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Results: 1 to 20 of 414

1.

The human immunodeficiency virus type 1 Vpu protein inhibits NF-kappa B activation by interfering with beta TrCP-mediated degradation of Ikappa B.

Bour S, Perrin C, Akari H, Strebel K.

J Biol Chem. 2001 May 11;276(19):15920-8. Epub 2001 Feb 16.

PMID:
11278695
[PubMed - indexed for MEDLINE]
Free Article
2.
3.

A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif.

Margottin F, Bour SP, Durand H, Selig L, Benichou S, Richard V, Thomas D, Strebel K, Benarous R.

Mol Cell. 1998 Mar;1(4):565-74.

PMID:
9660940
[PubMed - indexed for MEDLINE]
Free Article
4.

Involvement of the betaTrCP in the ubiquitination and stability of the HIV-1 Vpu protein.

Belaïdouni N, Marchal C, Benarous R, Besnard-Guérin C.

Biochem Biophys Res Commun. 2007 Jun 8;357(3):688-93. Epub 2007 Apr 9.

PMID:
17445772
[PubMed - indexed for MEDLINE]
5.

Structural studies on 24P-IkappaBalpha peptide derived from a human IkappaB-alpha protein related to the inhibition of the activity of the transcription factor NF-kappaB.

Pons J, Evrard-Todeschi N, Bertho G, Gharbi-Benarous J, Sonois V, Benarous R, Girault JP.

Biochemistry. 2007 Mar 20;46(11):2958-72. Epub 2007 Feb 24.

PMID:
17319651
[PubMed - indexed for MEDLINE]
7.

Inhibition of β-TrcP-dependent ubiquitination of p53 by HIV-1 Vpu promotes p53-mediated apoptosis in human T cells.

Verma S, Ali A, Arora S, Banerjea AC.

Blood. 2011 Jun 16;117(24):6600-7. doi: 10.1182/blood-2011-01-333427. Epub 2011 Apr 26.

PMID:
21521785
[PubMed - indexed for MEDLINE]
Free Article
8.

SCF(beta-TRCP) and phosphorylation dependent ubiquitinationof I kappa B alpha catalyzed by Ubc3 and Ubc4.

Strack P, Caligiuri M, Pelletier M, Boisclair M, Theodoras A, Beer-Romero P, Glass S, Parsons T, Copeland RA, Auger KR, Benfield P, Brizuela L, Rolfe M.

Oncogene. 2000 Jul 20;19(31):3529-36.

PMID:
10918611
[PubMed - indexed for MEDLINE]
Free Article
9.

CD4 glycoprotein degradation induced by human immunodeficiency virus type 1 Vpu protein requires the function of proteasomes and the ubiquitin-conjugating pathway.

Schubert U, Antón LC, Bacík I, Cox JH, Bour S, Bennink JR, Orlowski M, Strebel K, Yewdell JW.

J Virol. 1998 Mar;72(3):2280-8.

PMID:
9499087
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Requirements for the selective degradation of CD4 receptor molecules by the human immunodeficiency virus type 1 Vpu protein in the endoplasmic reticulum.

Binette J, Dubé M, Mercier J, Halawani D, Latterich M, Cohen EA.

Retrovirology. 2007 Oct 15;4:75.

PMID:
17937819
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

HIV-1 Vpu sequesters beta-transducin repeat-containing protein (betaTrCP) in the cytoplasm and provokes the accumulation of beta-catenin and other SCFbetaTrCP substrates.

Besnard-Guerin C, Belaïdouni N, Lassot I, Segeral E, Jobart A, Marchal C, Benarous R.

J Biol Chem. 2004 Jan 2;279(1):788-95. Epub 2003 Oct 14.

PMID:
14561767
[PubMed - indexed for MEDLINE]
Free Article
12.

NMR studies of the phosphorylation motif of the HIV-1 protein Vpu bound to the F-box protein beta-TrCP.

Coadou G, Gharbi-Benarous J, Megy S, Bertho G, Evrard-Todeschi N, Segeral E, Benarous R, Girault JP.

Biochemistry. 2003 Dec 23;42(50):14741-51.

PMID:
14674748
[PubMed - indexed for MEDLINE]
13.

Inducible degradation of IkappaBalpha by the proteasome requires interaction with the F-box protein h-betaTrCP.

Kroll M, Margottin F, Kohl A, Renard P, Durand H, Concordet JP, Bachelerie F, Arenzana-Seisdedos F, Benarous R.

J Biol Chem. 1999 Mar 19;274(12):7941-5.

PMID:
10075690
[PubMed - indexed for MEDLINE]
Free Article
14.

Vpu antagonizes BST-2-mediated restriction of HIV-1 release via beta-TrCP and endo-lysosomal trafficking.

Mitchell RS, Katsura C, Skasko MA, Fitzpatrick K, Lau D, Ruiz A, Stephens EB, Margottin-Goguet F, Benarous R, Guatelli JC.

PLoS Pathog. 2009 May;5(5):e1000450. doi: 10.1371/journal.ppat.1000450. Epub 2009 May 29.

PMID:
19478868
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Regulated degradation of the HIV-1 Vpu protein through a betaTrCP-independent pathway limits the release of viral particles.

Estrabaud E, Le Rouzic E, Lopez-Vergès S, Morel M, Belaïdouni N, Benarous R, Transy C, Berlioz-Torrent C, Margottin-Goguet F.

PLoS Pathog. 2007 Jul 27;3(7):e104.

PMID:
17676996
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Induction of beta-transducin repeat-containing protein by JNK signaling and its role in the activation of NF-kappaB.

Spiegelman VS, Stavropoulos P, Latres E, Pagano M, Ronai Z, Slaga TJ, Fuchs SY.

J Biol Chem. 2001 Jul 20;276(29):27152-8. Epub 2001 May 24.

PMID:
11375388
[PubMed - indexed for MEDLINE]
Free Article
17.
18.

Activation of NF-kappa B/Rel by Tax involves degradation of I kappa B alpha and is blocked by a proteasome inhibitor.

Maggirwar SB, Harhaj E, Sun SC.

Oncogene. 1995 Sep 7;11(5):993-8.

PMID:
7675460
[PubMed - indexed for MEDLINE]
19.

NF-kappaB activation upon interaction of HIV-1 envelope glycoproteins with cell surface CD4 involves IkappaB kinases.

Bossis G, Salinas S, Cartier C, Devaux C, Briant L.

FEBS Lett. 2002 Apr 10;516(1-3):257-64.

PMID:
11959143
[PubMed - indexed for MEDLINE]
20.

All three IkappaB isoforms and most Rel family members are stably associated with the IkappaB kinase 1/2 complex.

Heilker R, Freuler F, Pulfer R, Di Padova F, Eder J.

Eur J Biochem. 1999 Jan;259(1-2):253-61.

PMID:
9914500
[PubMed - indexed for MEDLINE]
Free Article
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