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Results: 1 to 20 of 101

1.

Haptoglobin and CD163: captor and receptor gating hemoglobin to macrophage lysosomes.

Madsen M, Graversen JH, Moestrup SK.

Redox Rep. 2001;6(6):386-8. Review.

PMID:
11865982
[PubMed - indexed for MEDLINE]
2.

Identification of the haemoglobin scavenger receptor.

Kristiansen M, Graversen JH, Jacobsen C, Sonne O, Hoffman HJ, Law SK, Moestrup SK.

Nature. 2001 Jan 11;409(6817):198-201.

PMID:
11196644
[PubMed - indexed for MEDLINE]
3.

CD163: a signal receptor scavenging haptoglobin-hemoglobin complexes from plasma.

Graversen JH, Madsen M, Moestrup SK.

Int J Biochem Cell Biol. 2002 Apr;34(4):309-14. Review.

PMID:
11854028
[PubMed - indexed for MEDLINE]
4.

Soluble macrophage-derived CD163: a homogenous ectodomain protein with a dissociable haptoglobin-hemoglobin binding.

Møller HJ, Nielsen MJ, Maniecki MB, Madsen M, Moestrup SK.

Immunobiology. 2010 May;215(5):406-12. doi: 10.1016/j.imbio.2009.05.003. Epub 2009 Jul 5.

PMID:
19581020
[PubMed - indexed for MEDLINE]
5.

CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin.

Schaer DJ, Schaer CA, Buehler PW, Boykins RA, Schoedon G, Alayash AI, Schaffner A.

Blood. 2006 Jan 1;107(1):373-80. Epub 2005 Sep 27.

PMID:
16189277
[PubMed - indexed for MEDLINE]
Free Article
6.

Molecular characterization of the haptoglobin.hemoglobin receptor CD163. Ligand binding properties of the scavenger receptor cysteine-rich domain region.

Madsen M, Møller HJ, Nielsen MJ, Jacobsen C, Graversen JH, van den Berg T, Moestrup SK.

J Biol Chem. 2004 Dec 3;279(49):51561-7. Epub 2004 Sep 24.

PMID:
15448162
[PubMed - indexed for MEDLINE]
Free Article
7.

Plasma clearance of hemoglobin and haptoglobin in mice and effect of CD163 gene targeting disruption.

Etzerodt A, Kjolby M, Nielsen MJ, Maniecki M, Svendsen P, Moestrup SK.

Antioxid Redox Signal. 2013 Jun 10;18(17):2254-63. doi: 10.1089/ars.2012.4605. Epub 2012 Aug 29.

PMID:
22793784
[PubMed - indexed for MEDLINE]
8.

CD163-expressing monocytes constitute an endotoxin-sensitive Hb clearance compartment within the vascular system.

Schaer CA, Vallelian F, Imhof A, Schoedon G, Schaer DJ.

J Leukoc Biol. 2007 Jul;82(1):106-10. Epub 2007 Apr 25.

PMID:
17460152
[PubMed - indexed for MEDLINE]
Free Article
9.

A unique loop extension in the serine protease domain of haptoglobin is essential for CD163 recognition of the haptoglobin-hemoglobin complex.

Nielsen MJ, Petersen SV, Jacobsen C, Thirup S, Enghild JJ, Graversen JH, Moestrup SK.

J Biol Chem. 2007 Jan 12;282(2):1072-9. Epub 2006 Nov 13.

PMID:
17102136
[PubMed - indexed for MEDLINE]
Free Article
10.

Identification of the hemoglobin scavenger receptor/CD163 as a natural soluble protein in plasma.

Møller HJ, Peterslund NA, Graversen JH, Moestrup SK.

Blood. 2002 Jan 1;99(1):378-80.

PMID:
11756196
[PubMed - indexed for MEDLINE]
Free Article
11.

Gating the radical hemoglobin to macrophages: the anti-inflammatory role of CD163, a scavenger receptor.

Schaer DJ, Alayash AI, Buehler PW.

Antioxid Redox Signal. 2007 Jul;9(7):991-9. Review.

PMID:
17508920
[PubMed - indexed for MEDLINE]
12.
13.

The intrathecal CD163-haptoglobin-hemoglobin scavenging system in subarachnoid hemorrhage.

Galea J, Cruickshank G, Teeling JL, Boche D, Garland P, Perry VH, Galea I.

J Neurochem. 2012 Jun;121(5):785-92. doi: 10.1111/j.1471-4159.2012.07716.x. Epub 2012 Mar 30.

PMID:
22380637
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

CD163: a regulated hemoglobin scavenger receptor with a role in the anti-inflammatory response.

Moestrup SK, Møller HJ.

Ann Med. 2004;36(5):347-54. Review.

PMID:
15478309
[PubMed - indexed for MEDLINE]
15.

Receptor targeting of hemoglobin mediated by the haptoglobins: roles beyond heme scavenging.

Nielsen MJ, Moestrup SK.

Blood. 2009 Jul 23;114(4):764-71. doi: 10.1182/blood-2009-01-198309. Epub 2009 Apr 20. Review.

PMID:
19380867
[PubMed - indexed for MEDLINE]
Free Article
16.

CD163-L1 is an endocytic macrophage protein strongly regulated by mediators in the inflammatory response.

Moeller JB, Nielsen MJ, Reichhardt MP, Schlosser A, Sorensen GL, Nielsen O, Tornøe I, Grønlund J, Nielsen ME, Jørgensen JS, Jensen ON, Mollenhauer J, Moestrup SK, Holmskov U.

J Immunol. 2012 Mar 1;188(5):2399-409. doi: 10.4049/jimmunol.1103150. Epub 2012 Jan 25.

PMID:
22279103
[PubMed - indexed for MEDLINE]
Free Article
17.

Heme carrier protein (HCP-1) spatially interacts with the CD163 hemoglobin uptake pathway and is a target of inflammatory macrophage activation.

Schaer CA, Vallelian F, Imhof A, Schoedon G, Schaer DJ.

J Leukoc Biol. 2008 Feb;83(2):325-33. Epub 2007 Oct 18.

PMID:
17947394
[PubMed - indexed for MEDLINE]
Free Article
18.

Regulation of surface CD163 expression and cellular effects of receptor mediated hemoglobin-haptoglobin uptake on human monocytes and macrophages.

Ugocsai P, Barlage S, Dada A, Schmitz G.

Cytometry A. 2006 Mar;69(3):203-5.

PMID:
16479607
[PubMed - indexed for MEDLINE]
Free Article
19.

Comparative assessment of the recognition of domain-specific CD163 monoclonal antibodies in human monocytes explains wide discrepancy in reported levels of cellular surface CD163 expression.

Maniecki MB, Etzerodt A, Moestrup SK, Møller HJ, Graversen JH.

Immunobiology. 2011 Aug;216(8):882-90. doi: 10.1016/j.imbio.2011.02.001. Epub 2011 Feb 22.

PMID:
21458881
[PubMed - indexed for MEDLINE]
20.

CD163 binding to haptoglobin-hemoglobin complexes involves a dual-point electrostatic receptor-ligand pairing.

Nielsen MJ, Andersen CB, Moestrup SK.

J Biol Chem. 2013 Jun 28;288(26):18834-41. doi: 10.1074/jbc.M113.471060. Epub 2013 May 13.

PMID:
23671278
[PubMed - indexed for MEDLINE]
Free PMC Article

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