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Items: 1 to 20 of 228

1.
2.

Streptozotocin-induced beta-cell death is independent of its inhibition of O-GlcNAcase in pancreatic Min6 cells.

Gao Y, Parker GJ, Hart GW.

Arch Biochem Biophys. 2000 Nov 15;383(2):296-302.

PMID:
11185566
3.

The role of O-linked protein glycosylation in beta-cell dysfunction.

Konrad RJ, Kudlow JE.

Int J Mol Med. 2002 Nov;10(5):535-9. Review.

PMID:
12373287
4.

Alloxan is an inhibitor of O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase.

Lee TN, Alborn WE, Knierman MD, Konrad RJ.

Biochem Biophys Res Commun. 2006 Dec 1;350(4):1038-43. Epub 2006 Oct 6.

PMID:
17045574
5.

Alloxan is an inhibitor of the enzyme O-linked N-acetylglucosamine transferase.

Konrad RJ, Zhang F, Hale JE, Knierman MD, Becker GW, Kudlow JE.

Biochem Biophys Res Commun. 2002 Apr 26;293(1):207-12.

PMID:
12054585
7.
8.

Glucose and streptozotocin stimulate p135 O-glycosylation in pancreatic islets.

Konrad RJ, Janowski KM, Kudlow JE.

Biochem Biophys Res Commun. 2000 Jan 7;267(1):26-32.

PMID:
10623569
9.

Streptozotocin inhibits O-GlcNAcase via the production of a transition state analog.

Toleman C, Paterson AJ, Shin R, Kudlow JE.

Biochem Biophys Res Commun. 2006 Feb 10;340(2):526-34. Epub 2005 Dec 19.

PMID:
16376298
10.

Streptozotocin, an analog of N-acetylglucosamine, blocks the removal of O-GlcNAc from intracellular proteins.

Roos MD, Xie W, Su K, Clark JA, Yang X, Chin E, Paterson AJ, Kudlow JE.

Proc Assoc Am Physicians. 1998 Sep-Oct;110(5):422-32.

PMID:
9756093
11.

Streptozotocin, an O-GlcNAcase inhibitor, blunts insulin and growth hormone secretion.

Liu K, Paterson AJ, Konrad RJ, Parlow AF, Jimi S, Roh M, Chin E Jr, Kudlow JE.

Mol Cell Endocrinol. 2002 Aug 30;194(1-2):135-46.

PMID:
12242036
13.

Cytosolic O-GlcNAc accumulation is not involved in beta-cell death in HIT-T15 or Min6.

Okuyama R, Yachi M.

Biochem Biophys Res Commun. 2001 Sep 21;287(2):366-71.

PMID:
11554736
14.
15.

Elevated O-linked N-acetylglucosamine metabolism in pancreatic beta-cells.

Hanover JA, Lai Z, Lee G, Lubas WA, Sato SM.

Arch Biochem Biophys. 1999 Feb 1;362(1):38-45.

PMID:
9917327
16.

Chemical dissection of the link between streptozotocin, O-GlcNAc, and pancreatic cell death.

Pathak S, Dorfmueller HC, Borodkin VS, van Aalten DM.

Chem Biol. 2008 Aug 25;15(8):799-807. doi: 10.1016/j.chembiol.2008.06.010.

17.

Structural insight into the mechanism of streptozotocin inhibition of O-GlcNAcase.

He Y, Martinez-Fleites C, Bubb A, Gloster TM, Davies GJ.

Carbohydr Res. 2009 Mar 31;344(5):627-31. doi: 10.1016/j.carres.2008.12.007. Epub 2008 Dec 13.

PMID:
19217614
18.
19.

O-GlcNAcase uses substrate-assisted catalysis: kinetic analysis and development of highly selective mechanism-inspired inhibitors.

Macauley MS, Whitworth GE, Debowski AW, Chin D, Vocadlo DJ.

J Biol Chem. 2005 Jul 8;280(27):25313-22. Epub 2005 Mar 28.

20.
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