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Results: 1 to 20 of 222

1.

MPTP activates c-Jun NH(2)-terminal kinase (JNK) and its upstream regulatory kinase MKK4 in nigrostriatal neurons in vivo.

Saporito MS, Thomas BA, Scott RW.

J Neurochem. 2000 Sep;75(3):1200-8.

PMID:
10936203
[PubMed - indexed for MEDLINE]
2.
3.

Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease.

Xia XG, Harding T, Weller M, Bieneman A, Uney JB, Schulz JB.

Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10433-8. Epub 2001 Aug 14.

PMID:
11504916
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Activation of the c-Jun N terminal kinase pathway in an animal model of Parkinson's disease.

Willesen MG, Gammeltoft S, Vaudano E.

Ann N Y Acad Sci. 2002 Nov;973:237-40.

PMID:
12485868
[PubMed - indexed for MEDLINE]
5.

JNK inhibitor protects dopaminergic neurons by reducing COX-2 expression in the MPTP mouse model of subacute Parkinson's disease.

Wang Y, Zhang Y, Wei Z, Li H, Zhou H, Zhang Z, Zhang Z.

J Neurol Sci. 2009 Oct 15;285(1-2):172-7. doi: 10.1016/j.jns.2009.06.034. Epub 2009 Jul 14.

PMID:
19604516
[PubMed - indexed for MEDLINE]
6.

CEP-1347/KT-7515, an inhibitor of SAPK/JNK pathway activation, promotes survival and blocks multiple events associated with Abeta-induced cortical neuron apoptosis.

Bozyczko-Coyne D, O'Kane TM, Wu ZL, Dobrzanski P, Murthy S, Vaught JL, Scott RW.

J Neurochem. 2001 May;77(3):849-63.

PMID:
11331414
[PubMed - indexed for MEDLINE]
7.

Inhibition of mixed lineage kinase 3 attenuates MPP+-induced neurotoxicity in SH-SY5Y cells.

Mathiasen JR, McKenna BA, Saporito MS, Ghadge GD, Roos RP, Holskin BP, Wu ZL, Trusko SP, Connors TC, Maroney AC, Thomas BA, Thomas JC, Bozyczko-Coyne D.

Brain Res. 2004 Apr 2;1003(1-2):86-97.

PMID:
15019567
[PubMed - indexed for MEDLINE]
8.

Selective activation of p38 mitogen-activated protein kinase in dopaminergic neurons of substantia nigra leads to nuclear translocation of p53 in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice.

Karunakaran S, Saeed U, Mishra M, Valli RK, Joshi SD, Meka DP, Seth P, Ravindranath V.

J Neurosci. 2008 Nov 19;28(47):12500-9. doi: 10.1523/JNEUROSCI.4511-08.2008.

PMID:
19020042
[PubMed - indexed for MEDLINE]
Free Article
9.

SP600125, a new JNK inhibitor, protects dopaminergic neurons in the MPTP model of Parkinson's disease.

Wang W, Shi L, Xie Y, Ma C, Li W, Su X, Huang S, Chen R, Zhu Z, Mao Z, Han Y, Li M.

Neurosci Res. 2004 Feb;48(2):195-202.

PMID:
14741394
[PubMed - indexed for MEDLINE]
10.
11.

Activation of apoptosis signal regulating kinase 1 (ASK1) and translocation of death-associated protein, Daxx, in substantia nigra pars compacta in a mouse model of Parkinson's disease: protection by alpha-lipoic acid.

Karunakaran S, Diwakar L, Saeed U, Agarwal V, Ramakrishnan S, Iyengar S, Ravindranath V.

FASEB J. 2007 Jul;21(9):2226-36. Epub 2007 Mar 16.

PMID:
17369508
[PubMed - indexed for MEDLINE]
Free Article
12.

Regulation of dopaminergic loss by Fas in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.

Hayley S, Crocker SJ, Smith PD, Shree T, Jackson-Lewis V, Przedborski S, Mount M, Slack R, Anisman H, Park DS.

J Neurosci. 2004 Feb 25;24(8):2045-53.

PMID:
14985447
[PubMed - indexed for MEDLINE]
Free Article
13.

The herbicide paraquat induces dopaminergic nigral apoptosis through sustained activation of the JNK pathway.

Peng J, Mao XO, Stevenson FF, Hsu M, Andersen JK.

J Biol Chem. 2004 Jul 30;279(31):32626-32. Epub 2004 May 20.

PMID:
15155744
[PubMed - indexed for MEDLINE]
Free Article
14.

Inhibition of the c-Jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons.

Harris CA, Deshmukh M, Tsui-Pierchala B, Maroney AC, Johnson EM Jr.

J Neurosci. 2002 Jan 1;22(1):103-13.

PMID:
11756493
[PubMed - indexed for MEDLINE]
Free Article
15.

Apoptosis of PC12 cells by 4-hydroxy-2-nonenal is mediated through selective activation of the c-Jun N-terminal protein kinase pathway.

Song BJ, Soh Y, Bae M, Pie J, Wan J, Jeong K.

Chem Biol Interact. 2001 Jan 30;130-132(1-3):943-54.

PMID:
11306108
[PubMed - indexed for MEDLINE]
16.

Regulation of axotomy-induced dopaminergic neuron death and c-Jun phosphorylation by targeted inhibition of cdc42 or mixed lineage kinase.

Crocker SJ, Hayley SP, Smith PD, Mount MP, Lamba WR, Callaghan SM, Slack RS, Park DS.

J Neurochem. 2006 Jan;96(2):489-99. Epub 2005 Nov 29.

PMID:
16336220
[PubMed - indexed for MEDLINE]
17.

Identification of JNK-dependent and -independent components of cerebellar granule neuron apoptosis.

Harris C, Maroney AC, Johnson EM Jr.

J Neurochem. 2002 Nov;83(4):992-1001.

PMID:
12421372
[PubMed - indexed for MEDLINE]
18.

c-Jun N-terminal kinase binding domain-dependent phosphorylation of mitogen-activated protein kinase kinase 4 and mitogen-activated protein kinase kinase 7 and balancing cross-talk between c-Jun N-terminal kinase and extracellular signal-regulated kinase pathways in cortical neurons.

Repici M, Mare L, Colombo A, Ploia C, Sclip A, Bonny C, Nicod P, Salmona M, Borsello T.

Neuroscience. 2009 Mar 3;159(1):94-103. doi: 10.1016/j.neuroscience.2008.11.049. Epub 2008 Dec 14.

PMID:
19135136
[PubMed - indexed for MEDLINE]
19.

JNK-independent activation of c-Jun during neuronal apoptosis induced by multiple DNA-damaging agents.

Besirli CG, Johnson EM Jr.

J Biol Chem. 2003 Jun 20;278(25):22357-66. Epub 2003 Apr 8.

PMID:
12684520
[PubMed - indexed for MEDLINE]
Free Article
20.

Selective activation of the c-Jun N-terminal protein kinase pathway during 4-hydroxynonenal-induced apoptosis of PC12 cells.

Soh Y, Jeong KS, Lee IJ, Bae MA, Kim YC, Song BJ.

Mol Pharmacol. 2000 Sep;58(3):535-41.

PMID:
10953046
[PubMed - indexed for MEDLINE]
Free Article

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