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Items: 1 to 20 of 251

1.

CD163: a signal receptor scavenging haptoglobin-hemoglobin complexes from plasma.

Graversen JH, Madsen M, Moestrup SK.

Int J Biochem Cell Biol. 2002 Apr;34(4):309-14. Review.

PMID:
11854028
2.

CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin.

Schaer DJ, Schaer CA, Buehler PW, Boykins RA, Schoedon G, Alayash AI, Schaffner A.

Blood. 2006 Jan 1;107(1):373-80. Epub 2005 Sep 27.

3.

Soluble macrophage-derived CD163: a homogenous ectodomain protein with a dissociable haptoglobin-hemoglobin binding.

Møller HJ, Nielsen MJ, Maniecki MB, Madsen M, Moestrup SK.

Immunobiology. 2010 May;215(5):406-12. doi: 10.1016/j.imbio.2009.05.003. Epub 2009 Jul 5.

PMID:
19581020
5.

Haptoglobin preserves the CD163 hemoglobin scavenger pathway by shielding hemoglobin from peroxidative modification.

Buehler PW, Abraham B, Vallelian F, Linnemayr C, Pereira CP, Cipollo JF, Jia Y, Mikolajczyk M, Boretti FS, Schoedon G, Alayash AI, Schaer DJ.

Blood. 2009 Mar 12;113(11):2578-86. doi: 10.1182/blood-2008-08-174466. Epub 2009 Jan 8.

6.

Genetically determined heterogeneity in hemoglobin scavenging and susceptibility to diabetic cardiovascular disease.

Asleh R, Marsh S, Shilkrut M, Binah O, Guetta J, Lejbkowicz F, Enav B, Shehadeh N, Kanter Y, Lache O, Cohen O, Levy NS, Levy AP.

Circ Res. 2003 Jun 13;92(11):1193-200. Epub 2003 May 15.

7.

CD163-expressing monocytes constitute an endotoxin-sensitive Hb clearance compartment within the vascular system.

Schaer CA, Vallelian F, Imhof A, Schoedon G, Schaer DJ.

J Leukoc Biol. 2007 Jul;82(1):106-10. Epub 2007 Apr 25.

8.

CD163 binding to haptoglobin-hemoglobin complexes involves a dual-point electrostatic receptor-ligand pairing.

Nielsen MJ, Andersen CB, Moestrup SK.

J Biol Chem. 2013 Jun 28;288(26):18834-41. doi: 10.1074/jbc.M113.471060. Epub 2013 May 13.

9.

Molecular characterization of the haptoglobin.hemoglobin receptor CD163. Ligand binding properties of the scavenger receptor cysteine-rich domain region.

Madsen M, Møller HJ, Nielsen MJ, Jacobsen C, Graversen JH, van den Berg T, Moestrup SK.

J Biol Chem. 2004 Dec 3;279(49):51561-7. Epub 2004 Sep 24.

10.

Identification of the haemoglobin scavenger receptor.

Kristiansen M, Graversen JH, Jacobsen C, Sonne O, Hoffman HJ, Law SK, Moestrup SK.

Nature. 2001 Jan 11;409(6817):198-201.

PMID:
11196644
11.

A previously unrecognized protein-protein interaction between TWEAK and CD163: potential biological implications.

Bover LC, Cardó-Vila M, Kuniyasu A, Sun J, Rangel R, Takeya M, Aggarwal BB, Arap W, Pasqualini R.

J Immunol. 2007 Jun 15;178(12):8183-94.

12.

A unique loop extension in the serine protease domain of haptoglobin is essential for CD163 recognition of the haptoglobin-hemoglobin complex.

Nielsen MJ, Petersen SV, Jacobsen C, Thirup S, Enghild JJ, Graversen JH, Moestrup SK.

J Biol Chem. 2007 Jan 12;282(2):1072-9. Epub 2006 Nov 13.

13.

Scavenger receptor CD163, a Jack-of-all-trades and potential target for cell-directed therapy.

Van Gorp H, Delputte PL, Nauwynck HJ.

Mol Immunol. 2010 Apr;47(7-8):1650-60. doi: 10.1016/j.molimm.2010.02.008. Epub 2010 Mar 17. Review.

PMID:
20299103
14.

Induction of the CD163-dependent haemoglobin uptake by macrophages as a novel anti-inflammatory action of glucocorticoids.

Schaer DJ, Boretti FS, Schoedon G, Schaffner A.

Br J Haematol. 2002 Oct;119(1):239-43.

PMID:
12358930
15.

Heme carrier protein (HCP-1) spatially interacts with the CD163 hemoglobin uptake pathway and is a target of inflammatory macrophage activation.

Schaer CA, Vallelian F, Imhof A, Schoedon G, Schaer DJ.

J Leukoc Biol. 2008 Feb;83(2):325-33. Epub 2007 Oct 18.

16.

Generation of a haptoglobin-hemoglobin complex-specific Fab antibody blocking the binding of the complex to CD163.

Horn IR, Nielsen MJ, Madsen M, Jacobsen C, Graversen JH, Moestrup SK.

Eur J Haematol. 2003 Oct;71(4):289-93. Erratum in: Eur J Haematol. 2004 Jan;72(1):77.

PMID:
12950239
17.

Corticosteroid enhances heme oxygenase-1 production by circulating monocytes by up-regulating hemoglobin scavenger receptor and amplifying the receptor-mediated uptake of hemoglobin-haptoglobin complex.

Yamazaki H, Ohta K, Tsukiji H, Toma T, Hashida Y, Ishizaki A, Saito T, Arai S, Koizumi S, Yachie A.

Biochem Biophys Res Commun. 2007 Jun 29;358(2):506-12. Epub 2007 Apr 30.

PMID:
17490617
18.
19.

Regulation of CD163 associated casein kinase II activity is haptoglobin genotype dependent.

Strauss M, Levy AP.

Mol Cell Biochem. 2008 Oct;317(1-2):131-5. doi: 10.1007/s11010-008-9840-3. Epub 2008 Jun 19.

PMID:
18563533
20.

The macrophage scavenger receptor CD163: endocytic properties of cytoplasmic tail variants.

Nielsen MJ, Madsen M, Møller HJ, Moestrup SK.

J Leukoc Biol. 2006 Apr;79(4):837-45. Epub 2006 Jan 24.

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