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Similar articles for PubMed (Select 11278042)

1.

Synthesis and influenza virus sialidase inhibitory activity of analogues of 4-Guanidino-Neu5Ac2en (Zanamivir) modified in the glycerol side-chain.

Andrews DM, Cherry PC, Humber DC, Jones PS, Keeling SP, Martin PF, Shaw CD, Swanson S.

Eur J Med Chem. 1999 Jul-Aug;34(7-8):563-74.

PMID:
11278042
2.

Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 1. Discovery, synthesis, biological activity, and structure-activity relationships of 4-guanidino- and 4-amino-4H-pyran-6-carboxamides.

Smith PW, Sollis SL, Howes PD, Cherry PC, Starkey ID, Cobley KN, Weston H, Scicinski J, Merritt A, Whittington A, Wyatt P, Taylor N, Green D, Bethell R, Madar S, Fenton RJ, Morley PJ, Pateman T, Beresford A.

J Med Chem. 1998 Mar 12;41(6):787-97.

PMID:
9526555
3.

4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid is a highly effective inhibitor both of the sialidase (neuraminidase) and of growth of a wide range of influenza A and B viruses in vitro.

Woods JM, Bethell RC, Coates JA, Healy N, Hiscox SA, Pearson BA, Ryan DM, Ticehurst J, Tilling J, Walcott SM, et al.

Antimicrob Agents Chemother. 1993 Jul;37(7):1473-9.

4.

Sialidase inhibitors related to zanamivir. Further SAR studies of 4-amino-4H-pyran-2-carboxylic acid-6-propylamides.

Wyatt PG, Coomber BA, Evans DN, Jack TI, Fulton HE, Wonacott AJ, Colman P, Varghese J.

Bioorg Med Chem Lett. 2001 Mar 12;11(5):669-73.

PMID:
11266166
6.

Synthesis and anti-influenza virus activity of 4-guanidino-7-substituted Neu5Ac2en derivatives.

Honda T, Masuda T, Yoshida S, Arai M, Kobayashi Y, Yamashita M.

Bioorg Med Chem Lett. 2002 Aug 5;12(15):1921-4.

PMID:
12113809
7.

Synthesis and anti-influenza evaluation of polyvalent sialidase inhibitors bearing 4-guanidino-Neu5Ac2en derivatives.

Honda T, Yoshida S, Arai M, Masuda T, Yamashita M.

Bioorg Med Chem Lett. 2002 Aug 5;12(15):1929-32.

PMID:
12113811
8.

Synthesis and anti-influenza evaluation of polyvalent sialidase inhibitors bearing 4-guanidino-Neu5Ac2en derivatives.

Masuda T, Yoshida S, Arai M, Kaneko S, Yamashita M, Honda T.

Chem Pharm Bull (Tokyo). 2003 Dec;51(12):1386-98.

9.

Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4-amino-4H-pyran-6-carboxamides and sialidase from influenza virus types A and B.

Taylor NR, Cleasby A, Singh O, Skarzynski T, Wonacott AJ, Smith PW, Sollis SL, Howes PD, Cherry PC, Bethell R, Colman P, Varghese J.

J Med Chem. 1998 Mar 12;41(6):798-807.

PMID:
9526556
10.

Molecular basis for the resistance of influenza viruses to 4-guanidino-Neu5Ac2en.

Staschke KA, Colacino JM, Baxter AJ, Air GM, Bansal A, Hornback WJ, Munroe JE, Laver WG.

Virology. 1995 Dec 20;214(2):642-6.

11.

Zanamivir. A potent and selective inhibitor of influenza A and B viruses.

Aoki FY, Hayden FG.

Clin Pharmacokinet. 1999;36 Suppl 1:v-ix. Review. No abstract available.

PMID:
10429834
12.

Generation and characterization of an influenza virus neuraminidase variant with decreased sensitivity to the neuraminidase-specific inhibitor 4-guanidino-Neu5Ac2en.

Blick TJ, Tiong T, Sahasrabudhe A, Varghese JN, Colman PM, Hart GJ, Bethell RC, McKimm-Breschkin JL.

Virology. 1995 Dec 20;214(2):475-84.

13.

Synthesis and anti-influenza virus activity of 7-O-alkylated derivatives related to zanamivir.

Honda T, Masuda T, Yoshida S, Arai M, Kaneko S, Yamashita M.

Bioorg Med Chem Lett. 2002 Aug 5;12(15):1925-8.

PMID:
12113810
14.

Generation and characterization of variants of NWS/G70C influenza virus after in vitro passage in 4-amino-Neu5Ac2en and 4-guanidino-Neu5Ac2en.

McKimm-Breschkin JL, Blick TJ, Sahasrabudhe A, Tiong T, Marshall D, Hart GJ, Bethell RC, Penn CR.

Antimicrob Agents Chemother. 1996 Jan;40(1):40-6.

15.

Sialidase inhibitors related to zanamivir: synthesis and biological evaluation of 4H-pyran 6-ether and ketone.

Smith PW, Robinson JE, Evans DN, Sollis SL, Howes PD, Trivedi N, Bethell RC.

Bioorg Med Chem Lett. 1999 Feb 22;9(4):601-4.

PMID:
10098672
18.

Carbocyclic influenza neuraminidase inhibitors possessing a C3-cyclic amine side chain: synthesis and inhibitory activity.

Lew W, Wu H, Chen X, Graves BJ, Escarpe PA, MacArthur HL, Mendel DB, Kim CU.

Bioorg Med Chem Lett. 2000 Jun 5;10(11):1257-60.

PMID:
10866394
19.

Selection of influenza A and B viruses for resistance to 4-guanidino-Neu5Ac2en in cell culture.

Colacino JM, Laver WG, Air GM.

J Infect Dis. 1997 Aug;176 Suppl 1:S66-8.

20.

Structure-based inhibitors of influenza virus sialidase. A benzoic acid lead with novel interaction.

Singh S, Jedrzejas MJ, Air GM, Luo M, Laver WG, Brouillette WJ.

J Med Chem. 1995 Aug 18;38(17):3217-25.

PMID:
7650674
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