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Items: 1 to 20 of 157


The Rho family guanine nucleotide exchange factor Vav-2 regulates the development of cell-mediated cytotoxicity.

Billadeau DD, Mackie SM, Schoon RA, Leibson PJ.

J Exp Med. 2000 Aug 7;192(3):381-92.


Specific subdomains of Vav differentially affect T cell and NK cell activation.

Billadeau DD, Mackie SM, Schoon RA, Leibson PJ.

J Immunol. 2000 Apr 15;164(8):3971-81.


Vav family proteins couple to diverse cell surface receptors.

Moores SL, Selfors LM, Fredericks J, Breit T, Fujikawa K, Alt FW, Brugge JS, Swat W.

Mol Cell Biol. 2000 Sep;20(17):6364-73.


Vav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyte.

Tartare-Deckert S, Monthouel MN, Charvet C, Foucault I, Van Obberghen E, Bernard A, Altman A, Deckert M.

J Biol Chem. 2001 Jun 15;276(24):20849-57. Epub 2001 Mar 21.


The adaptor protein 3BP2 associates with VAV guanine nucleotide exchange factors to regulate NFAT activation by the B-cell antigen receptor.

Foucault I, Le Bras S, Charvet C, Moon C, Altman A, Deckert M.

Blood. 2005 Feb 1;105(3):1106-13. Epub 2004 Sep 2.


Vav-2 controls NFAT-dependent transcription in B- but not T-lymphocytes.

Doody GM, Billadeau DD, Clayton E, Hutchings A, Berland R, McAdam S, Leibson PJ, Turner M.

EMBO J. 2000 Nov 15;19(22):6173-84.


A functional T-cell receptor signaling pathway is required for p95vav activity.

Wu J, Katzav S, Weiss A.

Mol Cell Biol. 1995 Aug;15(8):4337-46.


Pleiotropic defects in TCR signaling in a Vav-1-null Jurkat T-cell line.

Cao Y, Janssen EM, Duncan AW, Altman A, Billadeau DD, Abraham RT.

EMBO J. 2002 Sep 16;21(18):4809-19.


Vav2 is an activator of Cdc42, Rac1, and RhoA.

Abe K, Rossman KL, Liu B, Ritola KD, Chiang D, Campbell SL, Burridge K, Der CJ.

J Biol Chem. 2000 Apr 7;275(14):10141-9.


Vav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducers in T cell antigen receptor-induced pathways.

Groysman M, Hornstein I, Alcover A, Katzav S.

J Biol Chem. 2002 Dec 20;277(51):50121-30. Epub 2002 Oct 16.


Vav-induced activation of the human IFN-gamma gene promoter is mediated by upregulation of AP-1 activity.

Kaminuma O, Elly C, Tanaka Y, Mori A, Liu YC, Altman A, Miyatake S.

FEBS Lett. 2002 Mar 13;514(2-3):153-8.


The Vav-Rac1 pathway in cytotoxic lymphocytes regulates the generation of cell-mediated killing.

Billadeau DD, Brumbaugh KM, Dick CJ, Schoon RA, Bustelo XR, Leibson PJ.

J Exp Med. 1998 Aug 3;188(3):549-59.


Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs.

Margolis B, Hu P, Katzav S, Li W, Oliver JM, Ullrich A, Weiss A, Schlessinger J.

Nature. 1992 Mar 5;356(6364):71-4.


Recognition and activation of Rho GTPases by Vav1 and Vav2 guanine nucleotide exchange factors.

Heo J, Thapar R, Campbell SL.

Biochemistry. 2005 May 3;44(17):6573-85.


Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras.

Khosravi-Far R, Chrzanowska-Wodnicka M, Solski PA, Eva A, Burridge K, Der CJ.

Mol Cell Biol. 1994 Oct;14(10):6848-57.


Role for the Rac1 exchange factor Vav in the signaling pathways leading to NK cell cytotoxicity.

Galandrini R, Palmieri G, Piccoli M, Frati L, Santoni A.

J Immunol. 1999 Mar 15;162(6):3148-52.


Tyrosine phosphorylation of adaptor protein 3BP2 induces T cell receptor-mediated activation of transcription factor.

Qu X, Kawauchi-Kamata K, Miah SM, Hatani T, Yamamura H, Sada K.

Biochemistry. 2005 Mar 15;44(10):3891-8.


hSiah2 is a new Vav binding protein which inhibits Vav-mediated signaling pathways.

Germani A, Romero F, Houlard M, Camonis J, Gisselbrecht S, Fischer S, Varin-Blank N.

Mol Cell Biol. 1999 May;19(5):3798-807.

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