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Results: 1 to 20 of 747

1.

Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

Kawarabayashi T, Younkin LH, Saido TC, Shoji M, Ashe KH, Younkin SG.

J Neurosci. 2001 Jan 15;21(2):372-81.

PMID:
11160418
[PubMed - indexed for MEDLINE]
Free Article
2.

Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease.

Kawarabayashi T, Shoji M, Younkin LH, Wen-Lang L, Dickson DW, Murakami T, Matsubara E, Abe K, Ashe KH, Younkin SG.

J Neurosci. 2004 Apr 14;24(15):3801-9.

PMID:
15084661
[PubMed - indexed for MEDLINE]
Free Article
3.

Transthyretin accelerates vascular Abeta deposition in a mouse model of Alzheimer's disease.

Wati H, Kawarabayashi T, Matsubara E, Kasai A, Hirasawa T, Kubota T, Harigaya Y, Shoji M, Maeda S.

Brain Pathol. 2009 Jan;19(1):48-57. doi: 10.1111/j.1750-3639.2008.00166.x. Epub 2008 Apr 22.

PMID:
18429966
[PubMed - indexed for MEDLINE]
4.

Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.

Fryer JD, Simmons K, Parsadanian M, Bales KR, Paul SM, Sullivan PM, Holtzman DM.

J Neurosci. 2005 Mar 16;25(11):2803-10.

PMID:
15772340
[PubMed - indexed for MEDLINE]
Free Article
5.

In vivo assessment of brain interstitial fluid with microdialysis reveals plaque-associated changes in amyloid-beta metabolism and half-life.

Cirrito JR, May PC, O'Dell MA, Taylor JW, Parsadanian M, Cramer JW, Audia JE, Nissen JS, Bales KR, Paul SM, DeMattos RB, Holtzman DM.

J Neurosci. 2003 Oct 1;23(26):8844-53.

PMID:
14523085
[PubMed - indexed for MEDLINE]
Free Article
6.

Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis.

Praticò D, Uryu K, Leight S, Trojanoswki JQ, Lee VM.

J Neurosci. 2001 Jun 15;21(12):4183-7.

PMID:
11404403
[PubMed - indexed for MEDLINE]
Free Article
7.

beta-amyloid deposits in transgenic mice expressing human beta-amyloid precursor protein have the same characteristics as those in Alzheimer's disease.

Terai K, Iwai A, Kawabata S, Tasaki Y, Watanabe T, Miyata K, Yamaguchi T.

Neuroscience. 2001;104(2):299-310.

PMID:
11377835
[PubMed - indexed for MEDLINE]
8.

Dynamics of {beta}-amyloid reductions in brain, cerebrospinal fluid, and plasma of {beta}-amyloid precursor protein transgenic mice treated with a {gamma}-secretase inhibitor.

Barten DM, Guss VL, Corsa JA, Loo A, Hansel SB, Zheng M, Munoz B, Srinivasan K, Wang B, Robertson BJ, Polson CT, Wang J, Roberts SB, Hendrick JP, Anderson JJ, Loy JK, Denton R, Verdoorn TA, Smith DW, Felsenstein KM.

J Pharmacol Exp Ther. 2005 Feb;312(2):635-43. Epub 2004 Sep 27.

PMID:
15452193
[PubMed - indexed for MEDLINE]
Free Article
9.

Cholinergic neuropathology in a mouse model of Alzheimer's disease.

German DC, Yazdani U, Speciale SG, Pasbakhsh P, Games D, Liang CL.

J Comp Neurol. 2003 Aug 4;462(4):371-81.

PMID:
12811807
[PubMed - indexed for MEDLINE]
10.

Deposition of mouse amyloid beta in human APP/PS1 double and single AD model transgenic mice.

van Groen T, Kiliaan AJ, Kadish I.

Neurobiol Dis. 2006 Sep;23(3):653-62. Epub 2006 Jul 10.

PMID:
16829076
[PubMed - indexed for MEDLINE]
11.

Vascular endothelial growth factor (VEGF) affects processing of amyloid precursor protein and beta-amyloidogenesis in brain slice cultures derived from transgenic Tg2576 mouse brain.

