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Results: 1 to 20 of 138

1.

Coupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassembly.

Zhao ZS, Manser E, Loo TH, Lim L.

Mol Cell Biol. 2000 Sep;20(17):6354-63.

PMID:
10938112
[PubMed - indexed for MEDLINE]
Free PMC Article
2.
3.

p85 beta-PIX is required for cell motility through phosphorylations of focal adhesion kinase and p38 MAP kinase.

Lee J, Jung ID, Chang WK, Park CG, Cho DY, Shin EY, Seo DW, Kim YK, Lee HW, Han JW, Lee HY.

Exp Cell Res. 2005 Jul 15;307(2):315-28.

PMID:
15893751
[PubMed - indexed for MEDLINE]
4.

Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling.

Turner CE, Brown MC, Perrotta JA, Riedy MC, Nikolopoulos SN, McDonald AR, Bagrodia S, Thomas S, Leventhal PS.

J Cell Biol. 1999 May 17;145(4):851-63.

PMID:
10330411
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness.

Brown MC, Cary LA, Jamieson JS, Cooper JA, Turner CE.

Mol Biol Cell. 2005 Sep;16(9):4316-28. Epub 2005 Jul 6.

PMID:
16000375
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

GIT1 activates p21-activated kinase through a mechanism independent of p21 binding.

Loo TH, Ng YW, Lim L, Manser E.

Mol Cell Biol. 2004 May;24(9):3849-59.

PMID:
15082779
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Constitutive p21-activated kinase (PAK) activation in breast cancer cells as a result of mislocalization of PAK to focal adhesions.

Stofega MR, Sanders LC, Gardiner EM, Bokoch GM.

Mol Biol Cell. 2004 Jun;15(6):2965-77. Epub 2004 Mar 26.

PMID:
15047871
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Paxillin phosphorylation at Ser273 localizes a GIT1-PIX-PAK complex and regulates adhesion and protrusion dynamics.

Nayal A, Webb DJ, Brown CM, Schaefer EM, Vicente-Manzanares M, Horwitz AR.

J Cell Biol. 2006 May 22;173(4):587-9.

PMID:
16717130
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Hic-5 interacts with GIT1 with a different binding mode from paxillin.

Nishiya N, Shirai T, Suzuki W, Nose K.

J Biochem. 2002 Aug;132(2):279-89.

PMID:
12153727
[PubMed - indexed for MEDLINE]
Free Article
10.

Sorting nexin 27 protein regulates trafficking of a p21-activated kinase (PAK) interacting exchange factor (β-Pix)-G protein-coupled receptor kinase interacting protein (GIT) complex via a PDZ domain interaction.

Valdes JL, Tang J, McDermott MI, Kuo JC, Zimmerman SP, Wincovitch SM, Waterman CM, Milgram SL, Playford MP.

J Biol Chem. 2011 Nov 11;286(45):39403-16. doi: 10.1074/jbc.M111.260802. Epub 2011 Sep 18.

PMID:
21926430
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors.

Manser E, Loo TH, Koh CG, Zhao ZS, Chen XQ, Tan L, Tan I, Leung T, Lim L.

Mol Cell. 1998 Jan;1(2):183-92.

PMID:
9659915
[PubMed - indexed for MEDLINE]
Free Article
12.

Regulation of the Cool/Pix proteins: key binding partners of the Cdc42/Rac targets, the p21-activated kinases.

Feng Q, Albeck JG, Cerione RA, Yang W.

J Biol Chem. 2002 Feb 15;277(7):5644-50. Epub 2001 Dec 10.

PMID:
11741931
[PubMed - indexed for MEDLINE]
Free Article
13.

GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin.

Schmalzigaug R, Garron ML, Roseman JT, Xing Y, Davidson CE, Arold ST, Premont RT.

Cell Signal. 2007 Aug;19(8):1733-44. Epub 2007 Mar 30.

PMID:
17467235
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Structural analysis of the SH3 domain of beta-PIX and its interaction with alpha-p21 activated kinase (PAK).

Mott HR, Nietlispach D, Evetts KA, Owen D.

Biochemistry. 2005 Aug 23;44(33):10977-83.

PMID:
16101281
[PubMed - indexed for MEDLINE]
15.

A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC.

Zhang H, Webb DJ, Asmussen H, Niu S, Horwitz AF.

J Neurosci. 2005 Mar 30;25(13):3379-88.

PMID:
15800193
[PubMed - indexed for MEDLINE]
Free Article
16.

Paxillin interactions.

Turner CE.

J Cell Sci. 2000 Dec;113 Pt 23:4139-40. Review.

PMID:
11069756
[PubMed - indexed for MEDLINE]
Free Article
17.

alphaPIX nucleotide exchange factor is activated by interaction with phosphatidylinositol 3-kinase.

Yoshii S, Tanaka M, Otsuki Y, Wang DY, Guo RJ, Zhu Y, Takeda R, Hanai H, Kaneko E, Sugimura H.

Oncogene. 1999 Oct 7;18(41):5680-90.

PMID:
10523848
[PubMed - indexed for MEDLINE]
Free Article
18.

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells.

Sells MA, Knaus UG, Bagrodia S, Ambrose DM, Bokoch GM, Chernoff J.

Curr Biol. 1997 Mar 1;7(3):202-10.

PMID:
9395435
[PubMed - indexed for MEDLINE]
Free Article
19.

betaPIX controls cell motility and neurite extension by regulating the distribution of GIT1.

Za L, Albertinazzi C, Paris S, Gagliani M, Tacchetti C, de Curtis I.

J Cell Sci. 2006 Jul 1;119(Pt 13):2654-66.

PMID:
16787945
[PubMed - indexed for MEDLINE]
Free Article
20.

Role of phospholipase Cgamma1 in cell spreading requires association with a beta-Pix/GIT1-containing complex, leading to activation of Cdc42 and Rac1.

Jones NP, Katan M.

Mol Cell Biol. 2007 Aug;27(16):5790-805. Epub 2007 Jun 11.

PMID:
17562871
[PubMed - indexed for MEDLINE]
Free PMC Article

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