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Honokiol inhibits TNF-alpha-stimulated NF-kappaB activation and NF-kappaB-regulated gene expression through suppression of IKK activation.

Tse AK, Wan CK, Shen XL, Yang M, Fong WF.

Biochem Pharmacol. 2005 Nov 15;70(10):1443-57. Epub 2005 Sep 21.


Heme oxygenase-1-derived carbon monoxide requires the activation of transcription factor NF-kappa B to protect endothelial cells from tumor necrosis factor-alpha-mediated apoptosis.

Brouard S, Berberat PO, Tobiasch E, Seldon MP, Bach FH, Soares MP.

J Biol Chem. 2002 May 17;277(20):17950-61. Epub 2002 Mar 5.


Inhibition of NF-kappa B activation through targeting I kappa B kinase by celastrol, a quinone methide triterpenoid.

Lee JH, Koo TH, Yoon H, Jung HS, Jin HZ, Lee K, Hong YS, Lee JJ.

Biochem Pharmacol. 2006 Nov 15;72(10):1311-21. Epub 2006 Sep 18.


Suppression of RelA/p65 transactivation activity by a lignoid manassantin isolated from Saururus chinensis.

Lee JH, Hwang BY, Kim KS, Nam JB, Hong YS, Lee JJ.

Biochem Pharmacol. 2003 Nov 15;66(10):1925-33.


Targeting nuclear factor-kappa B activation pathway by thymoquinone: role in suppression of antiapoptotic gene products and enhancement of apoptosis.

Sethi G, Ahn KS, Aggarwal BB.

Mol Cancer Res. 2008 Jun;6(6):1059-70. doi: 10.1158/1541-7786.MCR-07-2088.


Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-kappa B pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis.

Kunnumakkara AB, Ichikawa H, Anand P, Mohankumar CJ, Hema PS, Nair MS, Aggarwal BB.

Mol Cancer Ther. 2008 Oct;7(10):3306-17. doi: 10.1158/1535-7163.MCT-08-0432.


15-Deoxy-Delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit.

Cernuda-Morollón E, Pineda-Molina E, Cañada FJ, Pérez-Sala D.

J Biol Chem. 2001 Sep 21;276(38):35530-6. Epub 2001 Jul 20.


Magnolol suppresses NF-kappaB activation and NF-kappaB regulated gene expression through inhibition of IkappaB kinase activation.

Tse AK, Wan CK, Zhu GY, Shen XL, Cheung HY, Yang M, Fong WF.

Mol Immunol. 2007 Apr;44(10):2647-58. Epub 2007 Jan 22.


17-Acetoxyjolkinolide B irreversibly inhibits IkappaB kinase and induces apoptosis of tumor cells.

Yan SS, Li Y, Wang Y, Shen SS, Gu Y, Wang HB, Qin GW, Yu Q.

Mol Cancer Ther. 2008 Jun;7(6):1523-32. doi: 10.1158/1535-7163.MCT-08-0263.


Inhibition of transcription factor NF-kappaB signaling proteins IKKbeta and p65 through specific cysteine residues by epoxyquinone A monomer: correlation with its anti-cancer cell growth activity.

Liang MC, Bardhan S, Pace EA, Rosman D, Beutler JA, Porco JA Jr, Gilmore TD.

Biochem Pharmacol. 2006 Feb 28;71(5):634-45. Epub 2005 Dec 19.


Novel mechanism of inhibition of nuclear factor-kappa B DNA-binding activity by diterpenoids isolated from Isodon rubescens.

Leung CH, Grill SP, Lam W, Han QB, Sun HD, Cheng YC.

Mol Pharmacol. 2005 Aug;68(2):286-97. Epub 2005 May 4.


Blockade of nuclear factor-kappaB signaling pathway and anti-inflammatory activity of cardamomin, a chalcone analog from Alpinia conchigera.

Lee JH, Jung HS, Giang PM, Jin X, Lee S, Son PT, Lee D, Hong YS, Lee K, Lee JJ.

J Pharmacol Exp Ther. 2006 Jan;316(1):271-8. Epub 2005 Sep 23.

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