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Items: 1 to 20 of 168

1.

The fragile X mental retardation protein inhibits translation via interacting with mRNA.

Li Z, Zhang Y, Ku L, Wilkinson KD, Warren ST, Feng Y.

Nucleic Acids Res. 2001 Jun 1;29(11):2276-83.

2.

Evidence that fragile X mental retardation protein is a negative regulator of translation.

Laggerbauer B, Ostareck D, Keidel EM, Ostareck-Lederer A, Fischer U.

Hum Mol Genet. 2001 Feb 15;10(4):329-38.

3.

The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development.

Lu R, Wang H, Liang Z, Ku L, O'donnell WT, Li W, Warren ST, Feng Y.

Proc Natl Acad Sci U S A. 2004 Oct 19;101(42):15201-6. Epub 2004 Oct 8.

4.

The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif.

Schaeffer C, Bardoni B, Mandel JL, Ehresmann B, Ehresmann C, Moine H.

EMBO J. 2001 Sep 3;20(17):4803-13.

5.

The fragile X mental retardation protein and group I metabotropic glutamate receptors regulate levels of mRNA granules in brain.

Aschrafi A, Cunningham BA, Edelman GM, Vanderklish PW.

Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2180-5. Epub 2005 Jan 31.

6.

Purified recombinant Fmrp exhibits selective RNA binding as an intrinsic property of the fragile X mental retardation protein.

Brown V, Small K, Lakkis L, Feng Y, Gunter C, Wilkinson KD, Warren ST.

J Biol Chem. 1998 Jun 19;273(25):15521-7.

7.

New insights into fragile X syndrome: from molecules to neurobehaviors.

Jin P, Warren ST.

Trends Biochem Sci. 2003 Mar;28(3):152-8. Review.

PMID:
12633995
8.

Transport of fragile X mental retardation protein via granules in neurites of PC12 cells.

De Diego Otero Y, Severijnen LA, van Cappellen G, Schrier M, Oostra B, Willemsen R.

Mol Cell Biol. 2002 Dec;22(23):8332-41.

9.

The fragile X mental retardation protein FMRP binds elongation factor 1A mRNA and negatively regulates its translation in vivo.

Sung YJ, Dolzhanskaya N, Nolin SL, Brown T, Currie JR, Denman RB.

J Biol Chem. 2003 May 2;278(18):15669-78. Epub 2003 Feb 19.

10.

A novel function for fragile X mental retardation protein in translational activation.

Bechara EG, Didiot MC, Melko M, Davidovic L, Bensaid M, Martin P, Castets M, Pognonec P, Khandjian EW, Moine H, Bardoni B.

PLoS Biol. 2009 Jan 20;7(1):e16. doi: 10.1371/journal.pbio.1000016.

11.

The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses.

Zalfa F, Giorgi M, Primerano B, Moro A, Di Penta A, Reis S, Oostra B, Bagni C.

Cell. 2003 Feb 7;112(3):317-27.

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14.

The nuclear microspherule protein 58 is a novel RNA-binding protein that interacts with fragile X mental retardation protein in polyribosomal mRNPs from neurons.

Davidovic L, Bechara E, Gravel M, Jaglin XH, Tremblay S, Sik A, Bardoni B, Khandjian EW.

Hum Mol Genet. 2006 May 1;15(9):1525-38. Epub 2006 Mar 28.

15.

The fragile X mental retardation protein is associated with poly(A)+ mRNA in actively translating polyribosomes.

Corbin F, Bouillon M, Fortin A, Morin S, Rousseau F, Khandjian EW.

Hum Mol Genet. 1997 Sep;6(9):1465-72.

16.

A distinct FMRP polysomal population at an advanced stage of mammalian erythropoiesis.

Beaulieu MA.

Biochem Biophys Res Commun. 2000 Aug 28;275(2):608-10.

PMID:
10964711
17.

Analysis of the Fragile X mental retardation protein isoforms 1, 2 and 3 interactions with the G-quadruplex forming semaphorin 3F mRNA.

Evans TL, Blice-Baum AC, Mihailescu MR.

Mol Biosyst. 2012 Feb;8(2):642-9. doi: 10.1039/c1mb05322a. Epub 2011 Dec 1.

PMID:
22134704
18.

The RNA binding protein FMRP: new connections and missing links.

Schaeffer C, Beaulande M, Ehresmann C, Ehresmann B, Moine H.

Biol Cell. 2003 May-Jun;95(3-4):221-8. Review.

PMID:
12867085
19.

Developmentally-programmed FMRP expression in oligodendrocytes: a potential role of FMRP in regulating translation in oligodendroglia progenitors.

Wang H, Ku L, Osterhout DJ, Li W, Ahmadian A, Liang Z, Feng Y.

Hum Mol Genet. 2004 Jan 1;13(1):79-89. Epub 2003 Nov 12.

20.

FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association.

Feng Y, Absher D, Eberhart DE, Brown V, Malter HE, Warren ST.

Mol Cell. 1997 Dec;1(1):109-18.

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