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Items: 1 to 20 of 102

1.

The applicability of rat and human liver slices to the study of mechanisms of hepatic drug uptake.

Olinga P, Hof IH, Merema MT, Smit M, de Jager MH, Swart PJ, Slooff MJ, Meijer DK, Groothuis GM.

J Pharmacol Toxicol Methods. 2001 Jan-Feb;45(1):55-63.

PMID:
11489665
2.

Massive targeting of liposomes, surface-modified with anionized albumins, to hepatic endothelial cells.

Kamps JA, Morselt HW, Swart PJ, Meijer DK, Scherphof GL.

Proc Natl Acad Sci U S A. 1997 Oct 14;94(21):11681-5.

3.

Hepatic and intrahepatic targeting of an anti-inflammatory agent with human serum albumin and neoglycoproteins as carrier molecules.

Franssen EJ, Jansen RW, Vaalburg M, Meijer DK.

Biochem Pharmacol. 1993 Mar 24;45(6):1215-26.

PMID:
8466542
4.

Comparative pharmacokinetic, immunologic and hematologic studies on the anti-HIV-1/2 compounds aconitylated and succinylated HSA.

Swart PJ, Beljaars E, Smit C, Pasma A, Schuitemaker H, Meijer DK.

J Drug Target. 1996;4(2):109-16.

PMID:
8894971
5.

Coupling of the antiviral drug ara-AMP to lactosaminated albumin leads to specific uptake in rat and human hepatocytes.

Jansen RW, Kruijt JK, van Berkel TJ, Meijer DK.

Hepatology. 1993 Jul;18(1):146-52.

PMID:
7686877
7.
8.

Characterization of the uptake of rocuronium and digoxin in human hepatocytes: carrier specificity and comparison with in vivo data.

Olinga P, Merema M, Hof IH, Slooff MJ, Proost JH, Meijer DK, Groothuis GM.

J Pharmacol Exp Ther. 1998 May;285(2):506-10.

9.

Prediction of the pharmacokinetics of succinylated human serum albumin in man from in vivo disposition data in animals and in vitro liver slice incubations.

Proost JH, Beljaars L, Olinga P, Swart PJ, Kuipers ME, Reker-Smit C, Groothuis GM, Meijer DK.

Eur J Pharm Sci. 2006 Feb;27(2-3):123-32. Epub 2005 Oct 10.

PMID:
16219448
10.

The influence of charge clustering on the anti-HIV-1 activity and in vivo distribution of negatively charged albumins.

Beljaars L, Floris R, Berkhout B, Smit C, Meijer DK, Molema G.

Biochem Pharmacol. 2002 May 1;63(9):1663-73.

PMID:
12007569
11.

Albumin modified with mannose 6-phosphate: A potential carrier for selective delivery of antifibrotic drugs to rat and human hepatic stellate cells.

Beljaars L, Molema G, Weert B, Bonnema H, Olinga P, Groothuis GM, Meijer DK, Poelstra K.

Hepatology. 1999 May;29(5):1486-93.

PMID:
10216133
12.

Vesicular uptake system for the cation lucigenin in the rat hepatocyte.

Braakman I, Pijning T, Verest O, Weert B, Meijer DK, Groothuis GM.

Mol Pharmacol. 1989 Oct;36(4):537-42.

PMID:
2811856
13.

Carrier-mediated uptake of lucifer yellow in skate and rat hepatocytes: a fluid-phase marker revisited.

Ballatori N, Hager DN, Nundy S, Miller DS, Boyer JL.

Am J Physiol. 1999 Oct;277(4 Pt 1):G896-904.

14.

Massive and selective delivery of lipid-coated cationic lipoplexes of oligonucleotides targeted in vivo to hepatic endothelial cells.

Bartsch M, Weeke-Klimp AH, Meijer DK, Scherphof GL, Kamps JA.

Pharm Res. 2002 May;19(5):676-80.

PMID:
12069172
15.

The metabolic fate of the Anti-HIV active drug carrier succinylated human serum albumin after intravenous administration in rats.

Swart PJ, Kuipers ME, Smit C, Beljaars L, Ter Wiel J, Meijer DK.

J Drug Target. 2001 Apr;9(2):95-109.

PMID:
11697111
16.

Disease-induced drug targeting using novel peptide-ligand albumins.

Meijer DK, Beljaars L, Molema G, Poelstra K.

J Control Release. 2001 May 14;72(1-3):157-64.

PMID:
11389994
17.

Fluid phase endocytosis of [125I]iodixanol in rat liver parenchymal, endothelial and Kupffer cells.

Kjeken R, Mousavi SA, Brech A, Gjøen T, Berg T.

Cell Tissue Res. 2001 May;304(2):221-30.

PMID:
11396716
18.

Liver cell uptake and degradation of soluble immunoglobulin G immune complexes in vivo and in vitro in rats.

Johansson AG, Løvdal T, Magnusson KE, Berg T, Skogh T.

Hepatology. 1996 Jul;24(1):169-75.

PMID:
8707258
19.

Preparation and characterization of conjugates of (modified) human serum albumin and liposomes: drug carriers with an intrinsic anti-HIV activity.

Kamps JA, Swart PJ, Morselt HW, Pauwels R, De Béthune MP, De Clercq E, Meijer DK, Scherphof GL.

Biochim Biophys Acta. 1996 Jan 31;1278(2):183-90.

20.

Hepatic endocytosis of various types of mannose-terminated albumins. What is important, sugar recognition, net charge, or the combination of these features.

Jansen RW, Molema G, Ching TL, Oosting R, Harms G, Moolenaar F, Hardonk MJ, Meijer DK.

J Biol Chem. 1991 Feb 15;266(5):3343-8.

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