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Results: 1 to 20 of 101

1.

Tpl-2 induces apoptosis by promoting the assembly of protein complexes that contain caspase-9, the adapter protein Tvl-1, and procaspase-3.

Patriotis C, Russeva MG, Lin JH, Srinivasula SM, Markova DZ, Tsatsanis C, Makris A, Alnemri ES, Tsichlis PN.

J Cell Physiol. 2001 May;187(2):176-87.

PMID:
11267997
[PubMed - indexed for MEDLINE]
2.

Apoptosis-associated speck-like protein containing a caspase recruitment domain is a regulator of procaspase-1 activation.

Stehlik C, Lee SH, Dorfleutner A, Stassinopoulos A, Sagara J, Reed JC.

J Immunol. 2003 Dec 1;171(11):6154-63.

PMID:
14634131
[PubMed - indexed for MEDLINE]
Free Article
3.

Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis.

Hu Y, Benedict MA, Ding L, Núñez G.

EMBO J. 1999 Jul 1;18(13):3586-95.

PMID:
10393175
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90.

Pandey P, Saleh A, Nakazawa A, Kumar S, Srinivasula SM, Kumar V, Weichselbaum R, Nalin C, Alnemri ES, Kufe D, Kharbanda S.

EMBO J. 2000 Aug 15;19(16):4310-22.

PMID:
10944114
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Expression and functional analysis of Apaf-1 isoforms. Extra Wd-40 repeat is required for cytochrome c binding and regulated activation of procaspase-9.

Benedict MA, Hu Y, Inohara N, Núñez G.

J Biol Chem. 2000 Mar 24;275(12):8461-8.

PMID:
10722681
[PubMed - indexed for MEDLINE]
Free Article
7.

TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer.

Pathan N, Marusawa H, Krajewska M, Matsuzawa S, Kim H, Okada K, Torii S, Kitada S, Krajewski S, Welsh K, Pio F, Godzik A, Reed JC.

J Biol Chem. 2001 Aug 24;276(34):32220-9. Epub 2001 Jun 14.

PMID:
11408476
[PubMed - indexed for MEDLINE]
Free Article
8.

Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1.

Chau BN, Cheng EH, Kerr DA, Hardwick JM.

Mol Cell. 2000 Jul;6(1):31-40.

PMID:
10949025
[PubMed - indexed for MEDLINE]
Free Article
9.

Cloning of a novel Apaf-1-interacting protein: a potent suppressor of apoptosis and ischemic neuronal cell death.

Cao G, Xiao M, Sun F, Xiao X, Pei W, Li J, Graham SH, Simon RP, Chen J.

J Neurosci. 2004 Jul 7;24(27):6189-201.

PMID:
15240811
[PubMed - indexed for MEDLINE]
Free Article
10.

Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1.

Poyet JL, Srinivasula SM, Tnani M, Razmara M, Fernandes-Alnemri T, Alnemri ES.

J Biol Chem. 2001 Jul 27;276(30):28309-13. Epub 2001 Jun 4.

PMID:
11390368
[PubMed - indexed for MEDLINE]
Free Article
11.

XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis.

Bratton SB, Lewis J, Butterworth M, Duckett CS, Cohen GM.

Cell Death Differ. 2002 Sep;9(9):881-92.

PMID:
12181739
[PubMed - indexed for MEDLINE]
Free Article
12.

The role of Apaf-1, caspase-9, and bid proteins in etoposide- or paclitaxel-induced mitochondrial events during apoptosis.

Perkins CL, Fang G, Kim CN, Bhalla KN.

Cancer Res. 2000 Mar 15;60(6):1645-53.

PMID:
10749135
[PubMed - indexed for MEDLINE]
Free Article
13.

Increased expression of Apaf-1 and procaspase-3 and the functionality of intrinsic apoptosis apparatus in non-small cell lung carcinoma.

Krepela E, Procházka J, Liul X, Fiala P, Kinkor Z.

Biol Chem. 2004 Feb;385(2):153-68.

PMID:
15101558
[PubMed - indexed for MEDLINE]
14.

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9.

Zou H, Li Y, Liu X, Wang X.

J Biol Chem. 1999 Apr 23;274(17):11549-56.

PMID:
10206961
[PubMed - indexed for MEDLINE]
Free Article
15.

Bcl-xES, a BH4- and BH2-containing antiapoptotic protein, delays Bax oligomer formation and binds Apaf-1, blocking procaspase-9 activation.

Schmitt E, Paquet C, Beauchemin M, Bertrand R.

Oncogene. 2004 May 13;23(22):3915-31.

PMID:
15048082
[PubMed - indexed for MEDLINE]
16.

dFADD, a novel death domain-containing adapter protein for the Drosophila caspase DREDD.

Hu S, Yang X.

J Biol Chem. 2000 Oct 6;275(40):30761-4.

PMID:
10934188
[PubMed - indexed for MEDLINE]
Free Article
17.

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome.

Beere HM, Wolf BB, Cain K, Mosser DD, Mahboubi A, Kuwana T, Tailor P, Morimoto RI, Cohen GM, Green DR.

Nat Cell Biol. 2000 Aug;2(8):469-75.

PMID:
10934466
[PubMed - indexed for MEDLINE]
18.

Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1.

Qin H, Srinivasula SM, Wu G, Fernandes-Alnemri T, Alnemri ES, Shi Y.

Nature. 1999 Jun 10;399(6736):549-57.

PMID:
10376594
[PubMed - indexed for MEDLINE]
19.

Execution of macrophage apoptosis by Mycobacterium avium through apoptosis signal-regulating kinase 1/p38 mitogen-activated protein kinase signaling and caspase 8 activation.

Bhattacharyya A, Pathak S, Basak C, Law S, Kundu M, Basu J.

J Biol Chem. 2003 Jul 18;278(29):26517-25. Epub 2003 Apr 30.

PMID:
12724324
[PubMed - indexed for MEDLINE]
Free Article
20.

Bile acids stimulate cFLIP phosphorylation enhancing TRAIL-mediated apoptosis.

Higuchi H, Yoon JH, Grambihler A, Werneburg N, Bronk SF, Gores GJ.

J Biol Chem. 2003 Jan 3;278(1):454-61. Epub 2002 Oct 28.

PMID:
12407100
[PubMed - indexed for MEDLINE]
Free Article

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