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Vasodilator-stimulated phosphoprotein serine 239 phosphorylation as a sensitive monitor of defective nitric oxide/cGMP signaling and endothelial dysfunction.

Oelze M, Mollnau H, Hoffmann N, Warnholtz A, Bodenschatz M, Smolenski A, Walter U, Skatchkov M, Meinertz T, Münzel T.

Circ Res. 2000 Nov 24;87(11):999-1005.


Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling.

Mollnau H, Wendt M, Szöcs K, Lassègue B, Schulz E, Oelze M, Li H, Bodenschatz M, August M, Kleschyov AL, Tsilimingas N, Walter U, Förstermann U, Meinertz T, Griendling K, Münzel T.

Circ Res. 2002 Mar 8;90(4):E58-65.


Effects of in vivo nitroglycerin treatment on activity and expression of the guanylyl cyclase and cGMP-dependent protein kinase and their downstream target vasodilator-stimulated phosphoprotein in aorta.

Mülsch A, Oelze M, Klöss S, Mollnau H, Töpfer A, Smolenski A, Walter U, Stasch JP, Warnholtz A, Hink U, Meinertz T, Münzel T.

Circulation. 2001 May 1;103(17):2188-94.


Nebivolol prevents vascular NOS III uncoupling in experimental hyperlipidemia and inhibits NADPH oxidase activity in inflammatory cells.

Mollnau H, Schulz E, Daiber A, Baldus S, Oelze M, August M, Wendt M, Walter U, Geiger C, Agrawal R, Kleschyov AL, Meinertz T, Münzel T.

Arterioscler Thromb Vasc Biol. 2003 Apr 1;23(4):615-21. Epub 2003 Mar 6.


Adverse effects of nitroglycerin treatment on endothelial function, vascular nitrotyrosine levels and cGMP-dependent protein kinase activity in hyperlipidemic Watanabe rabbits.

Warnholtz A, Mollnau H, Heitzer T, Kontush A, Möller-Bertram T, Lavall D, Giaid A, Beisiegel U, Marklund SL, Walter U, Meinertz T, Munzel T.

J Am Coll Cardiol. 2002 Oct 2;40(7):1356-63.


Functional and biochemical analysis of endothelial (dys)function and NO/cGMP signaling in human blood vessels with and without nitroglycerin pretreatment.

Schulz E, Tsilimingas N, Rinze R, Reiter B, Wendt M, Oelze M, Woelken-Weckmüller S, Walter U, Reichenspurner H, Meinertz T, Münzel T.

Circulation. 2002 Mar 12;105(10):1170-5.


Restoration of impaired endothelium-dependent coronary vasodilation in failing heart: role of eNOS phosphorylation and CGMP/cGK-I signaling.

Gill RM, Braz JC, Jin N, Etgen GJ, Shen W.

Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H2782-90. Epub 2007 Feb 23.


Endothelium-dependent and -independent relaxation and VASP serines 157/239 phosphorylation by cyclic nucleotide-elevating vasodilators in rat aorta.

Schäfer A, Burkhardt M, Vollkommer T, Bauersachs J, Münzel T, Walter U, Smolenski A.

Biochem Pharmacol. 2003 Feb 1;65(3):397-405.


Regulation of human endothelial cell focal adhesion sites and migration by cGMP-dependent protein kinase I.

Smolenski A, Poller W, Walter U, Lohmann SM.

J Biol Chem. 2000 Aug 18;275(33):25723-32.


Does nitric oxide mediate the vasodilator activity of nitroglycerin?

Kleschyov AL, Oelze M, Daiber A, Huang Y, Mollnau H, Schulz E, Sydow K, Fichtlscherer B, Mülsch A, Münzel T.

Circ Res. 2003 Oct 31;93(9):e104-12. Epub 2003 Oct 9.


Phosphorylation of vasodilator-stimulated phosphoprotein: a consequence of nitric oxide- and cGMP-mediated signal transduction in brain capillary endothelial cells and astrocytes.

Sporbert A, Mertsch K, Smolenski A, Haseloff RF, Schönfelder G, Paul M, Ruth P, Walter U, Blasig IE.

Brain Res Mol Brain Res. 1999 Apr 20;67(2):258-66.


KT5823 inhibits cGMP-dependent protein kinase activity in vitro but not in intact human platelets and rat mesangial cells.

Burkhardt M, Glazova M, Gambaryan S, Vollkommer T, Butt E, Bader B, Heermeier K, Lincoln TM, Walter U, Palmetshofer A.

J Biol Chem. 2000 Oct 27;275(43):33536-41.


Nitric oxide dynamics and endothelial dysfunction in type II model of genetic diabetes.

Bitar MS, Wahid S, Mustafa S, Al-Saleh E, Dhaunsi GS, Al-Mulla F.

Eur J Pharmacol. 2005 Mar 21;511(1):53-64.


Early changes in vasoreactivity after simulated microgravity are due to an upregulation of the endothelium-dependent nitric oxide/cGMP pathway.

White AR, Ryoo S, Bugaj L, Attarzadeh DO, Thiyagarajan S, Chen K, Attwater S, Abbot B, Li D, Champion HC, Shoukas AA, Nyhan D, Hare JM, Berkowitz DE, Tuday EC.

Eur J Appl Physiol. 2010 Sep;110(2):395-404. doi: 10.1007/s00421-010-1514-7. Epub 2010 May 29.


Reduced vascular NO bioavailability in diabetes increases platelet activation in vivo.

Schäfer A, Alp NJ, Cai S, Lygate CA, Neubauer S, Eigenthaler M, Bauersachs J, Channon KM.

Arterioscler Thromb Vasc Biol. 2004 Sep;24(9):1720-6. Epub 2004 Jul 8.


Mechanisms underlying dysfunction of carotid arteries in genetically hyperlipidemic rabbits.

August M, Wingerter O, Oelze M, Wenzel P, Kleschyov AL, Daiber A, Mülsch A, Münzel T, Tsilimingas N.

Nitric Oxide. 2006 Nov;15(3):241-51. Epub 2006 Apr 4.


A potential mechanism for the impairment of nitric oxide formation caused by prolonged oral exposure to arsenate in rabbits.

Pi J, Horiguchi S, Sun Y, Nikaido M, Shimojo N, Hayashi T, Yamauchi H, Itoh K, Yamamoto M, Sun G, Waalkes MP, Kumagai Y.

Free Radic Biol Med. 2003 Jul 1;35(1):102-13.

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