jem.20080044. Epub 2008 Mar 3.

18.

Distinct effects of DNA-PKcs and Artemis inactivation on signal joint formation in vivo.

Touvrey C, Couedel C, Soulas P, Couderc R, Jasin M, de Villartay JP, Marche PN, Jouvin-Marche E, Candéias SM.

Mol Immunol. 2008 Jul;45(12):3383-91. doi: 10.1016/j.molimm.2008.04.004. Epub 2008 May 23.

PMID:
18501428
19.

DNA-PKcs deficiency in human: long predicted, finally found.

van der Burg M, van Dongen JJ, van Gent DC.

Curr Opin Allergy Clin Immunol. 2009 Dec;9(6):503-9. doi: 10.1097/ACI.0b013e3283327e41. Review.

PMID:
19823081
20.

V(D)J recombination catalyzed by mutant RAG proteins lacking consensus DNA-PK phosphorylation sites.

Lin JM, Landree MA, Roth DB.

Mol Immunol. 1999 Dec;36(18):1263-9.

PMID:
10684966
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