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Items: 1 to 20 of 83

1.

Opioid tolerance-in search of the holy grail.

Kieffer BL, Evans CJ.

Cell. 2002 Mar 8;108(5):587-90. Review.

3.

Protein kinases modulate the cellular adaptations associated with opioid tolerance and dependence.

Liu JG, Anand KJ.

Brain Res Brain Res Rev. 2001 Dec;38(1-2):1-19. Review.

PMID:
11750924
4.

Role of receptor internalization in opioid tolerance and dependence.

Koch T, Höllt V.

Pharmacol Ther. 2008 Feb;117(2):199-206. Epub 2007 Nov 17. Review.

PMID:
18076994
5.
6.

Opioid tolerance and the emergence of new opioid receptor-coupled signaling.

Gintzler AR, Chakrabarti S.

Mol Neurobiol. 2000 Feb-Apr;21(1-2):21-33. Review.

PMID:
11327148
7.

Regulation of opioid receptor trafficking and morphine tolerance by receptor oligomerization.

He L, Fong J, von Zastrow M, Whistler JL.

Cell. 2002 Jan 25;108(2):271-82.

8.

The role of mu opioid receptor desensitization and endocytosis in morphine tolerance and dependence.

Martini L, Whistler JL.

Curr Opin Neurobiol. 2007 Oct;17(5):556-64. Epub 2007 Dec 18. Review.

PMID:
18068348
9.

Opiate tolerance and dependence: receptors, G-proteins, and antiopiates.

Harrison LM, Kastin AJ, Zadina JE.

Peptides. 1998;19(9):1603-30. Review.

PMID:
9864069
10.

The human mu opioid receptor: modulation of functional desensitization by calcium/calmodulin-dependent protein kinase and protein kinase C.

Mestek A, Hurley JH, Bye LS, Campbell AD, Chen Y, Tian M, Liu J, Schulman H, Yu L.

J Neurosci. 1995 Mar;15(3 Pt 2):2396-406.

11.

Receptor endocytosis counteracts the development of opioid tolerance.

Koch T, Widera A, Bartzsch K, Schulz S, Brandenburg LO, Wundrack N, Beyer A, Grecksch G, Höllt V.

Mol Pharmacol. 2005 Jan;67(1):280-7. Epub 2004 Oct 8.

12.

Receptor mechanisms of opioid tolerance in SH-SY5Y human neural cells.

Carter BD, Medzihradsky F.

Mol Pharmacol. 1993 Mar;43(3):465-73.

PMID:
8383804
13.
14.

Morphine-activated opioid receptors elude desensitization by beta-arrestin.

Whistler JL, von Zastrow M.

Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):9914-9.

15.

Effect of agmatine on DAMGO-induced mu-opioid receptor down-regulation and internalization via activation of IRAS, a candidate for imidazoline I(1) receptor.

Gao Y, Li F, Wu N, Su RB, Liu Y, Lu XQ, Liu Y, Li J.

Eur J Pharmacol. 2008 Dec 3;599(1-3):18-23. doi: 10.1016/j.ejphar.2008.09.020. Epub 2008 Sep 26.

PMID:
18845140
16.
17.

Post-opioid receptor adaptations to chronic morphine; altered functionality and associations of signaling molecules.

Gintzler AR, Chakrabarti S.

Life Sci. 2006 Jul 17;79(8):717-22. Epub 2006 Mar 6. Review.

PMID:
16581089
19.

The role of opioid receptor internalization and beta-arrestins in the development of opioid tolerance.

Zuo Z.

Anesth Analg. 2005 Sep;101(3):728-34, table of contents. Review.

PMID:
16115983
20.

Agonist-regulated internalization and desensitization of the human nociceptin receptor expressed in CHO cells.

Spampinato S, Baiula M, Calienni M.

Curr Drug Targets. 2007 Jan;8(1):137-46. Review.

PMID:
17266537
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