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Effect of aging on cytokine production in response to respiratory syncytial virus infection.

Looney RJ, Falsey AR, Walsh E, Campbell D.

J Infect Dis. 2002 Mar 1;185(5):682-5. Epub 2002 Feb 14.


T helper 1/T helper 2 cytokine imbalance in respiratory syncytial virus infection is associated with increased endogenous plasma cortisol.

Pinto RA, Arredondo SM, Bono MR, Gaggero AA, Díaz PV.

Pediatrics. 2006 May;117(5):e878-86. Epub 2006 Apr 17.


Cytokine production from peripheral blood mononuclear cells of mite allergen-sensitized atopic adults stimulated with respiratory syncytial virus and mite allergen.

Hirose H, Matsuse H, Tsuchida T, Fukahori S, Fukushima C, Mizuta Y, Kohno S.

Int Arch Allergy Immunol. 2008;146(2):149-55. doi: 10.1159/000113518. Epub 2008 Jan 18.


Peripheral blood mononuclear cells from infants hospitalized because of respiratory syncytial virus infection express T helper-1 and T helper-2 cytokines and CC chemokine messenger RNA.

Tripp RA, Moore D, Barskey A 4th, Jones L, Moscatiello C, Keyserling H, Anderson LJ.

J Infect Dis. 2002 May 15;185(10):1388-94. Epub 2002 Apr 30.


Age-related differences in pulmonary cytokine response to respiratory syncytial virus infection: modulation by anti-inflammatory and antiviral treatment.

Boukhvalova MS, Yim KC, Kuhn KH, Hemming JP, Prince GA, Porter DD, Blanco JC.

J Infect Dis. 2007 Feb 15;195(4):511-8. Epub 2007 Jan 4.


The balance between influenza- and RSV-specific CD4 T cells secreting IL-10 or IFNgamma in young and healthy-elderly subjects.

Lee FE, Walsh EE, Falsey AR, Liu N, Liu D, Divekar A, Snyder-Cappione JE, Mosmann TR.

Mech Ageing Dev. 2005 Nov;126(11):1223-9.


Respiratory syncytial virus decreases the capacity of myeloid dendritic cells to induce interferon-gamma in naïve T cells.

Bartz H, Türkel O, Hoffjan S, Rothoeft T, Gonschorek A, Schauer U.

Immunology. 2003 May;109(1):49-57.


Attenuation of respiratory syncytial virus-induced and RIG-I-dependent type I IFN responses in human neonates and very young children.

Marr N, Wang TI, Kam SH, Hu YS, Sharma AA, Lam A, Markowski J, Solimano A, Lavoie PM, Turvey SE.

J Immunol. 2014 Feb 1;192(3):948-57. doi: 10.4049/jimmunol.1302007. Epub 2014 Jan 3.


Adults 65 years old and older have reduced numbers of functional memory T cells to respiratory syncytial virus fusion protein.

Cherukuri A, Patton K, Gasser RA Jr, Zuo F, Woo J, Esser MT, Tang RS.

Clin Vaccine Immunol. 2013 Feb;20(2):239-47. doi: 10.1128/CVI.00580-12. Epub 2012 Dec 12.


Respiratory syncytial virus and influenza virus infections: observations from tissues of fatal infant cases.

Welliver TP, Reed JL, Welliver RC Sr.

Pediatr Infect Dis J. 2008 Oct;27(10 Suppl):S92-6. doi: 10.1097/INF.0b013e318168b706.


Differences in participation of innate and adaptive immunity to respiratory syncytial virus in adults and neonates.

Krishnan S, Craven M, Welliver RC, Ahmad N, Halonen M.

J Infect Dis. 2003 Aug 1;188(3):433-9. Epub 2003 Jul 10.


An aged mouse model for RSV infection and diminished CD8(+) CTL responses.

Zhang Y, Wang Y, Gilmore X, Xu K, Wyde PR, Mbawuike IN.

Exp Biol Med (Maywood). 2002 Feb;227(2):133-40.


Regulation of mite allergen-pulsed murine dendritic cells by respiratory syncytial virus.

Kondo Y, Matsuse H, Machida I, Kawano T, Saeki S, Tomari S, Obase Y, Fukushima C, Kohno S.

Am J Respir Crit Care Med. 2004 Feb 15;169(4):494-8. Epub 2003 Dec 4.


Respiratory syncytial virus-specific CD8+ memory T cell responses in elderly persons.

de Bree GJ, Heidema J, van Leeuwen EM, van Bleek GM, Jonkers RE, Jansen HM, van Lier RA, Out TA.

J Infect Dis. 2005 May 15;191(10):1710-8. Epub 2005 Apr 11.


Transforming growth factor beta is a major regulator of human neonatal immune responses following respiratory syncytial virus infection.

Thornburg NJ, Shepherd B, Crowe JE Jr.

J Virol. 2010 Dec;84(24):12895-902. doi: 10.1128/JVI.01273-10. Epub 2010 Oct 6.


Plasticity and virus specificity of the airway epithelial cell immune response during respiratory virus infection.

Ioannidis I, McNally B, Willette M, Peeples ME, Chaussabel D, Durbin JE, Ramilo O, Mejias A, Flaño E.

J Virol. 2012 May;86(10):5422-36. doi: 10.1128/JVI.06757-11. Epub 2012 Mar 7.

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