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Results: 1 to 20 of 96

1.

The use of retroviruses as pharmaceutical tools for target discovery and validation in the field of functional genomics.

Lorens JB, Sousa C, Bennett MK, Molineaux SM, Payan DG.

Curr Opin Biotechnol. 2001 Dec;12(6):613-21. Review.

PMID:
11849944
[PubMed - indexed for MEDLINE]
2.

Use of antisense oligonucleotides in functional genomics and target validation.

Ravichandran LV, Dean NM, Marcusson EG.

Oligonucleotides. 2004 Spring;14(1):49-64. Review.

PMID:
15104896
[PubMed - indexed for MEDLINE]
3.

Functional genomics and target validation approaches using antisense oligonucleotide technology.

Dean NM.

Curr Opin Biotechnol. 2001 Dec;12(6):622-5. Review.

PMID:
11849945
[PubMed - indexed for MEDLINE]
4.

Application of antisense oligonucleotides for gene functionalization and target validation.

Bennett CF, Cowsert LM.

Curr Opin Mol Ther. 1999 Jun;1(3):359-71. Review.

PMID:
11713801
[PubMed - indexed for MEDLINE]
5.

Strategies to identify potential therapeutic target sites in RNA.

L├╝tzelberger M, Kjems J.

Handb Exp Pharmacol. 2006;(173):243-59. Review.

PMID:
16594619
[PubMed - indexed for MEDLINE]
6.

Genome-wide screening for gene function using RNAi in mammalian cells.

Cullen LM, Arndt GM.

Immunol Cell Biol. 2005 Jun;83(3):217-23. Review.

PMID:
15877598
[PubMed - indexed for MEDLINE]
7.

Genome-wide application of RNAi to the discovery of potential drug targets.

Ito M, Kawano K, Miyagishi M, Taira K.

FEBS Lett. 2005 Oct 31;579(26):5988-95. Epub 2005 Aug 22. Review.

PMID:
16153642
[PubMed - indexed for MEDLINE]
Free Article
8.

Somatic transgenesis using retroviral vectors in the chicken embryo.

Ishii Y, Reese DE, Mikawa T.

Dev Dyn. 2004 Mar;229(3):630-42. Review.

PMID:
14991718
[PubMed - indexed for MEDLINE]
Free Article
9.

Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics.

Kitamura T, Koshino Y, Shibata F, Oki T, Nakajima H, Nosaka T, Kumagai H.

Exp Hematol. 2003 Nov;31(11):1007-14. Review.

PMID:
14585362
[PubMed - indexed for MEDLINE]
10.

Identification of metastasis-related genes in a mouse model using a library of randomized ribozymes.

Suyama E, Wadhwa R, Kaur K, Miyagishi M, Kaul SC, Kawasaki H, Taira K.

J Biol Chem. 2004 Sep 10;279(37):38083-6. Epub 2004 Jul 9. Erratum in: J Biol Chem. 2006 Jun 30;281(26):18264.

PMID:
15247279
[PubMed - indexed for MEDLINE]
Free Article
11.

Small interfering RNA production by enzymatic engineering of DNA (SPEED).

Luo B, Heard AD, Lodish HF.

Proc Natl Acad Sci U S A. 2004 Apr 13;101(15):5494-9. Epub 2004 Mar 15.

PMID:
15024103
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

A simple and efficient method for constructing an adenoviral cDNA expression library.

Hatanaka K, Ohnami S, Yoshida K, Miura Y, Aoyagi K, Sasaki H, Asaka M, Terada M, Yoshida T, Aoki K.

Mol Ther. 2003 Jul;8(1):158-66.

PMID:
12842439
[PubMed - indexed for MEDLINE]
13.

Ribozymes: applications to functional analysis and gene discovery.

Shiota M, Sano M, Miyagishi M, Taira K.

J Biochem. 2004 Aug;136(2):133-47. Review.

PMID:
15496583
[PubMed - indexed for MEDLINE]
Free Article
14.

Retroviral-mediated gene transfer. Applications in neurobiology.

Lo MM, Conrad MK, Mamalaki C, Kadan MJ.

Mol Neurobiol. 1988 Fall;2(3):155-82. Review.

PMID:
2855793
[PubMed - indexed for MEDLINE]
15.

Characterization of 954 bovine full-CDS cDNA sequences.

Harhay GP, Sonstegard TS, Keele JW, Heaton MP, Clawson ML, Snelling WM, Wiedmann RT, Van Tassell CP, Smith TP.

BMC Genomics. 2005 Nov 23;6:166.

PMID:
16305752
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

In vivo drug target discovery: identifying the best targets from the genome.

Walke DW, Han C, Shaw J, Wann E, Zambrowicz B, Sands A.

Curr Opin Biotechnol. 2001 Dec;12(6):626-31. Review.

PMID:
11849946
[PubMed - indexed for MEDLINE]
17.

Functional genomics to new drug targets.

Kramer R, Cohen D.

Nat Rev Drug Discov. 2004 Nov;3(11):965-72. Review.

PMID:
15520818
[PubMed - indexed for MEDLINE]
18.

Discovery of functional genes in the post-genome era by novel RNA-protein hybrid ribozymes.

Kawasaki H, Taira K.

Nucleic Acids Res Suppl. 2001;(1):133-4.

PMID:
12836300
[PubMed - indexed for MEDLINE]
Free Article
19.

Functional cloning using pFB retroviral cDNA expression libraries.

Felts KA, Chen K, Zaharee K, Sundar L, Limjoco J, Miller A, Vaillancourt P.

Mol Biotechnol. 2002 Sep;22(1):25-32.

PMID:
12353912
[PubMed - indexed for MEDLINE]
20.

High-content screening of functional genomic libraries.

Rines DR, Tu B, Miraglia L, Welch GL, Zhang J, Hull MV, Orth AP, Chanda SK.

Methods Enzymol. 2006;414:530-65.

PMID:
17110210
[PubMed - indexed for MEDLINE]

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