Bürger S, Noack M, Kirazov LP, Kirazov EP, Naydenov CL, Kouznetsova E, Yafai Y, Schliebs R.

Int J Dev Neurosci. 2009 Oct;27(6):517-23. doi: 10.1016/j.ijdevneu.2009.06.011. Epub 2009 Jul 7.

PMID:
19589380
[PubMed - indexed for MEDLINE]
12.

The evolution of A beta peptide burden in the APP23 transgenic mice: implications for A beta deposition in Alzheimer disease.

Kuo YM, Beach TG, Sue LI, Scott S, Layne KJ, Kokjohn TA, Kalback WM, Luehrs DC, Vishnivetskaya TA, Abramowski D, Sturchler-Pierrat C, Staufenbiel M, Weller RO, Roher AE.

Mol Med. 2001 Sep;7(9):609-18.

PMID:
11778650
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Reduced effectiveness of Abeta1-42 immunization in APP transgenic mice with significant amyloid deposition.

Das P, Murphy MP, Younkin LH, Younkin SG, Golde TE.

Neurobiol Aging. 2001 Sep-Oct;22(5):721-7.

PMID:
11705631
[PubMed - indexed for MEDLINE]
14.

High sensitivity analysis of amyloid-beta peptide composition in amyloid deposits from human and PS2APP mouse brain.

Güntert A, Döbeli H, Bohrmann B.

Neuroscience. 2006 Dec 1;143(2):461-75. Epub 2006 Sep 27.

PMID:
17008022
[PubMed - indexed for MEDLINE]
15.

Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer's disease.

Dutescu RM, Li QX, Crowston J, Masters CL, Baird PN, Culvenor JG.

Graefes Arch Clin Exp Ophthalmol. 2009 Sep;247(9):1213-21. doi: 10.1007/s00417-009-1060-3. Epub 2009 Mar 7.

PMID:
19271231
[PubMed - indexed for MEDLINE]
16.

A transgenic rat that develops Alzheimer's disease-like amyloid pathology, deficits in synaptic plasticity and cognitive impairment.

Liu L, Orozco IJ, Planel E, Wen Y, Bretteville A, Krishnamurthy P, Wang L, Herman M, Figueroa H, Yu WH, Arancio O, Duff K.

Neurobiol Dis. 2008 Jul;31(1):46-57. doi: 10.1016/j.nbd.2008.03.005. Epub 2008 Apr 7.

PMID:
18504134
[PubMed - indexed for MEDLINE]
17.

Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease.

DeMattos RB, Bales KR, Parsadanian M, O'Dell MA, Foss EM, Paul SM, Holtzman DM.

J Neurochem. 2002 Apr;81(2):229-36.

PMID:
12064470
[PubMed - indexed for MEDLINE]
18.

Progranulin expression correlates with dense-core amyloid plaque burden in Alzheimer disease mouse models.

Pereson S, Wils H, Kleinberger G, McGowan E, Vandewoestyne M, Van Broeck B, Joris G, Cuijt I, Deforce D, Hutton M, Van Broeckhoven C, Kumar-Singh S.

J Pathol. 2009 Oct;219(2):173-81. doi: 10.1002/path.2580.

PMID:
19557827
[PubMed - indexed for MEDLINE]
19.

A highly insoluble state of Abeta similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice.

Philipson O, Hammarström P, Nilsson KP, Portelius E, Olofsson T, Ingelsson M, Hyman BT, Blennow K, Lannfelt L, Kalimo H, Nilsson LN.

Neurobiol Aging. 2009 Sep;30(9):1393-405. doi: 10.1016/j.neurobiolaging.2007.11.022. Epub 2008 Jan 14.

PMID:
18192084
[PubMed - indexed for MEDLINE]
20.

A transgenic rat model of Alzheimer's disease with extracellular Abeta deposition.

Flood DG, Lin YG, Lang DM, Trusko SP, Hirsch JD, Savage MJ, Scott RW, Howland DS.

Neurobiol Aging. 2009 Jul;30(7):1078-90. Epub 2007 Nov 28.

PMID:
18053619
[PubMed - indexed for MEDLINE]

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