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Items: 1 to 20 of 756


Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis.

Eischen CM, Roussel MF, Korsmeyer SJ, Cleveland JL.

Mol Cell Biol. 2001 Nov;21(22):7653-62.


Loss of one allele of ARF rescues Mdm2 haploinsufficiency effects on apoptosis and lymphoma development.

Eischen CM, Alt JR, Wang P.

Oncogene. 2004 Nov 25;23(55):8931-40.


Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis.

Eischen CM, Weber JD, Roussel MF, Sherr CJ, Cleveland JL.

Genes Dev. 1999 Oct 15;13(20):2658-69.


MIF loss impairs Myc-induced lymphomagenesis.

Talos F, Mena P, Fingerle-Rowson G, Moll U, Petrenko O.

Cell Death Differ. 2005 Oct;12(10):1319-28.


Bax accelerates tumorigenesis in p53-deficient mice.

Knudson CM, Johnson GM, Lin Y, Korsmeyer SJ.

Cancer Res. 2001 Jan 15;61(2):659-65.


Elevated Mdm2 expression induces chromosomal instability and confers a survival and growth advantage to B cells.

Wang P, Lushnikova T, Odvody J, Greiner TC, Jones SN, Eischen CM.

Oncogene. 2008 Mar 6;27(11):1590-8. Epub 2007 Sep 10.


Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis.

Hemmati PG, Gillissen B, von Haefen C, Wendt J, Stärck L, Güner D, Dörken B, Daniel PT.

Oncogene. 2002 May 9;21(20):3149-61.


Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by E2f1 loss.

Baudino TA, Maclean KH, Brennan J, Parganas E, Yang C, Aslanian A, Lees JA, Sherr CJ, Roussel MF, Cleveland JL.

Mol Cell. 2003 Apr;11(4):905-14.


Survival and death of prelymphomatous B-cells from N-myc/bcl-2 double transgenic mice correlates with the regulation of intracellular Ca2+ fluxes.

Zörnig M, Busch G, Beneke R, Gulbins E, Lang F, Ma A, Korsmeyer S, Möröy T.

Oncogene. 1995 Nov 16;11(10):2165-74.


Mdm2 haplo-insufficiency profoundly inhibits Myc-induced lymphomagenesis.

Alt JR, Greiner TC, Cleveland JL, Eischen CM.

EMBO J. 2003 Mar 17;22(6):1442-50.


c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL.

Maclean KH, Keller UB, Rodriguez-Galindo C, Nilsson JA, Cleveland JL.

Mol Cell Biol. 2003 Oct;23(20):7256-70.


Loss of Bax alters tumor spectrum and tumor numbers in ARF-deficient mice.

Eischen CM, Rehg JE, Korsmeyer SJ, Cleveland JL.

Cancer Res. 2002 Apr 1;62(7):2184-91.


Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation.

Nilsson JA, Keller UB, Baudino TA, Yang C, Norton S, Old JA, Nilsson LM, Neale G, Kramer DL, Porter CW, Cleveland JL.

Cancer Cell. 2005 May;7(5):433-44.


Potential synergism of Bim with p53 in mice with Myc‑induced lymphoma in a mouse lymphoma model.

Shang Q, Zhang D, Guo C, Lin Q, Guo Z, Deng C.

Mol Med Rep. 2012 Jun;5(6):1401-8. doi: 10.3892/mmr.2012.844. Epub 2012 Mar 22.


c-Myc sensitization to oxygen deprivation-induced cell death is dependent on Bax/Bak, but is independent of p53 and hypoxia-inducible factor-1.

Brunelle JK, Santore MT, Budinger GR, Tang Y, Barrett TA, Zong WX, Kandel E, Keith B, Simon MC, Thompson CB, Hay N, Chandel NS.

J Biol Chem. 2004 Feb 6;279(6):4305-12. Epub 2003 Nov 19.


Growth suppression by a p14(ARF) exon 1beta adenovirus in human tumor cell lines of varying p53 and Rb status.

Saadatmandi N, Tyler T, Huang Y, Haghighi A, Frost G, Borgstrom P, Gjerset RA.

Cancer Gene Ther. 2002 Oct;9(10):830-9.

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