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Results: 1 to 20 of 163

1.

ClpS, a substrate modulator of the ClpAP machine.

Dougan DA, Reid BG, Horwich AL, Bukau B.

Mol Cell. 2002 Mar;9(3):673-83.

PMID:
11931773
[PubMed - indexed for MEDLINE]
Free Article
2.

An intrinsic degradation tag on the ClpA C-terminus regulates the balance of ClpAP complexes with different substrate specificity.

Maglica Z, Striebel F, Weber-Ban E.

J Mol Biol. 2008 Dec 12;384(2):503-11. doi: 10.1016/j.jmb.2008.09.046. Epub 2008 Sep 26.

PMID:
18835567
[PubMed - indexed for MEDLINE]
3.

Structural analysis of the adaptor protein ClpS in complex with the N-terminal domain of ClpA.

Zeth K, Ravelli RB, Paal K, Cusack S, Bukau B, Dougan DA.

Nat Struct Biol. 2002 Dec;9(12):906-11.

PMID:
12426582
[PubMed - indexed for MEDLINE]
4.

ClpS is an essential component of the N-end rule pathway in Escherichia coli.

Erbse A, Schmidt R, Bornemann T, Schneider-Mergener J, Mogk A, Zahn R, Dougan DA, Bukau B.

Nature. 2006 Feb 9;439(7077):753-6.

PMID:
16467841
[PubMed - indexed for MEDLINE]
5.

Crystal structure of the heterodimeric complex of the adaptor, ClpS, with the N-domain of the AAA+ chaperone, ClpA.

Guo F, Esser L, Singh SK, Maurizi MR, Xia D.

J Biol Chem. 2002 Nov 29;277(48):46753-62. Epub 2002 Sep 15.

PMID:
12235156
[PubMed - indexed for MEDLINE]
Free Article
6.

Conserved residues in the N-domain of the AAA+ chaperone ClpA regulate substrate recognition and unfolding.

Erbse AH, Wagner JN, Truscott KN, Spall SK, Kirstein J, Zeth K, Turgay K, Mogk A, Bukau B, Dougan DA.

FEBS J. 2008 Apr;275(7):1400-10. doi: 10.1111/j.1742-4658.2008.06304.x. Epub 2008 Feb 14.

PMID:
18279386
[PubMed - indexed for MEDLINE]
7.

Substrate recognition by the ClpA chaperone component of ClpAP protease.

Hoskins JR, Kim SY, Wickner S.

J Biol Chem. 2000 Nov 10;275(45):35361-7.

PMID:
10952988
[PubMed - indexed for MEDLINE]
Free Article
8.

Distinct structural elements of the adaptor ClpS are required for regulating degradation by ClpAP.

Hou JY, Sauer RT, Baker TA.

Nat Struct Mol Biol. 2008 Mar;15(3):288-94. doi: 10.1038/nsmb.1392. Epub 2008 Feb 24.

PMID:
18297088
[PubMed - indexed for MEDLINE]
9.

Cytoplasmic degradation of ssrA-tagged proteins.

Farrell CM, Grossman AD, Sauer RT.

Mol Microbiol. 2005 Sep;57(6):1750-61.

PMID:
16135238
[PubMed - indexed for MEDLINE]
10.

The flexible attachment of the N-domains to the ClpA ring body allows their use on demand.

Cranz-Mileva S, Imkamp F, Kolygo K, Maglica Z, Kress W, Weber-Ban E.

J Mol Biol. 2008 Apr 25;378(2):412-24. doi: 10.1016/j.jmb.2008.02.047. Epub 2008 Feb 29.

PMID:
18358489
[PubMed - indexed for MEDLINE]
11.

Protein binding and unfolding by the chaperone ClpA and degradation by the protease ClpAP.

Hoskins JR, Singh SK, Maurizi MR, Wickner S.

Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):8892-7.

PMID:
10922051
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

ClpA and ClpP remain associated during multiple rounds of ATP-dependent protein degradation by ClpAP protease.

Singh SK, Guo F, Maurizi MR.

Biochemistry. 1999 Nov 9;38(45):14906-15.

PMID:
10555973
[PubMed - indexed for MEDLINE]
13.

ClpS is the recognition component for Escherichia coli substrates of the N-end rule degradation pathway.

Schmidt R, Zahn R, Bukau B, Mogk A.

Mol Microbiol. 2009 Apr;72(2):506-17. doi: 10.1111/j.1365-2958.2009.06666.x. Epub 2009 Mar 17.

PMID:
19317833
[PubMed - indexed for MEDLINE]
14.

The molecular chaperone, ClpA, has a single high affinity peptide binding site per hexamer.

Piszczek G, Rozycki J, Singh SK, Ginsburg A, Maurizi MR.

J Biol Chem. 2005 Apr 1;280(13):12221-30. Epub 2005 Jan 18.

PMID:
15657062
[PubMed - indexed for MEDLINE]
Free Article
15.

Binding and degradation of heterodimeric substrates by ClpAP and ClpXP.

Sharma S, Hoskins JR, Wickner S.

J Biol Chem. 2005 Feb 18;280(7):5449-55. Epub 2004 Dec 8.

PMID:
15591068
[PubMed - indexed for MEDLINE]
Free Article
16.

The ClpXP and ClpAP proteases degrade proteins with carboxy-terminal peptide tails added by the SsrA-tagging system.

Gottesman S, Roche E, Zhou Y, Sauer RT.

Genes Dev. 1998 May 1;12(9):1338-47.

PMID:
9573050
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Functional domains of the ClpA and ClpX molecular chaperones identified by limited proteolysis and deletion analysis.

Singh SK, Rozycki J, Ortega J, Ishikawa T, Lo J, Steven AC, Maurizi MR.

J Biol Chem. 2001 Aug 3;276(31):29420-9. Epub 2001 May 9.

PMID:
11346657
[PubMed - indexed for MEDLINE]
Free Article
18.

ClpA mediates directional translocation of substrate proteins into the ClpP protease.

Reid BG, Fenton WA, Horwich AL, Weber-Ban EU.

Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3768-72. Epub 2001 Mar 20.

PMID:
11259663
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Concurrent chaperone and protease activities of ClpAP and the requirement for the N-terminal ClpA ATP binding site for chaperone activity.

Pak M, Hoskins JR, Singh SK, Maurizi MR, Wickner S.

J Biol Chem. 1999 Jul 2;274(27):19316-22.

PMID:
10383442
[PubMed - indexed for MEDLINE]
Free Article
20.

Overlapping recognition determinants within the ssrA degradation tag allow modulation of proteolysis.

Flynn JM, Levchenko I, Seidel M, Wickner SH, Sauer RT, Baker TA.

Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10584-9. Epub 2001 Sep 4.

PMID:
11535833
[PubMed - indexed for MEDLINE]
Free PMC Article

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