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Results: 1 to 20 of 186

1.

Growth factor-stimulated phosphorylation of Akt and p70(S6K) is differentially inhibited by LY294002 and Wortmannin.

Adi S, Wu NY, Rosenthal SM.

Endocrinology. 2001 Jan;142(1):498-501.

PMID:
11145615
[PubMed - indexed for MEDLINE]
2.

Temporal activation of p70 S6 kinase and Akt1 by insulin: PI 3-kinase-dependent and -independent mechanisms.

Somwar R, Sumitani S, Taha C, Sweeney G, Klip A.

Am J Physiol. 1998 Oct;275(4 Pt 1):E618-25.

PMID:
9755080
[PubMed - indexed for MEDLINE]
Free Article
3.

Phosphatidylinositol 3-kinase (PI-3K)/Akt but not PI-3K/p70 S6 kinase signaling mediates IGF-1-promoted lens epithelial cell survival.

Chandrasekher G, Sailaja D.

Invest Ophthalmol Vis Sci. 2004 Oct;45(10):3577-88.

PMID:
15452065
[PubMed - indexed for MEDLINE]
Free Article
4.

Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways.

Thimmaiah KN, Easton J, Huang S, Veverka KA, Germain GS, Harwood FC, Houghton PJ.

Cancer Res. 2003 Jan 15;63(2):364-74.

PMID:
12543789
[PubMed - indexed for MEDLINE]
Free Article
5.

Insulin-induced Drosophila S6 kinase activation requires phosphoinositide 3-kinase and protein kinase B.

Lizcano JM, Alrubaie S, Kieloch A, Deak M, Leevers SJ, Alessi DR.

Biochem J. 2003 Sep 1;374(Pt 2):297-306.

PMID:
12841848
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Signal pathways involved in activation of p70S6K and phosphorylation of 4E-BP1 following exposure of multiple myeloma tumor cells to interleukin-6.

Shi Y, Hsu JH, Hu L, Gera J, Lichtenstein A.

J Biol Chem. 2002 May 3;277(18):15712-20. Epub 2002 Feb 28.

PMID:
11872747
[PubMed - indexed for MEDLINE]
Free Article
9.

Intracellular signaling of angiotensin II-induced p70 S6 kinase phosphorylation at Ser(411) in vascular smooth muscle cells. Possible requirement of epidermal growth factor receptor, Ras, extracellular signal-regulated kinase, and Akt.

Eguchi S, Iwasaki H, Ueno H, Frank GD, Motley ED, Eguchi K, Marumo F, Hirata Y, Inagami T.

J Biol Chem. 1999 Dec 24;274(52):36843-51.

PMID:
10601235
[PubMed - indexed for MEDLINE]
Free Article
10.

Differential regulation by calcium reveals distinct signaling requirements for the activation of Akt and p70S6k.

Conus NM, Hemmings BA, Pearson RB.

J Biol Chem. 1998 Feb 20;273(8):4776-82.

PMID:
9468542
[PubMed - indexed for MEDLINE]
Free Article
11.

The lethal effects of pharmacological cyclin-dependent kinase inhibitors in human leukemia cells proceed through a phosphatidylinositol 3-kinase/Akt-dependent process.

Yu C, Rahmani M, Dai Y, Conrad D, Krystal G, Dent P, Grant S.

Cancer Res. 2003 Apr 15;63(8):1822-33.

PMID:
12702569
[PubMed - indexed for MEDLINE]
Free Article
12.

Regulation of the phosphatidylinositol 3-kinase, Akt/protein kinase B, FRAP/mammalian target of rapamycin, and ribosomal S6 kinase 1 signaling pathways by thyroid-stimulating hormone (TSH) and stimulating type TSH receptor antibodies in the thyroid gland.

Suh JM, Song JH, Kim DW, Kim H, Chung HK, Hwang JH, Kim JM, Hwang ES, Chung J, Han JH, Cho BY, Ro HK, Shong M.

J Biol Chem. 2003 Jun 13;278(24):21960-71. Epub 2003 Mar 30.

PMID:
12668683
[PubMed - indexed for MEDLINE]
Free Article
13.

Hydrogen peroxide generated during cellular insulin stimulation is integral to activation of the distal insulin signaling cascade in 3T3-L1 adipocytes.

Mahadev K, Wu X, Zilbering A, Zhu L, Lawrence JT, Goldstein BJ.

J Biol Chem. 2001 Dec 28;276(52):48662-9. Epub 2001 Oct 11.

PMID:
11598110
[PubMed - indexed for MEDLINE]
Free Article
14.
15.

Regulation of neuronal survival by the serine-threonine protein kinase Akt.

Dudek H, Datta SR, Franke TF, Birnbaum MJ, Yao R, Cooper GM, Segal RA, Kaplan DR, Greenberg ME.

Science. 1997 Jan 31;275(5300):661-5.

PMID:
9005851
[PubMed - indexed for MEDLINE]
Free Article
16.
17.

Dichloroacetate stimulates glycogen accumulation in primary hepatocytes through an insulin-independent mechanism.

Lingohr MK, Bull RJ, Kato-Weinstein J, Thrall BD.

Toxicol Sci. 2002 Aug;68(2):508-15.

PMID:
12151648
[PubMed - indexed for MEDLINE]
Free Article
18.

Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma.

Pene F, Claessens YE, Muller O, ViguiƩ F, Mayeux P, Dreyfus F, Lacombe C, Bouscary D.

Oncogene. 2002 Sep 26;21(43):6587-97.

PMID:
12242656
[PubMed - indexed for MEDLINE]
Free Article
19.

Interleukin-18 is a pro-hypertrophic cytokine that acts through a phosphatidylinositol 3-kinase-phosphoinositide-dependent kinase-1-Akt-GATA4 signaling pathway in cardiomyocytes.

Chandrasekar B, Mummidi S, Claycomb WC, Mestril R, Nemer M.

J Biol Chem. 2005 Feb 11;280(6):4553-67. Epub 2004 Dec 1.

PMID:
15574430
[PubMed - indexed for MEDLINE]
Free Article
20.

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