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Results: 1 to 20 of 211

1.

Measurement of acetaminophen-protein adducts in children and adolescents with acetaminophen overdoses. .

James LP, Farrar HC, Sullivan JE, Givens TG, Kearns GL, Wasserman GS, Walson PD, Hinson JA, Pumford NR; Pediatric Pharmacology Research Unit Network, NICHD.

J Clin Pharmacol. 2001 Aug;41(8):846-51.

PMID:
11504272
[PubMed - indexed for MEDLINE]
2.

Determination of acetaminophen-protein adducts in mouse liver and serum and human serum after hepatotoxic doses of acetaminophen using high-performance liquid chromatography with electrochemical detection.

Muldrew KL, James LP, Coop L, McCullough SS, Hendrickson HP, Hinson JA, Mayeux PR.

Drug Metab Dispos. 2002 Apr;30(4):446-51.

PMID:
11901099
[PubMed - indexed for MEDLINE]
Free Article
3.

Elevation of serum interleukin 8 levels in acetaminophen overdose in children and adolescents.

James LP, Farrar HC, Darville TL, Sullivan JE, Givens TG, Kearns GL, Wasserman GS, Simpson PM, Hinson JA; Pediatric Pharmacology Research Unit Network, National Institute of Child Health and Human Development.

Clin Pharmacol Ther. 2001 Sep;70(3):280-6.

PMID:
11557916
[PubMed - indexed for MEDLINE]
4.

Prospective evaluation of repeated supratherapeutic acetaminophen (paracetamol) ingestion.

Daly FF, O'Malley GF, Heard K, Bogdan GM, Dart RC.

Ann Emerg Med. 2004 Oct;44(4):393-8.

PMID:
15459622
[PubMed - indexed for MEDLINE]
5.

Cytokines and toxicity in acetaminophen overdose.

James LP, Simpson PM, Farrar HC, Kearns GL, Wasserman GS, Blumer JL, Reed MD, Sullivan JE, Hinson JA.

J Clin Pharmacol. 2005 Oct;45(10):1165-71.

PMID:
16172181
[PubMed - indexed for MEDLINE]
6.

Therapeutic misadventures with acetaminophen: hepatoxicity after multiple doses in children.

Heubi JE, Barbacci MB, Zimmerman HJ.

J Pediatr. 1998 Jan;132(1):22-7. Review.

PMID:
9469995
[PubMed - indexed for MEDLINE]
7.

Acetaminophen overdose in children and adolescents.

Lin SJ, Chao HC, Huang JL, Lin TY, Hsieh KH.

Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi. 1997 Nov-Dec;38(6):448-53.

PMID:
9473817
[PubMed - indexed for MEDLINE]
8.

Evaluation of occult acetaminophen hepatotoxicity in hospitalized children receiving acetaminophen. Pediatric Pharmacology Research Unit Network.

James LP, Wilson JT, Simar R, Farrar HC, Kearns GL, Simpson PM, Hinson JA, Pumford NR; Pediatric Pharmacology Research Unit Network.

Clin Pediatr (Phila). 2001 May;40(5):243-8.

PMID:
11388672
[PubMed - indexed for MEDLINE]
9.

Predictors of outcome after acetaminophen poisoning in children and adolescents.

James LP, Wells E, Beard RH, Farrar HC.

J Pediatr. 2002 May;140(5):522-6.

PMID:
12032516
[PubMed - indexed for MEDLINE]
10.

Hepatotoxicity despite early administration of intravenous N-acetylcysteine for acute acetaminophen overdose.

Doyon S, Klein-Schwartz W.

Acad Emerg Med. 2009 Jan;16(1):34-9. doi: 10.1111/j.1553-2712.2008.00296.x. Epub 2008 Nov 8.

PMID:
19007345
[PubMed - indexed for MEDLINE]
11.

Detection of acetaminophen protein adducts in children with acute liver failure of indeterminate cause.

James LP, Alonso EM, Hynan LS, Hinson JA, Davern TJ, Lee WM, Squires RH; Pediatric Acute Liver Failure Study Group.

Pediatrics. 2006 Sep;118(3):e676-81.

PMID:
16950959
[PubMed - indexed for MEDLINE]
Free Article
12.

Acetaminophen-associated hepatic injury: evaluation of acetaminophen protein adducts in children and adolescents with acetaminophen overdose.

James LP, Capparelli EV, Simpson PM, Letzig L, Roberts D, Hinson JA, Kearns GL, Blumer JL, Sullivan JE; Network of Pediatric Pharmacology Research Units, National Institutes of Child Health and Human Development.

Clin Pharmacol Ther. 2008 Dec;84(6):684-90. doi: 10.1038/clpt.2008.190. Epub 2008 Oct 15.

PMID:
18923390
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Multiplying the serum aminotransferase by the acetaminophen concentration to predict toxicity following overdose.

Sivilotti ML, Green TJ, Langmann C, Yarema M, Juurlink D, Johnson D.

Clin Toxicol (Phila). 2010 Oct;48(8):793-9. doi: 10.3109/15563650.2010.523829. Epub 2010 Oct 8.

PMID:
20932103
[PubMed - indexed for MEDLINE]
14.

When do the aminotransferases rise after acute acetaminophen overdose?

Green TJ, Sivilotti ML, Langmann C, Yarema M, Juurlink D, Burns MJ, Johnson DW.

Clin Toxicol (Phila). 2010 Oct;48(8):787-92. doi: 10.3109/15563650.2010.523828.

PMID:
20969501
[PubMed - indexed for MEDLINE]
15.

Pretreatment of mice with macrophage inactivators decreases acetaminophen hepatotoxicity and the formation of reactive oxygen and nitrogen species.

Michael SL, Pumford NR, Mayeux PR, Niesman MR, Hinson JA.

Hepatology. 1999 Jul;30(1):186-95.

PMID:
10385655
[PubMed - indexed for MEDLINE]
16.

Shorter duration of oral N-acetylcysteine therapy for acute acetaminophen overdose.

Woo OF, Mueller PD, Olson KR, Anderson IB, Kim SY.

Ann Emerg Med. 2000 Apr;35(4):363-8.

PMID:
10736123
[PubMed - indexed for MEDLINE]
17.

Chronic acetaminophen overdosing in children: risk assessment and management.

Sztajnkrycer MJ, Bond GR.

Curr Opin Pediatr. 2001 Apr;13(2):177-82. Review.

PMID:
11317062
[PubMed - indexed for MEDLINE]
18.

Mechanism of acetaminophen-induced hepatotoxicity: covalent binding versus oxidative stress.

Gibson JD, Pumford NR, Samokyszyn VM, Hinson JA.

Chem Res Toxicol. 1996 Apr-May;9(3):580-5.

PMID:
8728501
[PubMed - indexed for MEDLINE]
19.

Abnormal serum transaminases following therapeutic doses of acetaminophen in the absence of known risk factors.

Kwan D, Bartle WR, Walker SE.

Dig Dis Sci. 1995 Sep;40(9):1951-5.

PMID:
7555449
[PubMed - indexed for MEDLINE]
20.

Nitrotyrosine-protein adducts in hepatic centrilobular areas following toxic doses of acetaminophen in mice.

Hinson JA, Pike SL, Pumford NR, Mayeux PR.

Chem Res Toxicol. 1998 Jun;11(6):604-7.

PMID:
9625727
[PubMed - indexed for MEDLINE]

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