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Results: 1 to 20 of 109

Similar articles for PubMed (Select 11551524)

1.

Quantification and cellular localization of expression in human skin of genes encoding flavin-containing monooxygenases and cytochromes P450.

Janmohamed A, Dolphin CT, Phillips IR, Shephard EA.

Biochem Pharmacol. 2001 Sep 15;62(6):777-86.

PMID:
11551524
2.

Molecular and functional characterization of flavin-containing monooxygenases in cynomolgus macaque.

Uno Y, Shimizu M, Yamazaki H.

Biochem Pharmacol. 2013 Jun 15;85(12):1837-47. doi: 10.1016/j.bcp.2013.04.012. Epub 2013 Apr 23.

PMID:
23623750
3.

Xenobiotic metabolism capacities of human skin in comparison with a 3D epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: activating enzymes (Phase I).

Götz C, Pfeiffer R, Tigges J, Blatz V, Jäckh C, Freytag EM, Fabian E, Landsiedel R, Merk HF, Krutmann J, Edwards RJ, Pease C, Goebel C, Hewitt N, Fritsche E.

Exp Dermatol. 2012 May;21(5):358-63. doi: 10.1111/j.1600-0625.2012.01486.x.

PMID:
22509833
4.

Regioselective oxidation of phospho-NSAIDs by human cytochrome P450 and flavin monooxygenase isoforms: implications for their pharmacokinetic properties and safety.

Xie G, Wong CC, Cheng KW, Huang L, Constantinides PP, Rigas B.

Br J Pharmacol. 2012 Sep;167(1):222-32. doi: 10.1111/j.1476-5381.2012.01982.x.

5.

CYP4F22 is highly expressed at the site and timing of onset of keratinization during skin development.

Sasaki K, Akiyama M, Yanagi T, Sakai K, Miyamura Y, Sato M, Shimizu H.

J Dermatol Sci. 2012 Feb;65(2):156-8. doi: 10.1016/j.jdermsci.2011.12.006. Epub 2011 Dec 13. No abstract available.

PMID:
22209317
6.

Characterization of enzyme activities of Cytochrome P450 enzymes, Flavin-dependent monooxygenases, N-acetyltransferases and UDP-glucuronyltransferases in human reconstructed epidermis and full-thickness skin models.

Jäckh C, Blatz V, Fabian E, Guth K, van Ravenzwaay B, Reisinger K, Landsiedel R.

Toxicol In Vitro. 2011 Sep;25(6):1209-14. doi: 10.1016/j.tiv.2011.03.012. Epub 2011 Mar 22.

PMID:
21435388
7.

The potential of knockout mouse lines in defining the role of flavin-containing monooxygenases in drug metabolism.

Shephard EA, Phillips IR.

Expert Opin Drug Metab Toxicol. 2010 Sep;6(9):1083-94. doi: 10.1517/17425255.2010.503705. Review.

PMID:
20629583
8.

Flavin-containing monooxygenase 1-catalysed N,N-dimethylamphetamine N-oxidation.

Lee SK, Kang MJ, Jin C, In MK, Kim DH, Yoo HH.

Xenobiotica. 2009 Sep;39(9):680-6. doi: 10.1080/00498250902998699.

PMID:
19552509
9.

Aryl hydrocarbon receptor is an ozone sensor in human skin.

Afaq F, Zaid MA, Pelle E, Khan N, Syed DN, Matsui MS, Maes D, Mukhtar H.

J Invest Dermatol. 2009 Oct;129(10):2396-403. doi: 10.1038/jid.2009.85. Epub 2009 Jun 18.

10.

Expression profiles of phases 1 and 2 metabolizing enzymes in human skin and the reconstructed skin models Episkin and full thickness model from Episkin.

Luu-The V, Duche D, Ferraris C, Meunier JR, Leclaire J, Labrie F.

J Steroid Biochem Mol Biol. 2009 Sep;116(3-5):178-86. doi: 10.1016/j.jsbmb.2009.05.011. Epub 2009 May 29.

PMID:
19482084
11.

Effect of hyperosmotic conditions on flavin-containing monooxygenase activity, protein and mRNA expression in rat kidney.

Rodríguez-Fuentes G, Coburn C, Currás-Collazo M, Guillén G, Schlenk D.

Toxicol Lett. 2009 Jun 1;187(2):115-8. doi: 10.1016/j.toxlet.2009.02.006. Epub 2009 Feb 20.

12.

Differential localization of flavin-containing monooxygenase (FMO) isoforms 1, 3, and 4 in rat liver and kidney and evidence for expression of FMO4 in mouse, rat, and human liver and kidney microsomes.

Novick RM, Mitzey AM, Brownfield MS, Elfarra AA.

J Pharmacol Exp Ther. 2009 Jun;329(3):1148-55. doi: 10.1124/jpet.109.152058. Epub 2009 Mar 23.

13.

Deletion of the mouse Fmo1 gene results in enhanced pharmacological behavioural responses to imipramine.

Hernandez D, Janmohamed A, Chandan P, Omar BA, Phillips IR, Shephard EA.

Pharmacogenet Genomics. 2009 Apr;19(4):289-99. doi: 10.1097/FPC.0b013e328328d507.

PMID:
19262426
14.

The involvement of cytochrome p450 (CYP) 26 in the retinoic acid metabolism of human epidermal keratinocytes.

Pavez Loriè E, Li H, Vahlquist A, Törmä H.

Biochim Biophys Acta. 2009 Mar;1791(3):220-8. doi: 10.1016/j.bbalip.2008.12.004. Epub 2008 Dec 24.

PMID:
19171200
15.

Use of mRNA expression to detect the induction of drug metabolising enzymes in rat and human hepatocytes.

Richert L, Tuschl G, Abadie C, Blanchard N, Pekthong D, Mantion G, Weber JC, Mueller SO.

Toxicol Appl Pharmacol. 2009 Feb 15;235(1):86-96. doi: 10.1016/j.taap.2008.11.019. Epub 2008 Dec 10.

PMID:
19118567
16.

Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells.

Dauchy S, Miller F, Couraud PO, Weaver RJ, Weksler B, Romero IA, Scherrmann JM, De Waziers I, Declèves X.

Biochem Pharmacol. 2009 Mar 1;77(5):897-909. doi: 10.1016/j.bcp.2008.11.001. Epub 2008 Nov 12.

PMID:
19041851
17.

Biotransformation of drugs in human skin.

Svensson CK.

Drug Metab Dispos. 2009 Feb;37(2):247-53. doi: 10.1124/dmd.108.024794. Epub 2008 Nov 12.

18.

The participation of human hepatic P450 isoforms, flavin-containing monooxygenases and aldehyde oxidase in the biotransformation of the insecticide fenthion.

Leoni C, Buratti FM, Testai E.

Toxicol Appl Pharmacol. 2008 Dec 1;233(2):343-52. doi: 10.1016/j.taap.2008.09.004. Epub 2008 Sep 19.

PMID:
18845175
19.

Expression and function of cytochrome p450-dependent enzymes in human skin cells.

Baron JM, Wiederholt T, Heise R, Merk HF, Bickers DR.

Curr Med Chem. 2008;15(22):2258-64. Review.

PMID:
18781947
20.

Aryl hydrocarbon receptor-dependent induction of flavin-containing monooxygenase mRNAs in mouse liver.

Celius T, Roblin S, Harper PA, Matthews J, Boutros PC, Pohjanvirta R, Okey AB.

Drug Metab Dispos. 2008 Dec;36(12):2499-505. doi: 10.1124/dmd.108.023457. Epub 2008 Sep 2.

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