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Items: 1 to 20 of 108


ERK5 and ERK2 cooperate to regulate NF-kappaB and cell transformation.

Pearson G, English JM, White MA, Cobb MH.

J Biol Chem. 2001 Mar 16;276(11):7927-31. Epub 2000 Dec 15.


Contribution of the ERK5/MEK5 pathway to Ras/Raf signaling and growth control.

English JM, Pearson G, Hockenberry T, Shivakumar L, White MA, Cobb MH.

J Biol Chem. 1999 Oct 29;274(44):31588-92.


Rit, a non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways.

Rusyn EV, Reynolds ER, Shao H, Grana TM, Chan TO, Andres DA, Cox AD.

Oncogene. 2000 Sep 28;19(41):4685-94.


Characterization of the MEK5-ERK5 module in human neutrophils and its relationship to ERK1/ERK2 in the chemotactic response.

Hii CS, Anson DS, Costabile M, Mukaro V, Dunning K, Ferrante A.

J Biol Chem. 2004 Nov 26;279(48):49825-34. Epub 2004 Sep 20.


MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway.

Sun W, Kesavan K, Schaefer BC, Garrington TP, Ware M, Johnson NL, Gelfand EW, Johnson GL.

J Biol Chem. 2001 Feb 16;276(7):5093-100. Epub 2000 Nov 9.


Regulation of c-Fos and Fra-1 by the MEK5-ERK5 pathway.

Terasawa K, Okazaki K, Nishida E.

Genes Cells. 2003 Mar;8(3):263-73.


Activation of either ERK1/2 or ERK5 MAP kinase pathways can lead to disruption of the actin cytoskeleton.

Barros JC, Marshall CJ.

J Cell Sci. 2005 Apr 15;118(Pt 8):1663-71. Epub 2005 Mar 29.


Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism.

Hoyle PE, Moye PW, Steelman LS, Blalock WL, Franklin RA, Pearce M, Cherwinski H, Bosch E, McMahon M, McCubrey JA.

Leukemia. 2000 Apr;14(4):642-56.


PB1 domains of MEKK2 and MEKK3 interact with the MEK5 PB1 domain for activation of the ERK5 pathway.

Nakamura K, Johnson GL.

J Biol Chem. 2003 Sep 26;278(39):36989-92. Epub 2003 Aug 11.


Regulation of epidermal growth factor-induced connexin 43 gap junction communication by big mitogen-activated protein kinase1/ERK5 but not ERK1/2 kinase activation.

Cameron SJ, Malik S, Akaike M, Lerner-Marmarosh N, Yan C, Lee JD, Abe J, Yang J.

J Biol Chem. 2003 May 16;278(20):18682-8. Epub 2003 Mar 12.


Role of Ras in metal-induced EGF receptor signaling and NF-kappaB activation in human airway epithelial cells.

Wu W, Jaspers I, Zhang W, Graves LM, Samet JM.

Am J Physiol Lung Cell Mol Physiol. 2002 May;282(5):L1040-8.


Signalling events involved in interferon-gamma-inducible macrophage nitric oxide generation.

Blanchette J, Jaramillo M, Olivier M.

Immunology. 2003 Apr;108(4):513-22.


A novel mitogen-activated protein kinase is responsive to Raf and mediates growth factor specificity.

Janulis M, Trakul N, Greene G, Schaefer EM, Lee JD, Rosner MR.

Mol Cell Biol. 2001 Mar;21(6):2235-47.


Uncoupling Raf1 from MEK1/2 impairs only a subset of cellular responses to Raf activation.

Pearson G, Bumeister R, Henry DO, Cobb MH, White MA.

J Biol Chem. 2000 Dec 1;275(48):37303-6.

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