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Results: 1 to 20 of 933

1.

Structural analyses reveal two distinct families of nucleoside phosphorylases.

Pugmire MJ, Ealick SE.

Biochem J. 2002 Jan 1;361(Pt 1):1-25. Review.

PMID:
11743878
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The crystal structure of Escherichia coli purine nucleoside phosphorylase: a comparison with the human enzyme reveals a conserved topology.

Mao C, Cook WJ, Zhou M, Koszalka GW, Krenitsky TA, Ealick SE.

Structure. 1997 Oct 15;5(10):1373-83.

PMID:
9351810
[PubMed - indexed for MEDLINE]
3.

Unexpected sequence similarity between nucleosidases and phosphoribosyltransferases of different specificity.

Mushegian AR, Koonin EV.

Protein Sci. 1994 Jul;3(7):1081-8.

PMID:
7920254
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Structure of E. coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase reveals similarity to the purine nucleoside phosphorylases.

Lee JE, Cornell KA, Riscoe MK, Howell PL.

Structure. 2001 Oct;9(10):941-53.

PMID:
11591349
[PubMed - indexed for MEDLINE]
5.

The structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase at 1.7 A resolution provides insights into substrate binding and catalysis.

Appleby TC, Erion MD, Ealick SE.

Structure. 1999 Jun 15;7(6):629-41.

PMID:
10404592
[PubMed - indexed for MEDLINE]
6.

Crystal structure of calf spleen purine nucleoside phosphorylase with two full trimers in the asymmetric unit: important implications for the mechanism of catalysis.

Bzowska A, Koellner G, Wielgus-Kutrowska B, Stroh A, Raszewski G, Holý A, Steiner T, Frank J.

J Mol Biol. 2004 Sep 17;342(3):1015-32.

PMID:
15342253
[PubMed - indexed for MEDLINE]
7.

Unraveling the structural and functional differences between purine nucleoside phosphorylase and 5'-deoxy-5'-methylthioadenosine phosphorylase from the archaeon Pyrococcus furiosus.

Cacciapuoti G, Marabotti A, Fuccio F, Porcelli M.

Biochim Biophys Acta. 2011 Oct;1814(10):1358-66. doi: 10.1016/j.bbapap.2011.06.001. Epub 2011 Jun 13.

PMID:
21683167
[PubMed - indexed for MEDLINE]
8.

Crystal structure of the purine nucleoside phosphorylase (PNP) from Cellulomonas sp. and its implication for the mechanism of trimeric PNPs.

Tebbe J, Bzowska A, Wielgus-Kutrowska B, Schröder W, Kazimierczuk Z, Shugar D, Saenger W, Koellner G.

J Mol Biol. 1999 Dec 17;294(5):1239-55.

PMID:
10600382
[PubMed - indexed for MEDLINE]
9.

The purine nucleoside phosphorylase from Trichomonas vaginalis is a homologue of the bacterial enzyme.

Munagala N, Wang CC.

Biochemistry. 2002 Aug 20;41(33):10382-9.

PMID:
12173924
[PubMed - indexed for MEDLINE]
10.

Structures for the potential drug target purine nucleoside phosphorylase from Schistosoma mansoni causal agent of schistosomiasis.

Pereira HD, Franco GR, Cleasby A, Garratt RC.

J Mol Biol. 2005 Oct 28;353(3):584-99. Epub 2005 Sep 2.

PMID:
16182308
[PubMed - indexed for MEDLINE]
11.

The evolution of catalytic residues and enzyme mechanism within the bacterial nucleoside phosphorylase superfamily 1.

Konrad A, Piškur J, Liberles DA.

Gene. 2012 Dec 1;510(2):154-61. doi: 10.1016/j.gene.2012.08.046. Epub 2012 Sep 3.

PMID:
22967797
[PubMed - indexed for MEDLINE]
12.

Structural comparison of MTA phosphorylase and MTA/AdoHcy nucleosidase explains substrate preferences and identifies regions exploitable for inhibitor design.

Lee JE, Settembre EC, Cornell KA, Riscoe MK, Sufrin JR, Ealick SE, Howell PL.

Biochemistry. 2004 May 11;43(18):5159-69.

PMID:
15122881
[PubMed - indexed for MEDLINE]
13.

The crystal structure of pyrimidine nucleoside phosphorylase in a closed conformation.

Pugmire MJ, Ealick SE.

Structure. 1998 Nov 15;6(11):1467-79.

PMID:
9817849
[PubMed - indexed for MEDLINE]
14.

Purine nucleoside phosphorylase. 2. Catalytic mechanism.

Erion MD, Stoeckler JD, Guida WC, Walter RL, Ealick SE.

Biochemistry. 1997 Sep 30;36(39):11735-48.

PMID:
9305963
[PubMed - indexed for MEDLINE]
15.

Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene.

Dandanell G, Szczepanowski RH, Kierdaszuk B, Shugar D, Bochtler M.

J Mol Biol. 2005 Apr 22;348(1):113-25.

PMID:
15808857
[PubMed - indexed for MEDLINE]
16.

Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces.

Shi W, Basso LA, Santos DS, Tyler PC, Furneaux RH, Blanchard JS, Almo SC, Schramm VL.

Biochemistry. 2001 Jul 27;40(28):8204-15.

PMID:
11444966
[PubMed - indexed for MEDLINE]
17.

Structural basis for selective inhibition of purine nucleoside phosphorylase from Schistosoma mansoni: kinetic and structural studies.

Castilho MS, Postigo MP, Pereira HM, Oliva G, Andricopulo AD.

Bioorg Med Chem. 2010 Feb 15;18(4):1421-7. doi: 10.1016/j.bmc.2010.01.022. Epub 2010 Jan 18.

PMID:
20129792
[PubMed - indexed for MEDLINE]
18.

Crystal structure of human purine nucleoside phosphorylase at 2.3A resolution.

de Azevedo WF Jr, Canduri F, dos Santos DM, Silva RG, de Oliveira JS, de Carvalho LP, Basso LA, Mendes MA, Palma MS, Santos DS.

Biochem Biophys Res Commun. 2003 Aug 29;308(3):545-52.

PMID:
12914785
[PubMed - indexed for MEDLINE]
19.

The crystal structure of anthranilate phosphoribosyltransferase from the enterobacterium Pectobacterium carotovorum.

Kim C, Xuong NH, Edwards S, Madhusudan, Yee MC, Spraggon G, Mills SE.

FEBS Lett. 2002 Jul 17;523(1-3):239-46.

PMID:
12123839
[PubMed - indexed for MEDLINE]
20.

Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors.

Ealick SE, Babu YS, Bugg CE, Erion MD, Guida WC, Montgomery JA, Secrist JA 3rd.

Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11540-4. Erratum in: Proc Natl Acad Sci U S A 1992 Oct 15;89(20):9974.

PMID:
1763067
[PubMed - indexed for MEDLINE]
Free PMC Article
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