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Results: 1 to 20 of 290

1.

Interactions of CCCH zinc finger proteins with mRNA: tristetraprolin-mediated AU-rich element-dependent mRNA degradation can occur in the absence of a poly(A) tail.

Lai WS, Blackshear PJ.

J Biol Chem. 2001 Jun 22;276(25):23144-54. Epub 2001 Mar 28.

PMID:
11279239
[PubMed - indexed for MEDLINE]
Free Article
2.

Interactions of CCCH zinc finger proteins with mRNA: non-binding tristetraprolin mutants exert an inhibitory effect on degradation of AU-rich element-containing mRNAs.

Lai WS, Kennington EA, Blackshear PJ.

J Biol Chem. 2002 Mar 15;277(11):9606-13. Epub 2002 Jan 8.

PMID:
11782475
[PubMed - indexed for MEDLINE]
Free Article
3.

Interactions of CCCH zinc finger proteins with mRNA. Binding of tristetraprolin-related zinc finger proteins to Au-rich elements and destabilization of mRNA.

Lai WS, Carballo E, Thorn JM, Kennington EA, Blackshear PJ.

J Biol Chem. 2000 Jun 9;275(23):17827-37.

PMID:
10751406
[PubMed - indexed for MEDLINE]
Free Article
4.

The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritis.

Carrick DM, Lai WS, Blackshear PJ.

Arthritis Res Ther. 2004;6(6):248-64. Epub 2004 Oct 8. Review.

PMID:
15535838
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Tristetraprolin and other CCCH tandem zinc-finger proteins in the regulation of mRNA turnover.

Blackshear PJ.

Biochem Soc Trans. 2002 Nov;30(Pt 6):945-52. Review.

PMID:
12440952
[PubMed - indexed for MEDLINE]
6.

Members of the tristetraprolin family of tandem CCCH zinc finger proteins exhibit CRM1-dependent nucleocytoplasmic shuttling.

Phillips RS, Ramos SB, Blackshear PJ.

J Biol Chem. 2002 Mar 29;277(13):11606-13. Epub 2002 Jan 16.

PMID:
11796723
[PubMed - indexed for MEDLINE]
Free Article
7.

Cellular mutants define a common mRNA degradation pathway targeting cytokine AU-rich elements.

Stoecklin G, Stoeckle P, Lu M, Muehlemann O, Moroni C.

RNA. 2001 Nov;7(11):1578-88.

PMID:
11720287
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Chorioallantoic fusion defects and embryonic lethality resulting from disruption of Zfp36L1, a gene encoding a CCCH tandem zinc finger protein of the Tristetraprolin family.

Stumpo DJ, Byrd NA, Phillips RS, Ghosh S, Maronpot RR, Castranio T, Meyers EN, Mishina Y, Blackshear PJ.

Mol Cell Biol. 2004 Jul;24(14):6445-55.

PMID:
15226444
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Polymorphisms in the genes encoding members of the tristetraprolin family of human tandem CCCH zinc finger proteins.

Blackshear PJ, Phillips RS, Vazquez-Matias J, Mohrenweiser H.

Prog Nucleic Acid Res Mol Biol. 2003;75:43-68.

PMID:
14604009
[PubMed - indexed for MEDLINE]
10.

Zfp36l3, a rodent X chromosome gene encoding a placenta-specific member of the Tristetraprolin family of CCCH tandem zinc finger proteins.

Blackshear PJ, Phillips RS, Ghosh S, Ramos SB, Richfield EK, Lai WS.

Biol Reprod. 2005 Aug;73(2):297-307. Epub 2005 Apr 6. Erratum in: Biol Reprod. 2005 Nov;73(5):1072. Ramos, Silvia V B [corrected to Ramos, Silvia B V].

PMID:
15814898
[PubMed - indexed for MEDLINE]
Free Article
11.

Roles of tumor necrosis factor-alpha receptor subtypes in the pathogenesis of the tristetraprolin-deficiency syndrome.

Carballo E, Blackshear PJ.

Blood. 2001 Oct 15;98(8):2389-95.

PMID:
11588035
[PubMed - indexed for MEDLINE]
Free Article
12.
13.

Influence of nonameric AU-rich tristetraprolin-binding sites on mRNA deadenylation and turnover.

Lai WS, Carrick DM, Blackshear PJ.

J Biol Chem. 2005 Oct 7;280(40):34365-77. Epub 2005 Aug 1.

PMID:
16061475
[PubMed - indexed for MEDLINE]
Free Article
14.

A novel mechanism of tumor suppression by destabilizing AU-rich growth factor mRNA.

Stoecklin G, Gross B, Ming XF, Moroni C.

Oncogene. 2003 Jun 5;22(23):3554-61.

PMID:
12789264
[PubMed - indexed for MEDLINE]
16.

Modulation of the fate of cytoplasmic mRNA by AU-rich elements: key sequence features controlling mRNA deadenylation and decay.

Xu N, Chen CY, Shyu AB.

Mol Cell Biol. 1997 Aug;17(8):4611-21.

PMID:
9234718
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Characteristics of the interaction of a synthetic human tristetraprolin tandem zinc finger peptide with AU-rich element-containing RNA substrates.

Blackshear PJ, Lai WS, Kennington EA, Brewer G, Wilson GM, Guan X, Zhou P.

J Biol Chem. 2003 May 30;278(22):19947-55. Epub 2003 Mar 14.

PMID:
12639954
[PubMed - indexed for MEDLINE]
Free Article
18.

Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin.

Carballo E, Lai WS, Blackshear PJ.

Science. 1998 Aug 14;281(5379):1001-5.

PMID:
9703499
[PubMed - indexed for MEDLINE]
Free Article
19.

Gene transduction of tristetraprolin or its active domain reduces TNF-alpha production by Jurkat T cells.

Suzuki E, Tsutsumi A, Goto D, Matsumoto I, Ito S, Otsu M, Onodera M, Takahashi S, Sato Y, Sumida T.

Int J Mol Med. 2006 May;17(5):801-9.

PMID:
16596264
[PubMed - indexed for MEDLINE]
20.

RNA sequence elements required for high affinity binding by the zinc finger domain of tristetraprolin: conformational changes coupled to the bipartite nature of Au-rich MRNA-destabilizing motifs.

Brewer BY, Malicka J, Blackshear PJ, Wilson GM.

J Biol Chem. 2004 Jul 2;279(27):27870-7. Epub 2004 Apr 26.

PMID:
15117938
[PubMed - indexed for MEDLINE]
Free Article

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