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Items: 1 to 20 of 97


IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding.

Hymowitz SG, Filvaroff EH, Yin JP, Lee J, Cai L, Risser P, Maruoka M, Mao W, Foster J, Kelley RF, Pan G, Gurney AL, de Vos AM, Starovasnik MA.

EMBO J. 2001 Oct 1;20(19):5332-41.


Cloning and characterization of IL-17B and IL-17C, two new members of the IL-17 cytokine family.

Li H, Chen J, Huang A, Stinson J, Heldens S, Foster J, Dowd P, Gurney AL, Wood WI.

Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):773-8.


Structure and function of interleukin-17 family cytokines.

Zhang X, Angkasekwinai P, Dong C, Tang H.

Protein Cell. 2011 Jan;2(1):26-40. doi: 10.1007/s13238-011-1006-5. Epub 2011 Feb 20. Review.


Structure of IL-17A in complex with a potent, fully human neutralizing antibody.

Gerhardt S, Abbott WM, Hargreaves D, Pauptit RA, Davies RA, Needham MR, Langham C, Barker W, Aziz A, Snow MJ, Dawson S, Welsh F, Wilkinson T, Vaugan T, Beste G, Bishop S, Popovic B, Rees G, Sleeman M, Tuske SJ, Coales SJ, Hamuro Y, Russell C.

J Mol Biol. 2009 Dec 18;394(5):905-21. doi: 10.1016/j.jmb.2009.10.008. Epub 2009 Oct 14.


IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1.

Lee J, Ho WH, Maruoka M, Corpuz RT, Baldwin DT, Foster JS, Goddard AD, Yansura DG, Vandlen RL, Wood WI, Gurney AL.

J Biol Chem. 2001 Jan 12;276(2):1660-4.


Interleukin-17 family and IL-17 receptors.

Moseley TA, Haudenschild DR, Rose L, Reddi AH.

Cytokine Growth Factor Rev. 2003 Apr;14(2):155-74. Review.


The human IL-17F/IL-17A heterodimeric cytokine signals through the IL-17RA/IL-17RC receptor complex.

Wright JF, Bennett F, Li B, Brooks J, Luxenberg DP, Whitters MJ, Tomkinson KN, Fitz LJ, Wolfman NM, Collins M, Dunussi-Joannopoulos K, Chatterjee-Kishore M, Carreno BM.

J Immunol. 2008 Aug 15;181(4):2799-805.


A novel cytokine receptor-ligand pair. Identification, molecular characterization, and in vivo immunomodulatory activity.

Shi Y, Ullrich SJ, Zhang J, Connolly K, Grzegorzewski KJ, Barber MC, Wang W, Wathen K, Hodge V, Fisher CL, Olsen H, Ruben SM, Knyazev I, Cho YH, Kao V, Wilkinson KA, Carrell JA, Ebner R.

J Biol Chem. 2000 Jun 23;275(25):19167-76.


Crystal structure of recombinant human interleukin-22.

Nagem RA, Colau D, Dumoutier L, Renauld JC, Ogata C, Polikarpov I.

Structure. 2002 Aug;10(8):1051-62.


Cutting edge: IL-17F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production.

Starnes T, Robertson MJ, Sledge G, Kelich S, Nakshatri H, Broxmeyer HE, Hromas R.

J Immunol. 2001 Oct 15;167(8):4137-40.


Structural basis of receptor sharing by interleukin 17 cytokines.

Ely LK, Fischer S, Garcia KC.

Nat Immunol. 2009 Dec;10(12):1245-51. doi: 10.1038/ni.1813. Epub 2009 Oct 18.


A novel interleukin-17 receptor-like protein identified in human umbilical vein endothelial cells antagonizes basic fibroblast growth factor-induced signaling.

Yang RB, Ng CK, Wasserman SM, Kömüves LG, Gerritsen ME, Topper JN.

J Biol Chem. 2003 Aug 29;278(35):33232-8. Epub 2003 Jun 12.


Crystal structures of interleukin 17A and its complex with IL-17 receptor A.

Liu S, Song X, Chrunyk BA, Shanker S, Hoth LR, Marr ES, Griffor MC.

Nat Commun. 2013;4:1888. doi: 10.1038/ncomms2880.


Molecular characterization of the human interleukin (IL)-17 receptor.

Yao Z, Spriggs MK, Derry JM, Strockbine L, Park LS, VandenBos T, Zappone JD, Painter SL, Armitage RJ.

Cytokine. 1997 Nov;9(11):794-800.


Exchanging interleukin-8 and melanoma growth-stimulating activity receptor binding specificities.

Lowman HB, Slagle PH, DeForge LE, Wirth CM, Gillece-Castro BL, Bourell JH, Fairbrother WJ.

J Biol Chem. 1996 Jun 14;271(24):14344-52.


Identification of an interleukin 17F/17A heterodimer in activated human CD4+ T cells.

Wright JF, Guo Y, Quazi A, Luxenberg DP, Bennett F, Ross JF, Qiu Y, Whitters MJ, Tomkinson KN, Dunussi-Joannopoulos K, Carreno BM, Collins M, Wolfman NM.

J Biol Chem. 2007 May 4;282(18):13447-55. Epub 2007 Mar 13.


Interleukin-17F affects cartilage matrix turnover by increasing the expression of collagenases and stromelysin-1 and by decreasing the expression of their inhibitors and extracellular matrix components in chondrocytes.

Tanigawa S, Aida Y, Kawato T, Honda K, Nakayama G, Motohashi M, Suzuki N, Ochiai K, Matsumura H, Maeno M.

Cytokine. 2011 Nov;56(2):376-86. doi: 10.1016/j.cyto.2011.08.015. Epub 2011 Aug 31.


Interleukin-3 binding to the murine betaIL-3 and human betac receptors involves functional epitopes formed by domains 1 and 4 of different protein chains.

Murphy JM, Ford SC, Olsen JE, Gustin SE, Jeffrey PD, Ollis DL, Young IG.

J Biol Chem. 2004 Jun 18;279(25):26500-8. Epub 2004 Apr 1.


Antagonistic RNA aptamer specific to a heterodimeric form of human interleukin-17A/F.

Adachi H, Ishiguro A, Hamada M, Sakota E, Asai K, Nakamura Y.

Biochimie. 2011 Jul;93(7):1081-8. doi: 10.1016/j.biochi.2011.04.003. Epub 2011 Apr 19.

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